benserazide-641 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the benserazide-641 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX3 acyl-CoA oxidase 3, pristanoyl
ADGRL1 adhesion G protein-coupled receptor L1
ADM2 adrenomedullin 2
AGGF1 angiogenic factor with G patch and FHA domains 1
AQP3 aquaporin 3 (Gill blood group)
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGAP19 Rho GTPase activating protein 19
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASB7 ankyrin repeat and SOCS box containing 7
BAIAP2 BAI1-associated protein 2
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCAR3 breast cancer anti-estrogen resistance 3
BCL7A B-cell CLL/lymphoma 7A
BICD1 bicaudal D homolog 1 (Drosophila)
C19ORF66 chromosome 19 open reading frame 66
CCDC176 coiled-coil domain containing 176
CCNL2 cyclin L2
CDKN2A cyclin-dependent kinase inhibitor 2A
CDYL chromodomain protein, Y-like
CEP131 centrosomal protein 131kDa
CNTFR ciliary neurotrophic factor receptor
CPE carboxypeptidase E
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCLRE1A DNA cross-link repair 1A
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
EFCAB1 EF-hand calcium binding domain 1
EFNB3 ephrin-B3
ERCC2 excision repair cross-complementation group 2
FAM114A2 family with sequence similarity 114, member A2
FAM153A family with sequence similarity 153, member A
FBXO31 F-box protein 31
FKBP8 FK506 binding protein 8, 38kDa
FOXO1 forkhead box O1
GPER1 G protein-coupled estrogen receptor 1
GRK6 G protein-coupled receptor kinase 6
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HEXIM1 hexamethylene bis-acetamide inducible 1
HMBOX1 homeobox containing 1
HMGB3P1 high mobility group box 3 pseudogene 1
HMGXB3 HMG box domain containing 3
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHM immunoglobulin heavy constant mu
IL4R interleukin 4 receptor
INTS7 integrator complex subunit 7
IRF5 interferon regulatory factor 5
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK15 potassium channel, two pore domain subfamily K, member 15
KLF15 Kruppel-like factor 15
LENEP lens epithelial protein
LIAS lipoic acid synthetase
LINC00339 long intergenic non-protein coding RNA 339
LMF2 lipase maturation factor 2
MARK2 MAP/microtubule affinity-regulating kinase 2
MBD3 methyl-CpG binding domain protein 3
MED18 mediator complex subunit 18
MED7 mediator complex subunit 7
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MOGAT2 monoacylglycerol O-acyltransferase 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOAZFP nucleolar atypical zinc finger
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PECR peroxisomal trans-2-enoyl-CoA reductase
PHC1 polyhomeotic homolog 1 (Drosophila)
PHEX phosphate regulating endopeptidase homolog, X-linked
PLSCR1 phospholipid scramblase 1
PQLC3 PQ loop repeat containing 3
PROP1 PROP paired-like homeobox 1
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REC8 REC8 meiotic recombination protein
RPE ribulose-5-phosphate-3-epimerase
SAMHD1 SAM domain and HD domain 1
SAP18 Sin3A-associated protein, 18kDa
SEC23B Sec23 homolog B (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERBP1 SERPINE1 mRNA binding protein 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SNX13 sorting nexin 13
SPTBN5 spectrin, beta, non-erythrocytic 5
TBL1X transducin (beta)-like 1X-linked
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM187 transmembrane protein 187
TNPO1 transportin 1
TTC26 tetratricopeptide repeat domain 26
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
VRK3 vaccinia related kinase 3
XYLT2 xylosyltransferase II
ZBTB35 zinc finger and BTB domain containing 35
ZFP64 ZFP64 zinc finger protein
ZFR zinc finger RNA binding protein
ZNF787 zinc finger protein 787

decreased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADGRG3 adhesion G protein-coupled receptor G3
AHSP alpha hemoglobin stabilizing protein
ALPK1 alpha-kinase 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
ART1 ADP-ribosyltransferase 1
ATXN8OS ATXN8 opposite strand (non-protein coding)
BCL10 B-cell CLL/lymphoma 10
C17ORF53 chromosome 17 open reading frame 53
C17ORF80 chromosome 17 open reading frame 80
CA7 carbonic anhydrase VII
CAMKMT calmodulin-lysine N-methyltransferase
CARTPT CART prepropeptide
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCDC64 coiled-coil domain containing 64
CCL19 chemokine (C-C motif) ligand 19
CD177 CD177 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD79A CD79a molecule, immunoglobulin-associated alpha
CD80 CD80 molecule
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CNTD2 cyclin N-terminal domain containing 2
CPNE7 copine VII
CST4 cystatin S
CXCL9 chemokine (C-X-C motif) ligand 9
DISC1 disrupted in schizophrenia 1
ECE2 endothelin converting enzyme 2
EGFL7 EGF-like-domain, multiple 7
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERN2 endoplasmic reticulum to nucleus signaling 2
ESPN espin
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FRMD1 FERM domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMIP GEM interacting protein
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPR182 G protein-coupled receptor 182
HIST1H4D histone cluster 1, H4d
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IGFALS insulin-like growth factor binding protein, acid labile subunit
INO80D INO80 complex subunit D
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KLK1 kallikrein 1
KRT32 keratin 32, type I
KRT85 keratin 85, type II
LY86 lymphocyte antigen 86
MX2 MX dynamin-like GTPase 2
MYL1 myosin, light chain 1, alkali; skeletal, fast
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
PADI1 peptidyl arginine deiminase, type I
PARM1 prostate androgen-regulated mucin-like protein 1
PCDHB6 protocadherin beta 6
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PLXNB3 plexin B3
PMEPA1 prostate transmembrane protein, androgen induced 1
PON3 paraoxonase 3
PRAF2 PRA1 domain family, member 2
PRDM5 PR domain containing 5
PRL prolactin
PTH1R parathyroid hormone 1 receptor
PTPRN protein tyrosine phosphatase, receptor type, N
PTPRS protein tyrosine phosphatase, receptor type, S
PYHIN1 pyrin and HIN domain family, member 1
RAB33B RAB33B, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RGS17 regulator of G-protein signaling 17
RIC3 RIC3 acetylcholine receptor chaperone
S1PR4 sphingosine-1-phosphate receptor 4
SCML1 sex comb on midleg-like 1 (Drosophila)
SEC14L5 SEC14-like 5 (S. cerevisiae)
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SPON2 spondin 2, extracellular matrix protein
SRPK3 SRSF protein kinase 3
SUSD4 sushi domain containing 4
THBS3 thrombospondin 3
TRAPPC12 trafficking protein particle complex 12
TSPAN32 tetraspanin 32
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZBTB16 zinc finger and BTB domain containing 16
ZNF180 zinc finger protein 180
ZNF276 zinc finger protein 276
ZNF557 zinc finger protein 557
ZNF85 zinc finger protein 85