| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the benzbromarone-5015 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ACRV1 | acrosomal vesicle protein 1 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| ARTN | artemin |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BMP8B | bone morphogenetic protein 8b |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD300C | CD300c molecule |
| CDIP1 | cell death-inducing p53 target 1 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 |
| CPB2 | carboxypeptidase B2 (plasma) |
| EDNRA | endothelin receptor type A |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| EHD2 | EH-domain containing 2 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| GK | glycerol kinase |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPM6A | glycoprotein M6A |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GYG2 | glycogenin 2 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HIST1H4D | histone cluster 1, H4d |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFNA14 | interferon, alpha 14 |
| IGF1R | insulin-like growth factor 1 receptor |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| ING1 | inhibitor of growth family, member 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLHL25 | kelch-like family member 25 |
| KRT16 | keratin 16, type I |
| LAMB4 | laminin, beta 4 |
| LIMK2 | LIM domain kinase 2 |
| LMF1 | lipase maturation factor 1 |
| LOC644450 | uncharacterized LOC644450 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NEK11 | NIMA-related kinase 11 |
| NF1 | neurofibromin 1 |
| NKX2-5 | NK2 homeobox 5 |
| NOP16 | NOP16 nucleolar protein |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OR2W1 | olfactory receptor, family 2, subfamily W, member 1 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PIDD1 | p53-induced death domain protein 1 |
| PMEL | premelanosome protein |
| POLL | polymerase (DNA directed), lambda |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RAI2 | retinoic acid induced 2 |
| RARG | retinoic acid receptor, gamma |
| RGS10 | regulator of G-protein signaling 10 |
| RPS2 | ribosomal protein S2 |
| RUSC2 | RUN and SH3 domain containing 2 |
| S100A8 | S100 calcium binding protein A8 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SP140L | SP140 nuclear body protein-like |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SPON1 | spondin 1, extracellular matrix protein |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SSH3 | slingshot protein phosphatase 3 |
| STC1 | stanniocalcin 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TDRD12 | tudor domain containing 12 |
| TG | thyroglobulin |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| THRB | thyroid hormone receptor, beta |
| TLR5 | toll-like receptor 5 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMC6 | transmembrane channel-like 6 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UBOX5 | U-box domain containing 5 |
| VASH2 | vasohibin 2 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VPS9D1 | VPS9 domain containing 1 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| YIPF4 | Yip1 domain family, member 4 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARRB1 | arrestin, beta 1 |
| ARSB | arylsulfatase B |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC68 | coiled-coil domain containing 68 |
| CD302 | CD302 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CDON | cell adhesion associated, oncogene regulated |
| CIDEC | cell death-inducing DFFA-like effector c |
| CORO7 | coronin 7 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CPTP | ceramide-1-phosphate transfer protein |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DSCAM | Down syndrome cell adhesion molecule |
| DYSF | dysferlin |
| EN2 | engrailed homeobox 2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM169A | family with sequence similarity 169, member A |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HCFC1 | host cell factor C1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IPO8 | importin 8 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRX4 | iroquois homeobox 4 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KIAA0319L | KIAA0319-like |
| LAMB3 | laminin, beta 3 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MEFV | Mediterranean fever |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MMP2 | matrix metallopeptidase 2 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MVP | major vault protein |
| NME5 | NME/NM23 family member 5 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PCDHA6 | protocadherin alpha 6 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKCE | protein kinase C, epsilon |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| QSER1 | glutamine and serine rich 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB30 | RAB30, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPAP1 | RNA polymerase II associated protein 1 |
| S100A4 | S100 calcium binding protein A4 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SREK1IP1 | SREK1-interacting protein 1 |
| SRPX | sushi-repeat containing protein, X-linked |
| STIM1 | stromal interaction molecule 1 |
| TCTN2 | tectonic family member 2 |
| TMC7 | transmembrane channel-like 7 |
| TMEM209 | transmembrane protein 209 |
| TMEM242 | transmembrane protein 242 |
| TMEM45A | transmembrane protein 45A |
| TRIM21 | tripartite motif containing 21 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TUBA4B | tubulin, alpha 4b |
| TWF2 | twinfilin actin binding protein 2 |
| UBQLN4 | ubiquilin 4 |
| VGF | VGF nerve growth factor inducible |
| WDR19 | WD repeat domain 19 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF205 | zinc finger protein 205 |
| ZNF35 | zinc finger protein 35 |
| ZNF350 | zinc finger protein 350 |
| ZNF551 | zinc finger protein 551 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
