benzamil-3738 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the benzamil-3738 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACPP acid phosphatase, prostate
ACTC1 actin, alpha, cardiac muscle 1
ACVR2B activin A receptor, type IIB
ADCY2 adenylate cyclase 2 (brain)
ADD2 adducin 2 (beta)
AKAP4 A kinase (PRKA) anchor protein 4
ANKLE2 ankyrin repeat and LEM domain containing 2
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOB apolipoprotein B
APOL2 apolipoprotein L, 2
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
AR androgen receptor
ARSA arylsulfatase A
ARTN artemin
BBC3 BCL2 binding component 3
C17ORF59 chromosome 17 open reading frame 59
CA5B carbonic anhydrase VB, mitochondrial
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CDKL3 cyclin-dependent kinase-like 3
CDRT1 CMT1A duplicated region transcript 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEP152 centrosomal protein 152kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNTD2 cyclin N-terminal domain containing 2
COPE coatomer protein complex, subunit epsilon
CREB3L1 cAMP responsive element binding protein 3-like 1
DCAKD dephospho-CoA kinase domain containing
DKFZP434C153 DKFZP434C153 protein
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DSCAM Down syndrome cell adhesion molecule
FAM212B family with sequence similarity 212, member B
FRY furry homolog (Drosophila)
GFER growth factor, augmenter of liver regeneration
GOLGA2P5 golgin A2 pseudogene 5
HAL histidine ammonia-lyase
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HIST1H4B histone cluster 1, H4b
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IGFBP1 insulin-like growth factor binding protein 1
KLF4 Kruppel-like factor 4 (gut)
KLHL24 kelch-like family member 24
L1CAM L1 cell adhesion molecule
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MED25 mediator complex subunit 25
MEF2D myocyte enhancer factor 2D
METTL7A methyltransferase like 7A
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIER2 mesoderm induction early response 1, family member 2
MST1 macrophage stimulating 1
NCOA2 nuclear receptor coactivator 2
NCOR2 nuclear receptor corepressor 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUPR1 nuclear protein, transcriptional regulator, 1
PCDHB13 protocadherin beta 13
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE4D phosphodiesterase 4D, cAMP-specific
PHF1 PHD finger protein 1
PIGR polymeric immunoglobulin receptor
PLCL2 phospholipase C-like 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PLSCR4 phospholipid scramblase 4
PLXNB1 plexin B1
POLL polymerase (DNA directed), lambda
POU2F2 POU class 2 homeobox 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRDM14 PR domain containing 14
PRLR prolactin receptor
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RBMS3 RNA binding motif, single stranded interacting protein 3
RGS4 regulator of G-protein signaling 4
RNASE4 ribonuclease, RNase A family, 4
RPL18 ribosomal protein L18
RUNX1 runt-related transcription factor 1
SELPLG selectin P ligand
SENP5 SUMO1/sentrin specific peptidase 5
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SMAD5-AS1 SMAD5 antisense RNA 1
SMIM14 small integral membrane protein 14
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SPTAN1 spectrin, alpha, non-erythrocytic 1
STON1 stonin 1
TAPBPL TAP binding protein-like
TBC1D29 TBC1 domain family, member 29
TBX2 T-box 2
TCF20 transcription factor 20 (AR1)
TET3 tet methylcytosine dioxygenase 3
TK2 thymidine kinase 2, mitochondrial
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TTLL1 tubulin tyrosine ligase-like family member 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WNT16 wingless-type MMTV integration site family, member 16
YPEL1 yippee-like 1 (Drosophila)
ZNF287 zinc finger protein 287
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADGRB2 adhesion G protein-coupled receptor B2
AFF4 AF4/FMR2 family, member 4
AHSG alpha-2-HS-glycoprotein
AK5 adenylate kinase 5
ALPP alkaline phosphatase, placental
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAD5 ATPase family, AAA domain containing 5
BIRC7 baculoviral IAP repeat containing 7
C17ORF70 chromosome 17 open reading frame 70
C1QTNF3 C1q and tumor necrosis factor related protein 3
CAMKMT calmodulin-lysine N-methyltransferase
CCNO cyclin O
CD79B CD79b molecule, immunoglobulin-associated beta
CHRDL1 chordin-like 1
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNTN1 contactin 1
CRMP1 collapsin response mediator protein 1
CTSK cathepsin K
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYB5R2 cytochrome b5 reductase 2
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDN dendrin
DGKE diacylglycerol kinase, epsilon 64kDa
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIO3 deiodinase, iodothyronine, type III
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELL elongation factor RNA polymerase II
ERF Ets2 repressor factor
FAM63A family with sequence similarity 63, member A
FRMD1 FERM domain containing 1
FSD1 fibronectin type III and SPRY domain containing 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GID4 GID complex subunit 4
HIRA histone cell cycle regulator
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMB major histocompatibility complex, class II, DM beta
HOXA1 homeobox A1
HOXB2 homeobox B2
IDI2-AS1 IDI2 antisense RNA 1
IFI44L interferon-induced protein 44-like
IFNA14 interferon, alpha 14
KIFC3 kinesin family member C3
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LMTK1 lemur tail kinase 1
LMTK2 lemur tyrosine kinase 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MANEA mannosidase, endo-alpha
MBNL3 muscleblind-like splicing regulator 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM4 MDM4, p53 regulator
MED31 mediator complex subunit 31
MEFV Mediterranean fever
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MOB3B MOB kinase activator 3B
MRPL52 mitochondrial ribosomal protein L52
MTA2 metastasis associated 1 family, member 2
MYOZ3 myozenin 3
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NPFFR1 neuropeptide FF receptor 1
NPHP1 nephronophthisis 1 (juvenile)
OGDHL oxoglutarate dehydrogenase-like
OSGIN1 oxidative stress induced growth inhibitor 1
OSMR oncostatin M receptor
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCDHA9 protocadherin alpha 9
PODXL2 podocalyxin-like 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB36 RAB36, member RAS oncogene family
RIBC2 RIB43A domain with coiled-coils 2
RNF146 ring finger protein 146
S100A3 S100 calcium binding protein A3
SERGEF secretion regulating guanine nucleotide exchange factor
SGK2 serum/glucocorticoid regulated kinase 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC46A3 solute carrier family 46, member 3
SLITRK5 SLIT and NTRK-like family, member 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUSD4 sushi domain containing 4
TESPA1 thymocyte expressed, positive selection associated 1
THRB thyroid hormone receptor, beta
TMEM209 transmembrane protein 209
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAC T cell receptor alpha constant
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D4 TSC22 domain family, member 4
TSKU tsukushi, small leucine rich proteoglycan
TSNAXIP1 translin-associated factor X interacting protein 1
TUBA4B tubulin, alpha 4b
TWISTNB TWIST neighbor
UGT8 UDP glycosyltransferase 8
ZNF254 zinc finger protein 254
ZNF350 zinc finger protein 350
ZNF415 zinc finger protein 415
ZNF480 zinc finger protein 480
ZNF492 zinc finger protein 492
ZNF816 zinc finger protein 816