| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the benfotiamine-4312 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACHE | acetylcholinesterase (Yt blood group) |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMACR | alpha-methylacyl-CoA racemase |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATN1 | atrophin 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C11ORF1 | chromosome 11 open reading frame 1 |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CALR | calreticulin |
| CARD10 | caspase recruitment domain family, member 10 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD22 | CD22 molecule |
| CD52 | CD52 molecule |
| CD82 | CD82 molecule |
| CDHR2 | cadherin-related family member 2 |
| CDK18 | cyclin-dependent kinase 18 |
| CFAP69 | cilia and flagella associated protein 69 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL8A2 | collagen, type VIII, alpha 2 |
| CRYAA | crystallin, alpha A |
| CYBB | cytochrome b-245, beta polypeptide |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| ESR1 | estrogen receptor 1 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 |
| FRMD4B | FERM domain containing 4B |
| GABRG3 | gamma-aminobutyric acid (GABA) A receptor, gamma 3 |
| GGT1 | gamma-glutamyltransferase 1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPR137 | G protein-coupled receptor 137 |
| GRM8 | glutamate receptor, metabotropic 8 |
| H1F0 | H1 histone family, member 0 |
| HDAC11 | histone deacetylase 11 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFFO1 | intermediate filament family orphan 1 |
| INO80D | INO80 complex subunit D |
| ITGB6 | integrin, beta 6 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIF25 | kinesin family member 25 |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 |
| KRT38 | keratin 38, type I |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LSAMP | limbic system-associated membrane protein |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MCOLN3 | mucolipin 3 |
| MINK1 | misshapen-like kinase 1 |
| MUC8 | mucin 8 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NPTX1 | neuronal pentraxin I |
| OLFM1 | olfactomedin 1 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PASK | PAS domain containing serine/threonine kinase |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLXND1 | plexin D1 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PXN | paxillin |
| RAB11B | RAB11B, member RAS oncogene family |
| RAG2 | recombination activating gene 2 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SFTPB | surfactant protein B |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPAG8 | sperm associated antigen 8 |
| SPATA1 | spermatogenesis associated 1 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYNDIG1 | synapse differentiation inducing 1 |
| TBCD | tubulin folding cofactor D |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TSKS | testis-specific serine kinase substrate |
| VGF | VGF nerve growth factor inducible |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ALPK1 | alpha-kinase 1 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CCNO | cyclin O |
| CEP295 | centrosomal protein 295kDa |
| CEP97 | centrosomal protein 97kDa |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CTSF | cathepsin F |
| DBF4B | DBF4 zinc finger B |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DENND5B | DENN/MADD domain containing 5B |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) |
| FA2H | fatty acid 2-hydroxylase |
| FER | fer (fps/fes related) tyrosine kinase |
| FKSG49 | FKSG49 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L | galactosidase, beta 1-like |
| GPATCH2L | G patch domain containing 2-like |
| GPX2 | glutathione peroxidase 2 |
| GRB2 | growth factor receptor-bound protein 2 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H4C | histone cluster 1, H4c |
| IFI6 | interferon, alpha-inducible protein 6 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KIAA0319L | KIAA0319-like |
| KIRREL | kin of IRRE like (Drosophila) |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MED18 | mediator complex subunit 18 |
| MGC12488 | |
| MIS18BP1 | MIS18 binding protein 1 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NDE1 | nudE neurodevelopment protein 1 |
| NDP | Norrie disease (pseudoglioma) |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NME5 | NME/NM23 family member 5 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NUTF2 | nuclear transport factor 2 |
| OSTF1 | osteoclast stimulating factor 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRR14L | proline rich 14-like |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RBBP5 | retinoblastoma binding protein 5 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RSRC1 | arginine/serine-rich coiled-coil 1 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SMAD5 | SMAD family member 5 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPIN1 | spindlin 1 |
| SPRYD7 | SPRY domain containing 7 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STAG3 | stromal antigen 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYTL2 | synaptotagmin-like 2 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TAOK1 | TAO kinase 1 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM209 | transmembrane protein 209 |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZNF160 | zinc finger protein 160 |
| ZNF264 | zinc finger protein 264 |
| ZNF286A | zinc finger protein 286A |
| ZNF426 | zinc finger protein 426 |
| ZNF652 | zinc finger protein 652 |
| ZNF667 | zinc finger protein 667 |
| ZNF668 | zinc finger protein 668 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF721 | zinc finger protein 721 |
| ZNF91 | zinc finger protein 91 |
