| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the bendroflumethiazide-3934 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRA1B | adrenoceptor alpha 1B |
| AEBP1 | AE binding protein 1 |
| AFF1 | AF4/FMR2 family, member 1 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATP11A | ATPase, class VI, type 11A |
| BNC2 | basonuclin 2 |
| C3 | complement component 3 |
| C4BPB | complement component 4 binding protein, beta |
| C5AR1 | complement component 5a receptor 1 |
| CA9 | carbonic anhydrase IX |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC70 | coiled-coil domain containing 70 |
| CCL16 | chemokine (C-C motif) ligand 16 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COL1A1 | collagen, type I, alpha 1 |
| COMT | catechol-O-methyltransferase |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DFNB31 | deafness, autosomal recessive 31 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DRICH1 | aspartate-rich 1 |
| EFNB1 | ephrin-B1 |
| EMP1 | epithelial membrane protein 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERCC2 | excision repair cross-complementation group 2 |
| FAM182B | family with sequence similarity 182, member B |
| FCMR | Fc fragment of IgM receptor |
| FGF16 | fibroblast growth factor 16 |
| FGF5 | fibroblast growth factor 5 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FST | follistatin |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GFI1 | growth factor independent 1 transcription repressor |
| GHRHR | growth hormone releasing hormone receptor |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRM4 | glutamate receptor, metabotropic 4 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HGD | homogentisate 1,2-dioxygenase |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| HOXB5 | homeobox B5 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL22RA1 | interleukin 22 receptor, alpha 1 |
| IL36RN | interleukin 36 receptor antagonist |
| INHBE | inhibin, beta E |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| JMJD6 | jumonji domain containing 6 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| LAG3 | lymphocyte-activation gene 3 |
| LIMK1 | LIM domain kinase 1 |
| LOC440895 | two pore channel 3 pseudogene |
| LPAR3 | lysophosphatidic acid receptor 3 |
| MEGF6 | multiple EGF-like-domains 6 |
| MTSS1 | metastasis suppressor 1 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NEUROG1 | neurogenin 1 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NRP1 | neuropilin 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PIP | prolactin-induced protein |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLK3 | polo-like kinase 3 |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PSAT1 | phosphoserine aminotransferase 1 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SERHL2 | serine hydrolase-like 2 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SFTPB | surfactant protein B |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| STIM1 | stromal interaction molecule 1 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TBCD | tubulin folding cofactor D |
| TP63 | tumor protein p63 |
| TRIM38 | tripartite motif containing 38 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP10D | ATPase, class V, type 10D |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCO1 | beta-carotene oxygenase 1 |
| BMP4 | bone morphogenetic protein 4 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C5AR2 | complement component 5a receptor 2 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CARTPT | CART prepropeptide |
| CD34 | CD34 molecule |
| CD82 | CD82 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CEP295 | centrosomal protein 295kDa |
| CIDEB | cell death-inducing DFFA-like effector b |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CNTFR | ciliary neurotrophic factor receptor |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DYSF | dysferlin |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EXO5 | exonuclease 5 |
| FAM76A | family with sequence similarity 76, member A |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FFAR2 | free fatty acid receptor 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FOXI1 | forkhead box I1 |
| GATA4 | GATA binding protein 4 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BC | histone cluster 1, H2bc |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFNA17 | interferon, alpha 17 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL4R | interleukin 4 receptor |
| IRF6 | interferon regulatory factor 6 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| JAM3 | junctional adhesion molecule 3 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KLF8 | Kruppel-like factor 8 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MTA2 | metastasis associated 1 family, member 2 |
| MX2 | MX dynamin-like GTPase 2 |
| NLGN1 | neuroligin 1 |
| NOTCH4 | notch 4 |
| NPY4R | neuropeptide Y receptor Y4 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PCDHB13 | protocadherin beta 13 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB30 | RAB30, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBC1D19 | TBC1 domain family, member 19 |
| TEP1 | telomerase-associated protein 1 |
| TESC | tescalcin |
| TLR2 | toll-like receptor 2 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TOM1 | target of myb1 (chicken) |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| UBQLN4 | ubiquilin 4 |
| USB1 | U6 snRNA biogenesis 1 |
| USP19 | ubiquitin specific peptidase 19 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WDR76 | WD repeat domain 76 |
| XDH | xanthine dehydrogenase |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF573 | zinc finger protein 573 |
| ZNF682 | zinc finger protein 682 |
| ZNF747 | zinc finger protein 747 |