| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the benzbromarone-6669 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| AAK1 | AP2 associated kinase 1 |
| ABAT | 4-aminobutyrate aminotransferase |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AK5 | adenylate kinase 5 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL2 | B-cell CLL/lymphoma 2 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CADM1 | cell adhesion molecule 1 |
| CALB2 | calbindin 2 |
| CALCR | calcitonin receptor |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCK | cholecystokinin |
| CCNO | cyclin O |
| CLTC | clathrin, heavy chain (Hc) |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP11B2 | cytochrome P450, family 11, subfamily B, polypeptide 2 |
| DBF4B | DBF4 zinc finger B |
| DCN | decorin |
| DDX4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| ELL | elongation factor RNA polymerase II |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM46C | family with sequence similarity 46, member C |
| FAM63A | family with sequence similarity 63, member A |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| FXYD1 | FXYD domain containing ion transport regulator 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAST | gastrin |
| GOLGA8A | golgin A8 family, member A |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HOXB7 | homeobox B7 |
| HOXC5 | homeobox C5 |
| HRH4 | histamine receptor H4 |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IDS | iduronate 2-sulfatase |
| IRS4 | insulin receptor substrate 4 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KLF12 | Kruppel-like factor 12 |
| KLF13 | Kruppel-like factor 13 |
| LCAT | lecithin-cholesterol acyltransferase |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MED25 | mediator complex subunit 25 |
| METTL7A | methyltransferase like 7A |
| MFAP3L | microfibrillar-associated protein 3-like |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MIP | major intrinsic protein of lens fiber |
| MTCP1 | mature T-cell proliferation 1 |
| NEO1 | neogenin 1 |
| NNMT | nicotinamide N-methyltransferase |
| NRXN3 | neurexin 3 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASAL2 | RAS protein activator like 2 |
| RPL13 | ribosomal protein L13 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCARB1 | scavenger receptor class B, member 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TAOK2 | TAO kinase 2 |
| TBX6 | T-box 6 |
| TCP10 | t-complex 10 |
| TEX13A | testis expressed 13A |
| TNPO2 | transportin 2 |
| TRIM29 | tripartite motif containing 29 |
| TYMP | thymidine phosphorylase |
| UBXN1 | UBX domain protein 1 |
| USP22 | ubiquitin specific peptidase 22 |
| USP29 | ubiquitin specific peptidase 29 |
| VAMP5 | vesicle-associated membrane protein 5 |
| VNN3 | vanin 3 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WDR55 | WD repeat domain 55 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZNF268 | zinc finger protein 268 |
| ZNF688 | zinc finger protein 688 |
| ZNF778 | zinc finger protein 778 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| AFAP1 | actin filament associated protein 1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| APOL6 | apolipoprotein L, 6 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC132 | coiled-coil domain containing 132 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CFAP69 | cilia and flagella associated protein 69 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CST1 | cystatin SN |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYBRD1 | cytochrome b reductase 1 |
| DBR1 | debranching RNA lariats 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DNM3 | dynamin 3 |
| EDAR | ectodysplasin A receptor |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM204A | family with sequence similarity 204, member A |
| FBRS | fibrosin |
| FBXO2 | F-box protein 2 |
| FKBP5 | FK506 binding protein 5 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPATCH3 | G patch domain containing 3 |
| GPC3 | glypican 3 |
| HAMP | hepcidin antimicrobial peptide |
| HDAC11 | histone deacetylase 11 |
| HDAC7 | histone deacetylase 7 |
| HIST1H2AK | histone cluster 1, H2ak |
| HOXC8 | homeobox C8 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFNA14 | interferon, alpha 14 |
| IFT140 | intraflagellar transport 140 |
| IL22 | interleukin 22 |
| ITGB7 | integrin, beta 7 |
| ITK | IL2-inducible T-cell kinase |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIAA1107 | KIAA1107 |
| KRT20 | keratin 20, type I |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC257152 | uncharacterized LOC257152 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYRM9 | LYR motif containing 9 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MDFI | MyoD family inhibitor |
| MTMR6 | myotubularin related protein 6 |
| MX1 | MX dynamin-like GTPase 1 |
| NEK11 | NIMA-related kinase 11 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PER1 | period circadian clock 1 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIP | prolactin-induced protein |
| PLD2 | phospholipase D2 |
| POM121 | POM121 transmembrane nucleoporin |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| SEPP1 | selenoprotein P, plasma, 1 |
| SIX3 | SIX homeobox 3 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCTN2 | tectonic family member 2 |
| TENM1 | teneurin transmembrane protein 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TMEM2 | transmembrane protein 2 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRABD | TraB domain containing |
| TSC1 | tuberous sclerosis 1 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| UGT8 | UDP glycosyltransferase 8 |
| USP20 | ubiquitin specific peptidase 20 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF219 | zinc finger protein 219 |
| ZNF222 | zinc finger protein 222 |
