| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the benzocaine-2822 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| ALS2CL | ALS2 C-terminal like |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARTN | artemin |
| ATG3 | autophagy related 3 |
| ATM | ATM serine/threonine kinase |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C3 | complement component 3 |
| CABIN1 | calcineurin binding protein 1 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD8A | CD8a molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CGA | glycoprotein hormones, alpha polypeptide |
| COL18A1 | collagen, type XVIII, alpha 1 |
| COL5A2 | collagen, type V, alpha 2 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DESI2 | desumoylating isopeptidase 2 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DICER1 | dicer 1, ribonuclease type III |
| DIO2 | deiodinase, iodothyronine, type II |
| DSC2 | desmocollin 2 |
| DTNA | dystrobrevin, alpha |
| EMC1 | ER membrane protein complex subunit 1 |
| EML3 | echinoderm microtubule associated protein like 3 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ESR1 | estrogen receptor 1 |
| FAM46C | family with sequence similarity 46, member C |
| FGF2 | fibroblast growth factor 2 (basic) |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GK | glycerol kinase |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IL1R1 | interleukin 1 receptor, type I |
| ITGA6 | integrin, alpha 6 |
| KIAA0319L | KIAA0319-like |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT17 | keratin 17, type I |
| LDLR | low density lipoprotein receptor |
| LRRC8B | leucine rich repeat containing 8 family, member B |
| MERTK | MER proto-oncogene, tyrosine kinase |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NF1 | neurofibromin 1 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPAS3 | neuronal PAS domain protein 3 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| ONECUT2 | one cut homeobox 2 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POFUT1 | protein O-fucosyltransferase 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRDX2 | peroxiredoxin 2 |
| PRF1 | perforin 1 (pore forming protein) |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTRF | polymerase I and transcript release factor |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RANBP1 | RAN binding protein 1 |
| RASA3 | RAS p21 protein activator 3 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RPL35A | ribosomal protein L35a |
| RXRB | retinoid X receptor, beta |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SFXN1 | sideroflexin 1 |
| SIRT4 | sirtuin 4 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| STAB2 | stabilin 2 |
| STX16 | syntaxin 16 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TAPBP | TAP binding protein (tapasin) |
| TBX5 | T-box 5 |
| TMC6 | transmembrane channel-like 6 |
| TRAF2 | TNF receptor-associated factor 2 |
| TREM2 | triggering receptor expressed on myeloid cells 2 |
| TSC2 | tuberous sclerosis 2 |
| TTC23 | tetratricopeptide repeat domain 23 |
| UBQLN4 | ubiquilin 4 |
| USP32 | ubiquitin specific peptidase 32 |
| WWC2 | WW and C2 domain containing 2 |
| YIPF4 | Yip1 domain family, member 4 |
| ZMYM2 | zinc finger, MYM-type 2 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| APOD | apolipoprotein D |
| ARMC4 | armadillo repeat containing 4 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C5AR2 | complement component 5a receptor 2 |
| CARTPT | CART prepropeptide |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CDON | cell adhesion associated, oncogene regulated |
| CES3 | carboxylesterase 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| CFL1 | cofilin 1 (non-muscle) |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CIC | capicua transcriptional repressor |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP2 | dual specificity phosphatase 2 |
| DYSF | dysferlin |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
| FAM212B | family with sequence similarity 212, member B |
| FAM53B | family with sequence similarity 53, member B |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GAS2 | growth arrest-specific 2 |
| GK2 | glycerol kinase 2 |
| GPR22 | G protein-coupled receptor 22 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| LOC257152 | uncharacterized LOC257152 |
| LOC729164 | hCG1732469 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAGEA3 | melanoma antigen family A3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCOLN3 | mucolipin 3 |
| MNT | MAX network transcriptional repressor |
| MX1 | MX dynamin-like GTPase 1 |
| NCALD | neurocalcin delta |
| NDE1 | nudE neurodevelopment protein 1 |
| NEK11 | NIMA-related kinase 11 |
| OLFML3 | olfactomedin-like 3 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PAX9 | paired box 9 |
| PICK1 | protein interacting with PRKCA 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRKCE | protein kinase C, epsilon |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB3A | RAB3A, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RHBDD3 | rhomboid domain containing 3 |
| RIN1 | Ras and Rab interactor 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPL21 | ribosomal protein L21 |
| RPL32 | ribosomal protein L32 |
| RPL41 | ribosomal protein L41 |
| RPS15A | ribosomal protein S15a |
| RPS24 | ribosomal protein S24 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A2 | S100 calcium binding protein A2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SDS | serine dehydratase |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBC1D22B | TBC1 domain family, member 22B |
| TCTN2 | tectonic family member 2 |
| THBS3 | thrombospondin 3 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| USB1 | U6 snRNA biogenesis 1 |
| WDR25 | WD repeat domain 25 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZIC3 | Zic family member 3 |
| ZNF639 | zinc finger protein 639 |
| ZNF862 | zinc finger protein 862 |
