benzamil-3635 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the benzamil-3635 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APOC1 apolipoprotein C-I
ATF3 activating transcription factor 3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BDKRB2 bradykinin receptor B2
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BIRC3 baculoviral IAP repeat containing 3
C14ORF79 chromosome 14 open reading frame 79
CCL27 chemokine (C-C motif) ligand 27
CCR2 chemokine (C-C motif) receptor 2
CD22 CD22 molecule
CD80 CD80 molecule
CDHR2 cadherin-related family member 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRM3 cholinergic receptor, muscarinic 3
CLEC1A C-type lectin domain family 1, member A
CLIC2 chloride intracellular channel 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF1 colony stimulating factor 1 (macrophage)
CYTH1 cytohesin 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DFNB31 deafness, autosomal recessive 31
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOC2B double C2-like domains, beta
DUSP4 dual specificity phosphatase 4
ECE1 endothelin converting enzyme 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMILIN2 elastin microfibril interfacer 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETAA1 Ewing tumor-associated antigen 1
ETV5 ets variant 5
FGF22 fibroblast growth factor 22
FLOT1 flotillin 1
FZD5 frizzled class receptor 5
GADD45B growth arrest and DNA-damage-inducible, beta
HCAR3 hydroxycarboxylic acid receptor 3
ICAM1 intercellular adhesion molecule 1
IFI6 interferon, alpha-inducible protein 6
IL1RN interleukin 1 receptor antagonist
IL6ST interleukin 6 signal transducer
INHBE inhibin, beta E
ITGA7 integrin, alpha 7
ITGB6 integrin, beta 6
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA1109 KIAA1109
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LOC157562 uncharacterized LOC157562
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL2 muscleblind-like splicing regulator 2
MCPH1 microcephalin 1
MON2 MON2 homolog (S. cerevisiae)
MR1 major histocompatibility complex, class I-related
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL3 NIPA-like domain containing 3
NOTCH4 notch 4
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUPR1 nuclear protein, transcriptional regulator, 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PER1 period circadian clock 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRB3 proline-rich protein BstNI subfamily 3
PRKCI protein kinase C, iota
PSG4 pregnancy specific beta-1-glycoprotein 4
RB1 retinoblastoma 1
RBBP9 retinoblastoma binding protein 9
RND1 Rho family GTPase 1
RNF32 ring finger protein 32
SAMD4B sterile alpha motif domain containing 4B
SERHL2 serine hydrolase-like 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SKIL SKI-like proto-oncogene
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOGA1 suppressor of glucose, autophagy associated 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STC1 stanniocalcin 1
STMN3 stathmin-like 3
TIMP3 TIMP metallopeptidase inhibitor 3
TM4SF1 transmembrane 4 L six family member 1
TM4SF20 transmembrane 4 L six family member 20
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRIB3 tribbles pseudokinase 3
TSC22D2 TSC22 domain family, member 2
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WDR62 WD repeat domain 62
ZFAND5 zinc finger, AN1-type domain 5
ZNF304 zinc finger protein 304
ZXDB zinc finger, X-linked, duplicated B
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADGRE1 adhesion G protein-coupled receptor E1
ADGRG2 adhesion G protein-coupled receptor G2
AKAP5 A kinase (PRKA) anchor protein 5
ALPK1 alpha-kinase 1
ASIC3 acid sensing (proton gated) ion channel 3
ATG10 autophagy related 10
ATP10D ATPase, class V, type 10D
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BIRC7 baculoviral IAP repeat containing 7
C5AR1 complement component 5a receptor 1
CCDC134 coiled-coil domain containing 134
CD3D CD3d molecule, delta (CD3-TCR complex)
CDK18 cyclin-dependent kinase 18
CDO1 cysteine dioxygenase type 1
CEND1 cell cycle exit and neuronal differentiation 1
CNPY4 canopy FGF signaling regulator 4
CPA4 carboxypeptidase A4
CPNE7 copine VII
CXXC4 CXXC finger protein 4
DAO D-amino-acid oxidase
DEPDC5 DEP domain containing 5
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNASE1L3 deoxyribonuclease I-like 3
DOK2 docking protein 2, 56kDa
EGF epidermal growth factor
ETV7 ets variant 7
EXO5 exonuclease 5
FAM110B family with sequence similarity 110, member B
FBXW12 F-box and WD repeat domain containing 12
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALR2 galanin receptor 2
GGTLC1 gamma-glutamyltransferase light chain 1
GLDC glycine dehydrogenase (decarboxylating)
GLRA1 glycine receptor, alpha 1
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR176 G protein-coupled receptor 176
HIST1H2BM histone cluster 1, H2bm
HOXA4 homeobox A4
HOXC8 homeobox C8
HOXD11 homeobox D11
HYAL1 hyaluronoglucosaminidase 1
IFNA17 interferon, alpha 17
IHH indian hedgehog
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL22 interleukin 22
INO80D INO80 complex subunit D
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JAM3 junctional adhesion molecule 3
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD17 potassium channel tetramerization domain containing 17
KLHL25 kelch-like family member 25
LOC729164 hCG1732469
LOXL3 lysyl oxidase-like 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
LZTS3 leucine zipper, putative tumor suppressor family member 3
MOB3B MOB kinase activator 3B
MYOZ3 myozenin 3
NNAT neuronatin
NPY4R neuropeptide Y receptor Y4
NT5DC3 5'-nucleotidase domain containing 3
NYNRIN NYN domain and retroviral integrase containing
PHEX phosphate regulating endopeptidase homolog, X-linked
PLCD1 phospholipase C, delta 1
PWAR5 Prader Willi/Angelman region RNA 5
QPCT glutaminyl-peptide cyclotransferase
RAB40AL RAB40A, member RAS oncogene family-like
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF126P1 ring finger protein 126 pseudogene 1
SLC22A14 solute carrier family 22, member 14
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLN sarcolipin
SPRR1B small proline-rich protein 1B
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STIM1 stromal interaction molecule 1
SYNC syncoilin, intermediate filament protein
TAOK1 TAO kinase 1
TARP TCR gamma alternate reading frame protein
TBKBP1 TBK1 binding protein 1
TBL1Y transducin (beta)-like 1, Y-linked
TFDP3 transcription factor Dp family, member 3
TFF2 trefoil factor 2
TGFBR3 transforming growth factor, beta receptor III
TMEM53 transmembrane protein 53
TMPRSS4 transmembrane protease, serine 4
TRAIP TRAF interacting protein
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBOX5 U-box domain containing 5
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VPS9D1 VPS9 domain containing 1
ZFHX4 zinc finger homeobox 4
ZNF219 zinc finger protein 219
ZNF280A zinc finger protein 280A
ZNF442 zinc finger protein 442
ZNF747 zinc finger protein 747