| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the bendroflumethiazide-4315 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY1 | adenylate cyclase 1 (brain) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARRB1 | arrestin, beta 1 |
| BCL2L1 | BCL2-like 1 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| CD1D | CD1d molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CELF2 | CUGBP, Elav-like family member 2 |
| CHAT | choline O-acetyltransferase |
| COL6A1 | collagen, type VI, alpha 1 |
| COPE | coatomer protein complex, subunit epsilon |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CYBB | cytochrome b-245, beta polypeptide |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DAPK1 | death-associated protein kinase 1 |
| DENND2D | DENN/MADD domain containing 2D |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DSCAM | Down syndrome cell adhesion molecule |
| DTNA | dystrobrevin, alpha |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ETV7 | ets variant 7 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FANCF | Fanconi anemia, complementation group F |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| HFE | hemochromatosis |
| HIST1H3E | histone cluster 1, H3e |
| HRK | harakiri, BCL2 interacting protein |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| HSF1 | heat shock transcription factor 1 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IDS | iduronate 2-sulfatase |
| IFFO1 | intermediate filament family orphan 1 |
| IGL | immunoglobulin lambda locus |
| IL5RA | interleukin 5 receptor, alpha |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAT2 | linker for activation of T cells family, member 2 |
| LY75 | lymphocyte antigen 75 |
| MAX | MYC associated factor X |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) |
| MED25 | mediator complex subunit 25 |
| MLXIP | MLX interacting protein |
| MPZ | myelin protein zero |
| MVB12B | multivesicular body subunit 12B |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOX1 | NADPH oxidase 1 |
| NPTXR | neuronal pentraxin receptor |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PIP | prolactin-induced protein |
| POU2AF1 | POU class 2 associating factor 1 |
| POU5F1B | POU class 5 homeobox 1B |
| PRAMEF10 | PRAME family member 10 |
| PRR5 | proline rich 5 (renal) |
| PTCH2 | patched 2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| QPRT | quinolinate phosphoribosyltransferase |
| RARB | retinoic acid receptor, beta |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RGS5 | regulator of G-protein signaling 5 |
| RPL18 | ribosomal protein L18 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SH2B1 | SH2B adaptor protein 1 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SPPL2B | signal peptide peptidase like 2B |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STAB1 | stabilin 1 |
| STC1 | stanniocalcin 1 |
| TBX2 | T-box 2 |
| TMEM206 | transmembrane protein 206 |
| TMSB15A | thymosin beta 15a |
| TNPO2 | transportin 2 |
| TONSL | tonsoku-like, DNA repair protein |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TTC22 | tetratricopeptide repeat domain 22 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| USH2A | Usher syndrome 2A (autosomal recessive, mild) |
| VPS9D1 | VPS9 domain containing 1 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| ZIM2 | zinc finger, imprinted 2 |
| Symbol | Name |
|---|---|
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| ARSB | arylsulfatase B |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CD101 | CD101 molecule |
| CD53 | CD53 molecule |
| CD70 | CD70 molecule |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLEC2B | C-type lectin domain family 2, member B |
| CRMP1 | collapsin response mediator protein 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| ELMO3 | engulfment and cell motility 3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FAM50B | family with sequence similarity 50, member B |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBRS | fibrosin |
| FGL1 | fibrinogen-like 1 |
| FZD10 | frizzled class receptor 10 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GSTM5 | glutathione S-transferase mu 5 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLX | H2.0-like homeobox |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HOXB2 | homeobox B2 |
| HOXC5 | homeobox C5 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFT54 | intraflagellar transport 54 |
| IL17RB | interleukin 17 receptor B |
| IL24 | interleukin 24 |
| IL4R | interleukin 4 receptor |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 |
| LRRC61 | leucine rich repeat containing 61 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| LYRM9 | LYR motif containing 9 |
| MATN3 | matrilin 3 |
| MDFI | MyoD family inhibitor |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NKX3-2 | NK3 homeobox 2 |
| NUBP1 | nucleotide binding protein 1 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PMCH | pro-melanin-concentrating hormone |
| POLL | polymerase (DNA directed), lambda |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RECQL4 | RecQ protein-like 4 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPAIN | RPA interacting protein |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SETD6 | SET domain containing 6 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC38A10 | solute carrier family 38, member 10 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| STAG3 | stromal antigen 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STRA6 | stimulated by retinoic acid 6 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAOK1 | TAO kinase 1 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TEP1 | telomerase-associated protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM19 | transmembrane protein 19 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VN1R1 | vomeronasal 1 receptor 1 |
| WDR76 | WD repeat domain 76 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF219 | zinc finger protein 219 |
| ZNF222 | zinc finger protein 222 |
| ZNF652 | zinc finger protein 652 |
| ZNF668 | zinc finger protein 668 |
| ZNF675 | zinc finger protein 675 |
