benzethonium chloride-6070 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the benzethonium chloride-6070 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ATF3 activating transcription factor 3
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BCL6 B-cell CLL/lymphoma 6
BDKRB2 bradykinin receptor B2
BHLHE40 basic helix-loop-helix family, member e40
C1ORF54 chromosome 1 open reading frame 54
CA9 carbonic anhydrase IX
CCNG2 cyclin G2
CDC25C cell division cycle 25C
CDRT1 CMT1A duplicated region transcript 1
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHM choroideremia (Rab escort protein 1)
CLCN6 chloride channel, voltage-sensitive 6
CLGN calmegin
CNGA1 cyclic nucleotide gated channel alpha 1
CT55 cancer/testis antigen 55
CT62 cancer/testis antigen 62
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERO1LB ERO1-like beta (S. cerevisiae)
FAM63B family with sequence similarity 63, member B
FCAR Fc fragment of IgA receptor
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GEM GTP binding protein overexpressed in skeletal muscle
GPER1 G protein-coupled estrogen receptor 1
HHAT hedgehog acyltransferase
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IL21R interleukin 21 receptor
INHBE inhibin, beta E
INSIG1 insulin induced gene 1
IPW imprinted in Prader-Willi syndrome (non-protein coding)
IRS2 insulin receptor substrate 2
KIAA1107 KIAA1107
KLF2 Kruppel-like factor 2
KLHL24 kelch-like family member 24
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MARS methionyl-tRNA synthetase
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1X metallothionein 1X
MT2A metallothionein 2A
MUC3B mucin 3B, cell surface associated
NAT6 N-acetyltransferase 6 (GCN5-related)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUPR1 nuclear protein, transcriptional regulator, 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKP2 plakophilin 2
PNRC1 proline-rich nuclear receptor coactivator 1
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRJ protein tyrosine phosphatase, receptor type, J
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAP1GAP RAP1 GTPase activating protein
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RND1 Rho family GTPase 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A8 S100 calcium binding protein A8
SERHL2 serine hydrolase-like 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMIM14 small integral membrane protein 14
SPTBN1 spectrin, beta, non-erythrocytic 1
TBC1D19 TBC1 domain family, member 19
TBX3 T-box 3
TCF25 transcription factor 25 (basic helix-loop-helix)
TENM1 teneurin transmembrane protein 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRBC1 T cell receptor beta constant 1
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
TTC22 tetratricopeptide repeat domain 22
TXNIP thioredoxin interacting protein
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
ULBP1 UL16 binding protein 1
UNC5B unc-5 homolog B (C. elegans)
USP29 ubiquitin specific peptidase 29
VCAN versican
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WNT6 wingless-type MMTV integration site family, member 6

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTN4 actinin, alpha 4
AEN apoptosis enhancing nuclease
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALS2CL ALS2 C-terminal like
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC4 armadillo repeat containing 4
BAHCC1 BAH domain and coiled-coil containing 1
BCL9 B-cell CLL/lymphoma 9
BMP4 bone morphogenetic protein 4
BTBD2 BTB (POZ) domain containing 2
C11ORF80 chromosome 11 open reading frame 80
C2ORF44 chromosome 2 open reading frame 44
C5ORF45 chromosome 5 open reading frame 45
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN15 calpain 15
CCDC85C coiled-coil domain containing 85C
CIC capicua transcriptional repressor
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNR2 cannabinoid receptor 2 (macrophage)
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRIP1 cysteine-rich protein 1 (intestinal)
DGAT1 diacylglycerol O-acyltransferase 1
DIXDC1 DIX domain containing 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA3 ephrin-A3
EGLN3 egl-9 family hypoxia-inducible factor 3
EPHB3 EPH receptor B3
FAM188A family with sequence similarity 188, member A
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAMT guanidinoacetate N-methyltransferase
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GMPR guanosine monophosphate reductase
GPATCH3 G patch domain containing 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRWD1 glutamate-rich WD repeat containing 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AL histone cluster 1, H2al
HIST1H4E histone cluster 1, H4e
HOXA4 homeobox A4
IDI2-AS1 IDI2 antisense RNA 1
IL22 interleukin 22
ITPKB inositol-trisphosphate 3-kinase B
LARP6 La ribonucleoprotein domain family, member 6
LIN7A lin-7 homolog A (C. elegans)
LRRC20 leucine rich repeat containing 20
LRRC61 leucine rich repeat containing 61
MAP7D1 MAP7 domain containing 1
MAST3 microtubule associated serine/threonine kinase 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUC3A mucin 3A, cell surface associated
MYOZ3 myozenin 3
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NFE2L3 nuclear factor, erythroid 2-like 3
NFS1 NFS1 cysteine desulfurase
NOL10 nucleolar protein 10
NT5DC3 5'-nucleotidase domain containing 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUD3 OTU deubiquitinase 3
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PITX2 paired-like homeodomain 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPARG peroxisome proliferator-activated receptor gamma
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBM14 RNA binding motif protein 14
REEP1 receptor accessory protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC12A8 solute carrier family 12, member 8
SLC17A2 solute carrier family 17, member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNHG3 small nucleolar RNA host gene 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAOK1 TAO kinase 1
TDRD1 tudor domain containing 1
TMCC2 transmembrane and coiled-coil domain family 2
TMEM120B transmembrane protein 120B
TMEM254 transmembrane protein 254
TNRC6B trinucleotide repeat containing 6B
TPCN1 two pore segment channel 1
TRIM21 tripartite motif containing 21
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
XAB2 XPA binding protein 2
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF324 zinc finger protein 324
ZNF480 zinc finger protein 480
ZNF551 zinc finger protein 551
ZNF668 zinc finger protein 668