| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the benfotiamine-3931 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AK1 | adenylate kinase 1 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARTN | artemin |
| C4BPA | complement component 4 binding protein, alpha |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CD22 | CD22 molecule |
| CD27 | CD27 molecule |
| CD28 | CD28 molecule |
| CDC25C | cell division cycle 25C |
| CDC42 | cell division cycle 42 |
| CDHR1 | cadherin-related family member 1 |
| CDK19 | cyclin-dependent kinase 19 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CEMP1 | cementum protein 1 |
| CLEC3B | C-type lectin domain family 3, member B |
| CLEC4A | C-type lectin domain family 4, member A |
| CLTA | clathrin, light chain A |
| COL1A1 | collagen, type I, alpha 1 |
| CRYGC | crystallin, gamma C |
| CTF1 | cardiotrophin 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DOK2 | docking protein 2, 56kDa |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM66D | family with sequence similarity 66, member D |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FLOT1 | flotillin 1 |
| FN1 | fibronectin 1 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR25 | G protein-coupled receptor 25 |
| GRIK4 | glutamate receptor, ionotropic, kainate 4 |
| HBB | hemoglobin, beta |
| HFE | hemochromatosis |
| HHAT | hedgehog acyltransferase |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HOXA11 | homeobox A11 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFNA10 | interferon, alpha 10 |
| INHA | inhibin, alpha |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KEL | Kell blood group, metallo-endopeptidase |
| KLK12 | kallikrein-related peptidase 12 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT32 | keratin 32, type I |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| MATN1 | matrilin 1, cartilage matrix protein |
| MFAP5 | microfibrillar associated protein 5 |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYOD1 | myogenic differentiation 1 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| OCLM | oculomedin |
| OLFML2B | olfactomedin-like 2B |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| OSBP2 | oxysterol binding protein 2 |
| P3H2 | prolyl 3-hydroxylase 2 |
| PAX2 | paired box 2 |
| PCBP3 | poly(rC) binding protein 3 |
| PCDHB11 | protocadherin beta 11 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PIP | prolactin-induced protein |
| POLL | polymerase (DNA directed), lambda |
| PTGDR2 | prostaglandin D2 receptor 2 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERHL2 | serine hydrolase-like 2 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC45A2 | solute carrier family 45, member 2 |
| SNCAIP | synuclein, alpha interacting protein |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SRRT | serrate, RNA effector molecule |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| STS | steroid sulfatase (microsomal), isozyme S |
| T | T, brachyury homolog (mouse) |
| TBCD | tubulin folding cofactor D |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TP53TG5 | TP53 target 5 |
| TRIP6 | thyroid hormone receptor interactor 6 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| UGT8 | UDP glycosyltransferase 8 |
| VCL | vinculin |
| VGLL3 | vestigial-like family member 3 |
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BMP10 | bone morphogenetic protein 10 |
| BMP15 | bone morphogenetic protein 15 |
| BTNL3 | butyrophilin-like 3 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1QB | complement component 1, q subcomponent, B chain |
| CBX4 | chromobox homolog 4 |
| CCNO | cyclin O |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD82 | CD82 molecule |
| CDHR2 | cadherin-related family member 2 |
| CDON | cell adhesion associated, oncogene regulated |
| CFHR4 | complement factor H-related 4 |
| CHM | choroideremia (Rab escort protein 1) |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CPTP | ceramide-1-phosphate transfer protein |
| CXXC4 | CXXC finger protein 4 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| DYSF | dysferlin |
| ELSPBP1 | epididymal sperm binding protein 1 |
| FAM131A | family with sequence similarity 131, member A |
| FAM188A | family with sequence similarity 188, member A |
| FBXO4 | F-box protein 4 |
| FHOD1 | formin homology 2 domain containing 1 |
| FLCN | folliculin |
| FLJ22184 | |
| GAST | gastrin |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| GSTM5 | glutathione S-transferase mu 5 |
| HDAC5 | histone deacetylase 5 |
| HIST1H4E | histone cluster 1, H4e |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IFNA17 | interferon, alpha 17 |
| IL15RA | interleukin 15 receptor, alpha |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LMNB1 | lamin B1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| MALL | mal, T-cell differentiation protein-like |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MX2 | MX dynamin-like GTPase 2 |
| NEUROD4 | neuronal differentiation 4 |
| NLGN1 | neuroligin 1 |
| NLRX1 | NLR family member X1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OCA2 | oculocutaneous albinism II |
| PAX9 | paired box 9 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PMEL | premelanosome protein |
| POLH | polymerase (DNA directed), eta |
| POPDC3 | popeye domain containing 3 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF208 | ring finger protein 208 |
| RPL10L | ribosomal protein L10-like |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRR1B | small proline-rich protein 1B |
| STMN3 | stathmin-like 3 |
| TCHH | trichohyalin |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TPCN1 | two pore segment channel 1 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| USB1 | U6 snRNA biogenesis 1 |
| USP36 | ubiquitin specific peptidase 36 |
| WDR33 | WD repeat domain 33 |
| ZNF286A | zinc finger protein 286A |
| ZNF442 | zinc finger protein 442 |
| ZNF682 | zinc finger protein 682 |
| ZNF696 | zinc finger protein 696 |
| ZNF770 | zinc finger protein 770 |
| ZNF862 | zinc finger protein 862 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
