| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the benzocaine-4224 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGB | androglobin |
| ADRA1A | adrenoceptor alpha 1A |
| ADRB1 | adrenoceptor beta 1 |
| AGTR1 | angiotensin II receptor, type 1 |
| AGXT | alanine-glyoxylate aminotransferase |
| AIRE | autoimmune regulator |
| ANGPT4 | angiopoietin 4 |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| APOE | apolipoprotein E |
| AQP4 | aquaporin 4 |
| BMP7 | bone morphogenetic protein 7 |
| BTBD7 | BTB (POZ) domain containing 7 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CCL24 | chemokine (C-C motif) ligand 24 |
| CCR4 | chemokine (C-C motif) receptor 4 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 |
| CPN1 | carboxypeptidase N, polypeptide 1 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CRH | corticotropin releasing hormone |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DAPK2 | death-associated protein kinase 2 |
| DENND1C | DENN/MADD domain containing 1C |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FGA | fibrinogen alpha chain |
| FOLR1 | folate receptor 1 (adult) |
| GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GLI2 | GLI family zinc finger 2 |
| GPX3 | glutathione peroxidase 3 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRIK3 | glutamate receptor, ionotropic, kainate 3 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| H2AFX | H2A histone family, member X |
| IL5RA | interleukin 5 receptor, alpha |
| INADL | InaD-like (Drosophila) |
| IQCK | IQ motif containing K |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNJ13 | potassium channel, inwardly rectifying subfamily J, member 13 |
| KIAA0125 | KIAA0125 |
| KRTAP5-9 | keratin associated protein 5-9 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LY6G6D | lymphocyte antigen 6 complex, locus G6D |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 |
| LZTS1 | leucine zipper, putative tumor suppressor 1 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MFAP5 | microfibrillar associated protein 5 |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| NPR1 | natriuretic peptide receptor 1 |
| OMD | osteomodulin |
| OR7E24 | olfactory receptor, family 7, subfamily E, member 24 |
| PCYT1B | phosphate cytidylyltransferase 1, choline, beta |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 |
| PLVAP | plasmalemma vesicle associated protein |
| POU1F1 | POU class 1 homeobox 1 |
| POU6F1 | POU class 6 homeobox 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRTN3 | proteinase 3 |
| PTTG2 | pituitary tumor-transforming 2 |
| PYY | peptide YY |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS16 | regulator of G-protein signaling 16 |
| SATB2 | SATB homeobox 2 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLA | Src-like-adaptor |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC2A2 | solute carrier family 2 (facilitated glucose transporter), member 2 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SPAG8 | sperm associated antigen 8 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| TAS2R3 | taste receptor, type 2, member 3 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TJP3 | tight junction protein 3 |
| TLE4 | transducin-like enhancer of split 4 |
| TRAPPC9 | trafficking protein particle complex 9 |
| TRIM2 | tripartite motif containing 2 |
| TTC12 | tetratricopeptide repeat domain 12 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF385D | zinc finger protein 385D |
| ZNRF4 | zinc and ring finger 4 |
| ZSCAN12 | zinc finger and SCAN domain containing 12 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AFF4 | AF4/FMR2 family, member 4 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BEND5 | BEN domain containing 5 |
| BMP15 | bone morphogenetic protein 15 |
| BNC1 | basonuclin 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C8A | complement component 8, alpha polypeptide |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CEP83 | centrosomal protein 83kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CHRDL1 | chordin-like 1 |
| CLDN11 | claudin 11 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CSF1R | colony stimulating factor 1 receptor |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DNM3 | dynamin 3 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EXOC6B | exocyst complex component 6B |
| FAM169A | family with sequence similarity 169, member A |
| FANCC | Fanconi anemia, complementation group C |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GID4 | GID complex subunit 4 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GMPR | guanosine monophosphate reductase |
| GPATCH2L | G patch domain containing 2-like |
| GTF2I | general transcription factor IIi |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H3F | histone cluster 1, H3f |
| HOXA1 | homeobox A1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFT54 | intraflagellar transport 54 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INCENP | inner centromere protein antigens 135/155kDa |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT86 | keratin 86, type II |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC157562 | uncharacterized LOC157562 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LY86 | lymphocyte antigen 86 |
| MANBA | mannosidase, beta A, lysosomal |
| MAPK12 | mitogen-activated protein kinase 12 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MMP13 | matrix metallopeptidase 13 |
| MRAS | muscle RAS oncogene homolog |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NAG18 | NAG18 mRNA |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PALMD | palmdelphin |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDE8B | phosphodiesterase 8B |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RRAGB | Ras-related GTP binding B |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SHROOM2 | shroom family member 2 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPIDR | scaffolding protein involved in DNA repair |
| SPRYD7 | SPRY domain containing 7 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STEAP4 | STEAP family member 4 |
| TAGLN3 | transgelin 3 |
| TEX40 | testis expressed 40 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TLR2 | toll-like receptor 2 |
| TMEM2 | transmembrane protein 2 |
| TMEM242 | transmembrane protein 242 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TXLNG | taxilin gamma |
| ZNF141 | zinc finger protein 141 |
| ZNF286A | zinc finger protein 286A |
| ZNF492 | zinc finger protein 492 |
