benzocaine Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component. A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant and topical anaesthetic on the larynx, mouth, nasal cavity, respiratory tract, oesophagus, rectum, urinary tract, and vagina. (Chemical Entities of Biological Interest Ontology, CHEBI_116735)
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Genes

4 genes differentially expressed following the benzocaine small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TOMM34 translocase of outer mitochondrial membrane 34 3.56773
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 3.50917

decreased expression

Symbol Name Standardized Value
ISOC1 isochorismatase domain containing 1 -3.48473
ZMYM2 zinc finger, MYM-type 2 -3.23816