| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the benfotiamine-2177 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AHI1 | Abelson helper integration site 1 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BIN1 | bridging integrator 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BMP1 | bone morphogenetic protein 1 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDK10 | cyclin-dependent kinase 10 |
| CHPF | chondroitin polymerizing factor |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CRB1 | crumbs family member 1, photoreceptor morphogenesis associated |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CRYGD | crystallin, gamma D |
| CTIF | CBP80/20-dependent translation initiation factor |
| DOCK6 | dedicator of cytokinesis 6 |
| EFNA4 | ephrin-A4 |
| ELL | elongation factor RNA polymerase II |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EMP1 | epithelial membrane protein 1 |
| F11R | F11 receptor |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGL1 | fibrinogen-like 1 |
| FLT1 | fms-related tyrosine kinase 1 |
| FOXO1 | forkhead box O1 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GAS6 | growth arrest-specific 6 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GPR3 | G protein-coupled receptor 3 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HFE | hemochromatosis |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IGL | immunoglobulin lambda locus |
| IL6ST | interleukin 6 signal transducer |
| INO80B | INO80 complex subunit B |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL36 | kelch-like family member 36 |
| KRT18 | keratin 18, type I |
| LAMP1 | lysosomal-associated membrane protein 1 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MED31 | mediator complex subunit 31 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MYO9B | myosin IXB |
| MYOF | myoferlin |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OVOL2 | ovo-like zinc finger 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM3 | PDZ and LIM domain 3 |
| PHF1 | PHD finger protein 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLK3 | polo-like kinase 3 |
| PLSCR3 | phospholipid scramblase 3 |
| POU2F2 | POU class 2 homeobox 2 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRMT2IP | PRMT2 interacting protein |
| PSEN2 | presenilin 2 |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RFPL3S | RFPL3 antisense |
| RHEB | Ras homolog enriched in brain |
| RPL10 | ribosomal protein L10 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SFTPC | surfactant protein C |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| STX1A | syntaxin 1A (brain) |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| THBS1 | thrombospondin 1 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TK2 | thymidine kinase 2, mitochondrial |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TPM1 | tropomyosin 1 (alpha) |
| TUBA4B | tubulin, alpha 4b |
| WDR25 | WD repeat domain 25 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF609 | zinc finger protein 609 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ARMC7 | armadillo repeat containing 7 |
| ARRB1 | arrestin, beta 1 |
| ARSB | arylsulfatase B |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAK1 | BCL2-antagonist/killer 1 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| CBX7 | chromobox homolog 7 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD37 | CD37 molecule |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CES3 | carboxylesterase 3 |
| CHMP6 | charged multivesicular body protein 6 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CPTP | ceramide-1-phosphate transfer protein |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTRL | chymotrypsin-like |
| CXORF56 | chromosome X open reading frame 56 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EPHB6 | EPH receptor B6 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FOXN2 | forkhead box N2 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GALE | UDP-galactose-4-epimerase |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR19 | G protein-coupled receptor 19 |
| GPR22 | G protein-coupled receptor 22 |
| GTF2I | general transcription factor IIi |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BH | histone cluster 1, H2bh |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| METTL8 | methyltransferase like 8 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MKL2 | MKL/myocardin-like 2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTMR12 | myotubularin related protein 12 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PIPOX | pipecolic acid oxidase |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PLP1 | proteolipid protein 1 |
| PRAMEF11 | PRAME family member 11 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL10L | ribosomal protein L10-like |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| RRP1 | ribosomal RNA processing 1 |
| SALL2 | spalt-like transcription factor 2 |
| SCAI | suppressor of cancer cell invasion |
| SCAMP4 | secretory carrier membrane protein 4 |
| SETD1A | SET domain containing 1A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMAD5 | SMAD family member 5 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLR8 | toll-like receptor 8 |
| TMEM209 | transmembrane protein 209 |
| TMEM242 | transmembrane protein 242 |
| TPM3 | tropomyosin 3 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM25 | tripartite motif containing 25 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSPAN13 | tetraspanin 13 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| USP20 | ubiquitin specific peptidase 20 |
| VANGL1 | VANGL planar cell polarity protein 1 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF667 | zinc finger protein 667 |
| ZNF701 | zinc finger protein 701 |
| ZNF76 | zinc finger protein 76 |
