benperidol-4781 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the benperidol-4781 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
AKR1C4 aldo-keto reductase family 1, member C4
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANP32A-IT1 ANP32A intronic transcript 1
AREG amphiregulin
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BDKRB2 bradykinin receptor B2
BGLAP bone gamma-carboxyglutamate (gla) protein
BGN biglycan
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CALD1 caldesmon 1
CCDC106 coiled-coil domain containing 106
CCDC57 coiled-coil domain containing 57
CD1E CD1e molecule
CDK17 cyclin-dependent kinase 17
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CNIH3 cornichon family AMPA receptor auxiliary protein 3
COL1A2 collagen, type I, alpha 2
CTIF CBP80/20-dependent translation initiation factor
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYTH1 cytohesin 1
DHODH dihydroorotate dehydrogenase (quinone)
DICER1 dicer 1, ribonuclease type III
DMWD dystrophia myotonica, WD repeat containing
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK9 dedicator of cytokinesis 9
DRD2 dopamine receptor D2
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMID1 EMI domain containing 1
EPN1 epsin 1
ERCC2 excision repair cross-complementation group 2
FGFR1 fibroblast growth factor receptor 1
FYN FYN proto-oncogene, Src family tyrosine kinase
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GUSBP3 glucuronidase, beta pseudogene 3
HFE hemochromatosis
HHLA1 HERV-H LTR-associating 1
HIST1H1T histone cluster 1, H1t
HOXA4 homeobox A4
HPCA hippocalcin
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
HYI hydroxypyruvate isomerase (putative)
IFNA16 interferon, alpha 16
IFNA6 interferon, alpha 6
IL1R2 interleukin 1 receptor, type II
IL1RN interleukin 1 receptor antagonist
INHBA inhibin, beta A
INHBE inhibin, beta E
IRF4 interferon regulatory factor 4
KANK1 KN motif and ankyrin repeat domains 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDM8 lysine (K)-specific demethylase 8
KSR1 kinase suppressor of ras 1
MAPK7 mitogen-activated protein kinase 7
MBL2 mannose-binding lectin (protein C) 2, soluble
MECOM MDS1 and EVI1 complex locus
MEGF6 multiple EGF-like-domains 6
MUC5B mucin 5B, oligomeric mucus/gel-forming
NCR2 natural cytotoxicity triggering receptor 2
NF1 neurofibromin 1
NLRP3 NLR family, pyrin domain containing 3
NPFF neuropeptide FF-amide peptide precursor
OLFML2A olfactomedin-like 2A
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PEG10 paternally expressed 10
POU1F1 POU class 1 homeobox 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRDX2 peroxiredoxin 2
RAB27B RAB27B, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SPN sialophorin
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRP72 signal recognition particle 72kDa
STOML1 stomatin (EPB72)-like 1
SYMPK symplekin
TIMELESS timeless circadian clock
TLDC1 TBC/LysM-associated domain containing 1
TMEM212 transmembrane protein 212
TNK2 tyrosine kinase, non-receptor, 2
TPSB2 tryptase beta 2 (gene/pseudogene)
TREX1 three prime repair exonuclease 1
TRIB2 tribbles pseudokinase 2
ZFPL1 zinc finger protein-like 1
ZNF589 zinc finger protein 589
ZNF76 zinc finger protein 76
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AKTIP AKT interacting protein
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARHGAP12 Rho GTPase activating protein 12
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASB7 ankyrin repeat and SOCS box containing 7
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AUH AU RNA binding protein/enoyl-CoA hydratase
C2ORF44 chromosome 2 open reading frame 44
C9ORF40 chromosome 9 open reading frame 40
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC109B coiled-coil domain containing 109B
CDKN3 cyclin-dependent kinase inhibitor 3
CEP97 centrosomal protein 97kDa
COMMD10 COMM domain containing 10
CTNNBIP1 catenin, beta interacting protein 1
CYB5R4 cytochrome b5 reductase 4
DNA2 DNA replication helicase/nuclease 2
DNAAF2 dynein, axonemal, assembly factor 2
DPY19L4 dpy-19-like 4 (C. elegans)
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERBB2IP erbb2 interacting protein
ERCC6L excision repair cross-complementation group 6-like
EXO1 exonuclease 1
FAIM Fas apoptotic inhibitory molecule
FAM13B family with sequence similarity 13, member B
FAM3C family with sequence similarity 3, member C
FAM60A family with sequence similarity 60, member A
FASTKD5 FAST kinase domains 5
FBXL2 F-box and leucine-rich repeat protein 2
FBXO5 F-box protein 5
FZD3 frizzled class receptor 3
GBAS glioblastoma amplified sequence
GDE1 glycerophosphodiester phosphodiesterase 1
GPHN gephyrin
HP1BP3 heterochromatin protein 1, binding protein 3
IMPAD1 inositol monophosphatase domain containing 1
INPP5K inositol polyphosphate-5-phosphatase K
ISOC1 isochorismatase domain containing 1
ITFG1 integrin alpha FG-GAP repeat containing 1
KIF23 kinesin family member 23
LRRC16A leucine rich repeat containing 16A
LZTR1 leucine-zipper-like transcription regulator 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MANEA mannosidase, endo-alpha
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAT2B methionine adenosyltransferase II, beta
MDM1 Mdm1 nuclear protein homolog (mouse)
MED17 mediator complex subunit 17
MGC12488
MPC1 mitochondrial pyruvate carrier 1
MTERF1 mitochondrial transcription termination factor 1
NAE1 NEDD8 activating enzyme E1 subunit 1
NCAM2 neural cell adhesion molecule 2
NFE2L2 nuclear factor, erythroid 2-like 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NUP155 nucleoporin 155kDa
OAT ornithine aminotransferase
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PCNXL4 pecanex-like 4 (Drosophila)
PDCD10 programmed cell death 10
POLI polymerase (DNA directed) iota
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
RGS17 regulator of G-protein signaling 17
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPL23AP32 ribosomal protein L23a pseudogene 32
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SEC24B SEC24 family member B
SELT selenoprotein T
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SIAH2 siah E3 ubiquitin protein ligase 2
SLBP stem-loop binding protein
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNIP1 Smad nuclear interacting protein 1
SNX16 sorting nexin 16
SOAT1 sterol O-acyltransferase 1
SPDL1 spindle apparatus coiled-coil protein 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
THAP1 THAP domain containing, apoptosis associated protein 1
TMEM135 transmembrane protein 135
TMEM230 transmembrane protein 230
TMEM243 transmembrane protein 243, mitochondrial
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNRC6B trinucleotide repeat containing 6B
TRAPPC13 trafficking protein particle complex 13
TRIM5 tripartite motif containing 5
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TTC4 tetratricopeptide repeat domain 4
USP6NL USP6 N-terminal like
UVRAG UV radiation resistance associated
VCPKMT valosin containing protein lysine (K) methyltransferase
WDR5B WD repeat domain 5B
WRB tryptophan rich basic protein
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF623 zinc finger protein 623