benperidol-4196 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the benperidol-4196 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSS3 acyl-CoA synthetase short-chain family member 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKAP5 A kinase (PRKA) anchor protein 5
ANGPTL4 angiopoietin-like 4
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASGR2 asialoglycoprotein receptor 2
ATG10 autophagy related 10
ATP10A ATPase, class V, type 10A
C11ORF21 chromosome 11 open reading frame 21
CCDC64 coiled-coil domain containing 64
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFB complement factor B
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLCN7 chloride channel, voltage-sensitive 7
CLUL1 clusterin-like 1 (retinal)
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL21A1 collagen, type XXI, alpha 1
CT62 cancer/testis antigen 62
CTC1 CTS telomere maintenance complex component 1
CTNS cystinosin, lysosomal cystine transporter
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DGCR2 DiGeorge syndrome critical region gene 2
DMBT1 deleted in malignant brain tumors 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOCK6 dedicator of cytokinesis 6
DPYS dihydropyrimidinase
EGOT eosinophil granule ontogeny transcript (non-protein coding)
FAM63A family with sequence similarity 63, member A
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GHRHR growth hormone releasing hormone receptor
GJA8 gap junction protein, alpha 8, 50kDa
GLUL glutamate-ammonia ligase
GLYAT glycine-N-acyltransferase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GP2 glycoprotein 2 (zymogen granule membrane)
GPM6A glycoprotein M6A
GPR21 G protein-coupled receptor 21
HBB hemoglobin, beta
HDAC6 histone deacetylase 6
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HHAT hedgehog acyltransferase
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IL11 interleukin 11
ING4 inhibitor of growth family, member 4
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNIP1 Kv channel interacting protein 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LINC00115 long intergenic non-protein coding RNA 115
LOC100286895 cell division cycle 27 homolog pseudogene
LRP1 low density lipoprotein receptor-related protein 1
LRRC15 leucine rich repeat containing 15
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MPZ myelin protein zero
MTAP methylthioadenosine phosphorylase
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRF1 nuclear respiratory factor 1
NTNG1 netrin G1
OGDHL oxoglutarate dehydrogenase-like
PGPEP1 pyroglutamyl-peptidase I
PIAS4 protein inhibitor of activated STAT, 4
PKNOX2 PBX/knotted 1 homeobox 2
PLK4 polo-like kinase 4
PRB1 proline-rich protein BstNI subfamily 1
PRKCE protein kinase C, epsilon
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RIN3 Ras and Rab interactor 3
ROM1 retinal outer segment membrane protein 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RUFY3 RUN and FYVE domain containing 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDS serine dehydratase
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SETDB1 SET domain, bifurcated 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SMAD5-AS1 SMAD5 antisense RNA 1
SMOX spermine oxidase
SSTR5 somatostatin receptor 5
THBS3 thrombospondin 3
THSD4 thrombospondin, type I, domain containing 4
TK2 thymidine kinase 2, mitochondrial
TM4SF4 transmembrane 4 L six family member 4
TMEM180 transmembrane protein 180
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRAC T cell receptor alpha constant
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
WSB1 WD repeat and SOCS box containing 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZHX3 zinc fingers and homeoboxes 3
ZNF467 zinc finger protein 467

decreased expression

Symbol Name
ACE angiotensin I converting enzyme
ADAM23 ADAM metallopeptidase domain 23
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANXA10 annexin A10
ARHGAP22 Rho GTPase activating protein 22
ARPIN actin-related protein 2/3 complex inhibitor
ARRB2 arrestin, beta 2
BCAS3 breast carcinoma amplified sequence 3
BFSP1 beaded filament structural protein 1, filensin
C1R complement component 1, r subcomponent
CAMKMT calmodulin-lysine N-methyltransferase
CAPN15 calpain 15
CCNT1 cyclin T1
CD68 CD68 molecule
CLTCL1 clathrin, heavy chain-like 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRYGC crystallin, gamma C
CYBRD1 cytochrome b reductase 1
DSPP dentin sialophosphoprotein
EBF2 early B-cell factor 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM173A family with sequence similarity 173, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLT4 fms-related tyrosine kinase 4
FMO4 flavin containing monooxygenase 4
FOXA1 forkhead box A1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GIF gastric intrinsic factor (vitamin B synthesis)
GPX2 glutathione peroxidase 2
GSTA3 glutathione S-transferase alpha 3
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BN histone cluster 1, H2bn
HOXC10 homeobox C10
IFT140 intraflagellar transport 140
IRF2 interferon regulatory factor 2
ITGB7 integrin, beta 7
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KIAA0319L KIAA0319-like
KLF13 Kruppel-like factor 13
LIME1 Lck interacting transmembrane adaptor 1
LOC157562 uncharacterized LOC157562
LPAR4 lysophosphatidic acid receptor 4
LRRC23 leucine rich repeat containing 23
LRRC61 leucine rich repeat containing 61
LTC4S leukotriene C4 synthase
LY6D lymphocyte antigen 6 complex, locus D
MAGEF1 melanoma antigen family F1
MANBA mannosidase, beta A, lysosomal
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MB myoglobin
MGP matrix Gla protein
MRPS18C mitochondrial ribosomal protein S18C
MTSS1L metastasis suppressor 1-like
MYO1F myosin IF
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBEAL2 neurobeachin-like 2
NSUN6 NOP2/Sun domain family, member 6
NTSR1 neurotensin receptor 1 (high affinity)
ODF2 outer dense fiber of sperm tails 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAIP2B poly(A) binding protein interacting protein 2B
PLBD1 phospholipase B domain containing 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PROX1 prospero homeobox 1
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCIN scinderin
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERGEF secretion regulating guanine nucleotide exchange factor
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
TBC1D17 TBC1 domain family, member 17
TGFBI transforming growth factor, beta-induced, 68kDa
TIMP4 TIMP metallopeptidase inhibitor 4
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLN1 talin 1
TMPRSS4 transmembrane protease, serine 4
TNK1 tyrosine kinase, non-receptor, 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
VASH1 vasohibin 1
ZNF480 zinc finger protein 480
ZNF747 zinc finger protein 747