benperidol-2836 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the benperidol-2836 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ADCY7 adenylate cyclase 7
AEBP1 AE binding protein 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ATM ATM serine/threonine kinase
BIRC7 baculoviral IAP repeat containing 7
BLZF1 basic leucine zipper nuclear factor 1
C2ORF27A chromosome 2 open reading frame 27A
CA12 carbonic anhydrase XII
CCDC132 coiled-coil domain containing 132
CCDC9 coiled-coil domain containing 9
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD200 CD200 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CRTC1 CREB regulated transcription coactivator 1
DEFA5 defensin, alpha 5, Paneth cell-specific
DOK4 docking protein 4
DZIP1 DAZ interacting zinc finger protein 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELK1 ELK1, member of ETS oncogene family
ELOVL5 ELOVL fatty acid elongase 5
EML2 echinoderm microtubule associated protein like 2
EPX eosinophil peroxidase
F13A1 coagulation factor XIII, A1 polypeptide
FAM49B family with sequence similarity 49, member B
FFAR2 free fatty acid receptor 2
FOXN3 forkhead box N3
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GPR22 G protein-coupled receptor 22
GSK3A glycogen synthase kinase 3 alpha
HFE hemochromatosis
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPX hemopexin
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IDS iduronate 2-sulfatase
IPW imprinted in Prader-Willi syndrome (non-protein coding)
IRAK3 interleukin-1 receptor-associated kinase 3
KMT2A lysine (K)-specific methyltransferase 2A
KRT6B keratin 6B, type II
LHB luteinizing hormone beta polypeptide
LIF leukemia inhibitory factor
LPIN1 lipin 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LSP1 lymphocyte-specific protein 1
MAOB monoamine oxidase B
MBTD1 mbt domain containing 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MINK1 misshapen-like kinase 1
MITF microphthalmia-associated transcription factor
MKL1 megakaryoblastic leukemia (translocation) 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MOB1A MOB kinase activator 1A
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
NAIP NLR family, apoptosis inhibitory protein
NCALD neurocalcin delta
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOX4 NADPH oxidase 4
NPC1 Niemann-Pick disease, type C1
NPHP1 nephronophthisis 1 (juvenile)
NRF1 nuclear respiratory factor 1
NRL neural retina leucine zipper
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NXPH4 neurexophilin 4
OGFR opioid growth factor receptor
PCBP3 poly(rC) binding protein 3
PGR progesterone receptor
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
POU4F2 POU class 4 homeobox 2
PRR14L proline rich 14-like
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASA3 RAS p21 protein activator 3
RNFT1 ring finger protein, transmembrane 1
RRAGD Ras-related GTP binding D
RSG1 REM2 and RAB-like small GTPase 1
RSU1 Ras suppressor protein 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKAP1 src kinase associated phosphoprotein 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SRCAP Snf2-related CREBBP activator protein
TM4SF1 transmembrane 4 L six family member 1
TOR4A torsin family 4, member A
TRAK1 trafficking protein, kinesin binding 1
TSPAN9 tetraspanin 9
USP34 ubiquitin specific peptidase 34
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VEGFA vascular endothelial growth factor A
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WIPF1 WAS/WASL interacting protein family, member 1
ZNF652 zinc finger protein 652
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARL15 ADP-ribosylation factor-like 15
ARMC6 armadillo repeat containing 6
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP11B ATPase, class VI, type 11B
BAK1 BCL2-antagonist/killer 1
BEX4 brain expressed, X-linked 4
C14ORF132 chromosome 14 open reading frame 132
C1ORF159 chromosome 1 open reading frame 159
C5 complement component 5
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CCS copper chaperone for superoxide dismutase
CLDN15 claudin 15
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CPTP ceramide-1-phosphate transfer protein
CTC1 CTS telomere maintenance complex component 1
DGAT1 diacylglycerol O-acyltransferase 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DSCAM Down syndrome cell adhesion molecule
DVL1 dishevelled segment polarity protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2R coagulation factor II (thrombin) receptor
FAM114A2 family with sequence similarity 114, member A2
FBXL2 F-box and leucine-rich repeat protein 2
FPGS folylpolyglutamate synthase
FSCN1 fascin actin-bundling protein 1
GPALPP1 GPALPP motifs containing 1
IL4R interleukin 4 receptor
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
JMJD4 jumonji domain containing 4
JUNB jun B proto-oncogene
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0894 KIAA0894 protein
KIF16B kinesin family member 16B
KIF18A kinesin family member 18A
KLF3 Kruppel-like factor 3 (basic)
KRT13 keratin 13, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHX6 LIM homeobox 6
LIN37 lin-37 DREAM MuvB core complex component
LOC390998 ribosomal protein L10 pseudogene
LY6G5C lymphocyte antigen 6 complex, locus G5C
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MED15 mediator complex subunit 15
METTL2B methyltransferase like 2B
MICALL2 MICAL-like 2
MTERF1 mitochondrial transcription termination factor 1
MYH9 myosin, heavy chain 9, non-muscle
NABP2 nucleic acid binding protein 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NFE2L3 nuclear factor, erythroid 2-like 3
NFS1 NFS1 cysteine desulfurase
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PARP12 poly (ADP-ribose) polymerase family, member 12
PDGFRL platelet-derived growth factor receptor-like
PECR peroxisomal trans-2-enoyl-CoA reductase
PHEX phosphate regulating endopeptidase homolog, X-linked
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLA2G15 phospholipase A2, group XV
PODXL2 podocalyxin-like 2
POLH polymerase (DNA directed), eta
PRPH peripherin
PRR7 proline rich 7 (synaptic)
SETD1A SET domain containing 1A
SIX1 SIX homeobox 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC38A10 solute carrier family 38, member 10
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SYCP2 synaptonemal complex protein 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
THRAP3 thyroid hormone receptor associated protein 3
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMEM180 transmembrane protein 180
TMSB15A thymosin beta 15a
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAIP TRAF interacting protein
TTC23 tetratricopeptide repeat domain 23
TUBA3D tubulin, alpha 3d
TUBG2 tubulin, gamma 2
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WLS wntless Wnt ligand secretion mediator
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YIPF3 Yip1 domain family, member 3
ZDHHC14 zinc finger, DHHC-type containing 14
ZFP69B ZFP69 zinc finger protein B
ZNF219 zinc finger protein 219
ZNF329 zinc finger protein 329
ZNF34 zinc finger protein 34
ZNF623 zinc finger protein 623