| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the benzbromarone-1291 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADAM17 | ADAM metallopeptidase domain 17 |
| AEN | apoptosis enhancing nuclease |
| ANAPC5 | anaphase promoting complex subunit 5 |
| ATP13A3 | ATPase type 13A3 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CDV3 | CDV3 homolog (mouse) |
| CLIC4 | chloride intracellular channel 4 |
| COPA | coatomer protein complex, subunit alpha |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EMC1 | ER membrane protein complex subunit 1 |
| ERLIN1 | ER lipid raft associated 1 |
| FBXW11 | F-box and WD repeat domain containing 11 |
| FCAR | Fc fragment of IgA receptor |
| FLOT1 | flotillin 1 |
| FNDC3A | fibronectin type III domain containing 3A |
| FOXJ3 | forkhead box J3 |
| GK | glycerol kinase |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GTF2I | general transcription factor IIi |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HOXA10 | homeobox A10 |
| IL1RAP | interleukin 1 receptor accessory protein |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA1033 | KIAA1033 |
| LINC00094 | long intergenic non-protein coding RNA 94 |
| LMAN1 | lectin, mannose-binding, 1 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAX | MYC associated factor X |
| MCL1 | myeloid cell leukemia 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED28 | mediator complex subunit 28 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MTAP | methylthioadenosine phosphorylase |
| NFYA | nuclear transcription factor Y, alpha |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PLK4 | polo-like kinase 4 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| RAB6A | RAB6A, member RAS oncogene family |
| RCAN1 | regulator of calcineurin 1 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| SC5D | sterol-C5-desaturase |
| SCAMP1 | secretory carrier membrane protein 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIRT5 | sirtuin 5 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SNX16 | sorting nexin 16 |
| SRR | serine racemase |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STIP1 | stress-induced phosphoprotein 1 |
| STX16 | syntaxin 16 |
| SYNC | syncoilin, intermediate filament protein |
| TANK | TRAF family member-associated NFKB activator |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEX15 | testis expressed 15 |
| TLK1 | tousled-like kinase 1 |
| TM2D1 | TM2 domain containing 1 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TMEM259 | transmembrane protein 259 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TPD52L1 | tumor protein D52-like 1 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TWISTNB | TWIST neighbor |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| UTRN | utrophin |
| VAMP3 | vesicle-associated membrane protein 3 |
| WSB1 | WD repeat and SOCS box containing 1 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| YY1 | YY1 transcription factor |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMYM6 | zinc finger, MYM-type 6 |
| Symbol | Name |
|---|---|
| ACO1 | aconitase 1, soluble |
| ACVR2B | activin A receptor, type IIB |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARMC6 | armadillo repeat containing 6 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BTBD18 | BTB (POZ) domain containing 18 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCNT1 | cyclin T1 |
| CD82 | CD82 molecule |
| CHD8 | chromodomain helicase DNA binding protein 8 |
| CHMP1A | charged multivesicular body protein 1A |
| CHMP7 | charged multivesicular body protein 7 |
| CLASRP | CLK4-associating serine/arginine rich protein |
| CLSTN1 | calsyntenin 1 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| CTPS2 | CTP synthase 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEAF1 | DEAF1 transcription factor |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DYM | dymeclin |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| EGR2 | early growth response 2 |
| EMC9 | ER membrane protein complex subunit 9 |
| EVL | Enah/Vasp-like |
| FAM222B | family with sequence similarity 222, member B |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FHOD1 | formin homology 2 domain containing 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HHLA3 | HERV-H LTR-associating 3 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IL17RA | interleukin 17 receptor A |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) |
| JUP | junction plakoglobin |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KIF1B | kinesin family member 1B |
| LMNB2 | lamin B2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MCMBP | minichromosome maintenance complex binding protein |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MICALL2 | MICAL-like 2 |
| MXD3 | MAX dimerization protein 3 |
| NBEAL2 | neurobeachin-like 2 |
| NRBP1 | nuclear receptor binding protein 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NUCB1 | nucleobindin 1 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POLM | polymerase (DNA directed), mu |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRAF2 | PRA1 domain family, member 2 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPA4 | replication protein A4, 30kDa |
| SCAMP4 | secretory carrier membrane protein 4 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SREK1IP1 | SREK1-interacting protein 1 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TAOK1 | TAO kinase 1 |
| THEM6 | thioesterase superfamily member 6 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TPCN1 | two pore segment channel 1 |
| TRIM66 | tripartite motif containing 66 |
| TSPAN32 | tetraspanin 32 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WBSCR16 | Williams-Beuren syndrome chromosome region 16 |
| WDR7 | WD repeat domain 7 |
| XPC | xeroderma pigmentosum, complementation group C |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF329 | zinc finger protein 329 |
| ZNF345 | zinc finger protein 345 |
| ZNF669 | zinc finger protein 669 |
