benzamil-4294 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the benzamil-4294 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE angiotensin I converting enzyme
ACSBG2 acyl-CoA synthetase bubblegum family member 2
AGFG1 ArfGAP with FG repeats 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALPK1 alpha-kinase 1
ANGPTL2 angiopoietin-like 2
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMCX4 armadillo repeat containing, X-linked 4
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP7 bone morphogenetic protein 7
C10ORF12 chromosome 10 open reading frame 12
C5AR1 complement component 5a receptor 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CADM1 cell adhesion molecule 1
CARD8 caspase recruitment domain family, member 8
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCL16 chemokine (C-C motif) ligand 16
CD22 CD22 molecule
CDK13 cyclin-dependent kinase 13
CDKL5 cyclin-dependent kinase-like 5
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CNPY4 canopy FGF signaling regulator 4
CPEB3 cytoplasmic polyadenylation element binding protein 3
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DCT dopachrome tautomerase
DMXL2 Dmx-like 2
DST dystonin
E2F5 E2F transcription factor 5, p130-binding
ELL2 elongation factor, RNA polymerase II, 2
ERAP1 endoplasmic reticulum aminopeptidase 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GDF9 growth differentiation factor 9
GJA9 gap junction protein, alpha 9, 59kDa
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GUSBP3 glucuronidase, beta pseudogene 3
HIPK2 homeodomain interacting protein kinase 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IMPG2 interphotoreceptor matrix proteoglycan 2
INSL4 insulin-like 4 (placenta)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLF4 Kruppel-like factor 4 (gut)
KLHL24 kelch-like family member 24
KRT86 keratin 86, type II
LAT2 linker for activation of T cells family, member 2
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LRRC40 leucine rich repeat containing 40
MAGIX MAGI family member, X-linked
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK8 mitogen-activated protein kinase 8
MED18 mediator complex subunit 18
MORN1 MORN repeat containing 1
MUC8 mucin 8
NF1 neurofibromin 1
NIPAL2 NIPA-like domain containing 2
NNAT neuronatin
PAWR PRKC, apoptosis, WT1, regulator
PDE5A phosphodiesterase 5A, cGMP-specific
PGK1 phosphoglycerate kinase 1
PILRA paired immunoglobin-like type 2 receptor alpha
PKP4 plakophilin 4
PLIN2 perilipin 2
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRDM14 PR domain containing 14
PRKG1 protein kinase, cGMP-dependent, type I
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRR protein tyrosine phosphatase, receptor type, R
RAB2A RAB2A, member RAS oncogene family
RBM26 RNA binding motif protein 26
SCIN scinderin
SFTPB surfactant protein B
SHOX2 short stature homeobox 2
SSX3 synovial sarcoma, X breakpoint 3
STAB1 stabilin 1
STK38 serine/threonine kinase 38
SUGP1 SURP and G patch domain containing 1
SYT2 synaptotagmin II
TCF4 transcription factor 4
TMEM246 transmembrane protein 246
TMPRSS15 transmembrane protease, serine 15
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TSPAN9 tetraspanin 9
TWF1 twinfilin actin binding protein 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VDAC3 voltage-dependent anion channel 3
YIPF4 Yip1 domain family, member 4
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFP64 ZFP64 zinc finger protein
ZNF117 zinc finger protein 117

decreased expression

Symbol Name
AATF apoptosis antagonizing transcription factor
ABHD8 abhydrolase domain containing 8
ADAP2 ArfGAP with dual PH domains 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARRB2 arrestin, beta 2
ASCC2 activating signal cointegrator 1 complex subunit 2
ASIC3 acid sensing (proton gated) ion channel 3
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B9D2 B9 protein domain 2
C11ORF21 chromosome 11 open reading frame 21
C17ORF80 chromosome 17 open reading frame 80
CA5BP1 carbonic anhydrase VB pseudogene 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC132 coiled-coil domain containing 132
CCDC71 coiled-coil domain containing 71
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CUZD1 CUB and zona pellucida-like domains 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DMBT1 deleted in malignant brain tumors 1
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DRAM1 DNA-damage regulated autophagy modulator 1
EGLN3 egl-9 family hypoxia-inducible factor 3
ERCC4 excision repair cross-complementation group 4
ETV6 ets variant 6
EYA4 EYA transcriptional coactivator and phosphatase 4
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL15 F-box and leucine-rich repeat protein 15
FBXO22 F-box protein 22
GAS8 growth arrest-specific 8
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GMPR guanosine monophosphate reductase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HDAC11 histone deacetylase 11
HOXC13 homeobox C13
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HYOU1 hypoxia up-regulated 1
IL22 interleukin 22
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KIAA0319L KIAA0319-like
KIF13A kinesin family member 13A
KLHL25 kelch-like family member 25
KLHL36 kelch-like family member 36
LIMS2 LIM and senescent cell antigen-like domains 2
LINC00260 long intergenic non-protein coding RNA 260
LRP2 low density lipoprotein receptor-related protein 2
LRP3 low density lipoprotein receptor-related protein 3
LRRC61 leucine rich repeat containing 61
LRRK1 leucine-rich repeat kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEA5 melanoma antigen family A5
MED15 mediator complex subunit 15
MMP3 matrix metallopeptidase 3
MOB3B MOB kinase activator 3B
MUC3B mucin 3B, cell surface associated
MX1 MX dynamin-like GTPase 1
NISCH nischarin
NOL6 nucleolar protein 6 (RNA-associated)
NR1H3 nuclear receptor subfamily 1, group H, member 3
NSUN6 NOP2/Sun domain family, member 6
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARP3 poly (ADP-ribose) polymerase family, member 3
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PEX26 peroxisomal biogenesis factor 26
PLAC8 placenta-specific 8
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
POLL polymerase (DNA directed), lambda
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTK6 protein tyrosine kinase 6
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBM14 RNA binding motif protein 14
RBM42 RNA binding motif protein 42
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCN1B sodium channel, voltage gated, type I beta subunit
SH3GL1 SH3-domain GRB2-like 1
SLC46A3 solute carrier family 46, member 3
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX21 SRY (sex determining region Y)-box 21
TEAD4 TEA domain family member 4
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM132A transmembrane protein 132A
TNS2 tensin 2
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
USP20 ubiquitin specific peptidase 20
WDR46 WD repeat domain 46
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H3 zinc finger CCCH-type containing 3
ZNF10 zinc finger protein 10
ZNF37BP zinc finger protein 37B, pseudogene
ZNF573 zinc finger protein 573
ZNF768 zinc finger protein 768