benfotiamine Gene Set
Genes
16 genes differentially expressed following the benfotiamine small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
4.81278
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
4.13998
|
|
DNAJC4
|
DnaJ (Hsp40) homolog, subfamily C, member 4
|
3.6121
|
|
ZNF667
|
zinc finger protein 667
|
3.3793
|
|
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
|
3.32087
|
|
FRS2
|
fibroblast growth factor receptor substrate 2
|
3.27731
|
|
GLI2
|
GLI family zinc finger 2
|
3.24314
|
|
ZBED2
|
zinc finger, BED-type containing 2
|
3.23049
|
|
ZNF587
|
zinc finger protein 587
|
3.20308
|
|
SENP7
|
SUMO1/sentrin specific peptidase 7
|
3.16347
|
|
KLHDC2
|
kelch domain containing 2
|
3.1602
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GDF5
|
growth differentiation factor 5
|
-3.37203
|
|
CASK
|
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
|
-3.33803
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-3.29891
|
|
RAB27A
|
RAB27A, member RAS oncogene family
|
-3.25602
|
|
C5
|
complement component 5
|
-3.03351
|
