| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the benzocaine-4808 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| AAK1 | AP2 associated kinase 1 |
| ANGPTL2 | angiopoietin-like 2 |
| APOE | apolipoprotein E |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| BAIAP3 | BAI1-associated protein 3 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CA4 | carbonic anhydrase IV |
| CCDC64 | coiled-coil domain containing 64 |
| CD101 | CD101 molecule |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CPNE7 | copine VII |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DSG3 | desmoglein 3 |
| EFNA3 | ephrin-A3 |
| ENO3 | enolase 3 (beta, muscle) |
| EPHB6 | EPH receptor B6 |
| EPOR | erythropoietin receptor |
| EXOC7 | exocyst complex component 7 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GLP1R | glucagon-like peptide 1 receptor |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GYPB | glycophorin B (MNS blood group) |
| HBD | hemoglobin, delta |
| HDAC7 | histone deacetylase 7 |
| HOXA10 | homeobox A10 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IGL | immunoglobulin lambda locus |
| IQCE | IQ motif containing E |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KIAA0226L | KIAA0226-like |
| KLK11 | kallikrein-related peptidase 11 |
| KRT6B | keratin 6B, type II |
| KRT83 | keratin 83, type II |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MED16 | mediator complex subunit 16 |
| MMP3 | matrix metallopeptidase 3 |
| MPPE1 | metallophosphoesterase 1 |
| MTAP | methylthioadenosine phosphorylase |
| MVP | major vault protein |
| NIPAL2 | NIPA-like domain containing 2 |
| NPY4R | neuropeptide Y receptor Y4 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OPRK1 | opioid receptor, kappa 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PALM | paralemmin |
| PIPOX | pipecolic acid oxidase |
| PLXDC1 | plexin domain containing 1 |
| POLL | polymerase (DNA directed), lambda |
| POPDC3 | popeye domain containing 3 |
| PPEF1 | protein phosphatase, EF-hand calcium binding domain 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTH1R | parathyroid hormone 1 receptor |
| RBM26 | RNA binding motif protein 26 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SH3BP2 | SH3-domain binding protein 2 |
| SIRT4 | sirtuin 4 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC35E1 | solute carrier family 35, member E1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMTN | smoothelin |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SUGP1 | SURP and G patch domain containing 1 |
| TAAR3 | trace amine associated receptor 3 (gene/pseudogene) |
| TBXA2R | thromboxane A2 receptor |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMC6 | transmembrane channel-like 6 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| USP22 | ubiquitin specific peptidase 22 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| ZIM2 | zinc finger, imprinted 2 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF24 | zinc finger protein 24 |
| ZNF419 | zinc finger protein 419 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AFF4 | AF4/FMR2 family, member 4 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| B9D2 | B9 protein domain 2 |
| BLNK | B-cell linker |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEP97 | centrosomal protein 97kDa |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CXADR | coxsackie virus and adenovirus receptor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| EXO5 | exonuclease 5 |
| FAM120C | family with sequence similarity 120C |
| FAM169A | family with sequence similarity 169, member A |
| FBXO2 | F-box protein 2 |
| FGF23 | fibroblast growth factor 23 |
| GALK1 | galactokinase 1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| HHAT | hedgehog acyltransferase |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H3B | histone cluster 1, H3b |
| HMOX1 | heme oxygenase 1 |
| HOXC6 | homeobox C6 |
| HOXC8 | homeobox C8 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL4R | interleukin 4 receptor |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KLK5 | kallikrein-related peptidase 5 |
| KRT31 | keratin 31, type I |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LPXN | leupaxin |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LYRM9 | LYR motif containing 9 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MEFV | Mediterranean fever |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MITF | microphthalmia-associated transcription factor |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPS18C | mitochondrial ribosomal protein S18C |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NLRX1 | NLR family member X1 |
| NPY5R | neuropeptide Y receptor Y5 |
| ONECUT2 | one cut homeobox 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDGFRL | platelet-derived growth factor receptor-like |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLD2 | phospholipase D2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PMEL | premelanosome protein |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PROS1 | protein S (alpha) |
| PTDSS2 | phosphatidylserine synthase 2 |
| RIN1 | Ras and Rab interactor 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| S100A2 | S100 calcium binding protein A2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SECISBP2 | SECIS binding protein 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPAG4 | sperm associated antigen 4 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TMEM121 | transmembrane protein 121 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TTBK2 | tau tubulin kinase 2 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP6NL | USP6 N-terminal like |
| VGF | VGF nerve growth factor inducible |
| WDR60 | WD repeat domain 60 |
| WDR76 | WD repeat domain 76 |
| WLS | wntless Wnt ligand secretion mediator |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF324 | zinc finger protein 324 |
| ZNF750 | zinc finger protein 750 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
