benfotiamine-3837 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the benfotiamine-3837 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACBD4 acyl-CoA binding domain containing 4
AKT2 v-akt murine thymoma viral oncogene homolog 2
ARNT aryl hydrocarbon receptor nuclear translocator
ASAP1-IT1 ASAP1 intronic transcript 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BTN3A1 butyrophilin, subfamily 3, member A1
C1ORF61 chromosome 1 open reading frame 61
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CAV3 caveolin 3
CCDC64 coiled-coil domain containing 64
CCDC87 coiled-coil domain containing 87
CCNK cyclin K
CD82 CD82 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CNTNAP2 contactin associated protein-like 2
COL9A3 collagen, type IX, alpha 3
CPQ carboxypeptidase Q
CUZD1 CUB and zona pellucida-like domains 1
CYLD cylindromatosis (turban tumor syndrome)
DAPK3 death-associated protein kinase 3
DCN decorin
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DICER1 dicer 1, ribonuclease type III
DPF1 D4, zinc and double PHD fingers family 1
DSTYK dual serine/threonine and tyrosine protein kinase
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
EXTL3 exostosin-like glycosyltransferase 3
FAM46C family with sequence similarity 46, member C
FHL1 four and a half LIM domains 1
FLOT1 flotillin 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GP6 glycoprotein VI (platelet)
GPR1 G protein-coupled receptor 1
GPR176 G protein-coupled receptor 176
GPR18 G protein-coupled receptor 18
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KHK ketohexokinase (fructokinase)
KMT2A lysine (K)-specific methyltransferase 2A
LOXL2 lysyl oxidase-like 2
LRP2 low density lipoprotein receptor-related protein 2
LRRC14 leucine rich repeat containing 14
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAGEB2 melanoma antigen family B2
MBNL3 muscleblind-like splicing regulator 3
MCM3AP minichromosome maintenance complex component 3 associated protein
MED16 mediator complex subunit 16
MET MET proto-oncogene, receptor tyrosine kinase
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MYO1C myosin IC
MYOF myoferlin
NCOR2 nuclear receptor corepressor 2
NEUROD1 neuronal differentiation 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NME5 NME/NM23 family member 5
OSBPL10 oxysterol binding protein-like 10
OTOR otoraplin
PGR progesterone receptor
PLK3 polo-like kinase 3
POFUT1 protein O-fucosyltransferase 1
PPARD peroxisome proliferator-activated receptor delta
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PSD4 pleckstrin and Sec7 domain containing 4
RERE arginine-glutamic acid dipeptide (RE) repeats
RFXAP regulatory factor X-associated protein
RRBP1 ribosome binding protein 1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RUNDC3A RUN domain containing 3A
RXRB retinoid X receptor, beta
SAYSD1 SAYSVFN motif domain containing 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SIRT5 sirtuin 5
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SOX4 SRY (sex determining region Y)-box 4
SP1 Sp1 transcription factor
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TECPR2 tectonin beta-propeller repeat containing 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP53I11 tumor protein p53 inducible protein 11
TRAK1 trafficking protein, kinesin binding 1
TTLL1 tubulin tyrosine ligase-like family member 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZER1 zyg-11 related, cell cycle regulator

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ADGRG2 adhesion G protein-coupled receptor G2
AFAP1 actin filament associated protein 1
ALS2CL ALS2 C-terminal like
AMH anti-Mullerian hormone
AMPD1 adenosine monophosphate deaminase 1
ANKH ANKH inorganic pyrophosphate transport regulator
ARR3 arrestin 3, retinal (X-arrestin)
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B9D2 B9 protein domain 2
BAX BCL2-associated X protein
C10ORF95 chromosome 10 open reading frame 95
C11ORF30 chromosome 11 open reading frame 30
C11ORF80 chromosome 11 open reading frame 80
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C22ORF46 chromosome 22 open reading frame 46
C4BPA complement component 4 binding protein, alpha
C8ORF44 chromosome 8 open reading frame 44
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CFD complement factor D (adipsin)
CHRM3 cholinergic receptor, muscarinic 3
CIC capicua transcriptional repressor
CRLF1 cytokine receptor-like factor 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DEF6 differentially expressed in FDCP 6 homolog (mouse)
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHB6 EPH receptor B6
FAM155A family with sequence similarity 155, member A
FAM76A family with sequence similarity 76, member A
FGF4 fibroblast growth factor 4
FLJ22184
FOSL1 FOS-like antigen 1
GALT galactose-1-phosphate uridylyltransferase
GCHFR GTP cyclohydrolase I feedback regulator
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR21 G protein-coupled receptor 21
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HDAC5 histone deacetylase 5
HIST1H1B histone cluster 1, H1b
HIST1H2AM histone cluster 1, H2am
HIST1H2BC histone cluster 1, H2bc
HIST1H2BM histone cluster 1, H2bm
HIST1H4C histone cluster 1, H4c
HOXA4 homeobox A4
IFNA14 interferon, alpha 14
IFT54 intraflagellar transport 54
INCENP inner centromere protein antigens 135/155kDa
INO80D INO80 complex subunit D
IPO8 importin 8
JMJD4 jumonji domain containing 4
KCTD7 potassium channel tetramerization domain containing 7
KIAA1107 KIAA1107
KLK5 kallikrein-related peptidase 5
KREMEN2 kringle containing transmembrane protein 2
KRT16 keratin 16, type I
LMNB1 lamin B1
METTL2B methyltransferase like 2B
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTA2 metastasis associated 1 family, member 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NPPA natriuretic peptide A
OLFML2A olfactomedin-like 2A
PITX2 paired-like homeodomain 2
PLEKHS1 pleckstrin homology domain containing, family S member 1
POLL polymerase (DNA directed), lambda
PTPRS protein tyrosine phosphatase, receptor type, S
QSER1 glutamine and serine rich 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL10L ribosomal protein L10-like
RPL23AP32 ribosomal protein L23a pseudogene 32
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
S100A9 S100 calcium binding protein A9
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPON2 spondin 2, extracellular matrix protein
SSBP3 single stranded DNA binding protein 3
STARD8 StAR-related lipid transfer (START) domain containing 8
TBC1D19 TBC1 domain family, member 19
TBL1Y transducin (beta)-like 1, Y-linked
TFF2 trefoil factor 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM19 transmembrane protein 19
TONSL tonsoku-like, DNA repair protein
TOR4A torsin family 4, member A
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
XYLT2 xylosyltransferase II
ZMAT4 zinc finger, matrin-type 4
ZNF134 zinc finger protein 134
ZNF358 zinc finger protein 358
ZNF639 zinc finger protein 639