benzonatate-1679 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the benzonatate-1679 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AJAP1 adherens junctions associated protein 1
AKAP10 A kinase (PRKA) anchor protein 10
ALMS1 Alstrom syndrome protein 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARF6 ADP-ribosylation factor 6
ASAP1-IT1 ASAP1 intronic transcript 1
BAG4 BCL2-associated athanogene 4
BCL2 B-cell CLL/lymphoma 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
CA5BP1 carbonic anhydrase VB pseudogene 1
CDC25C cell division cycle 25C
CDK19 cyclin-dependent kinase 19
CDON cell adhesion associated, oncogene regulated
CGREF1 cell growth regulator with EF-hand domain 1
COMMD4 COMM domain containing 4
CSRP2 cysteine and glycine-rich protein 2
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DPH5 diphthamide biosynthesis 5
FBXO31 F-box protein 31
FH fumarate hydratase
FLOT1 flotillin 1
FNDC3A fibronectin type III domain containing 3A
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPATCH4 G patch domain containing 4
GPR137 G protein-coupled receptor 137
HIPK2 homeodomain interacting protein kinase 2
HK2 hexokinase 2
ICOSLG inducible T-cell co-stimulator ligand
IL11 interleukin 11
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KIF5C kinesin family member 5C
KLF4 Kruppel-like factor 4 (gut)
LAMA4 laminin, alpha 4
LMNA lamin A/C
LONP2 lon peptidase 2, peroxisomal
LPIN1 lipin 1
LSP1 lymphocyte-specific protein 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MCOLN3 mucolipin 3
MET MET proto-oncogene, receptor tyrosine kinase
METTL5 methyltransferase like 5
METTL7A methyltransferase like 7A
MKL1 megakaryoblastic leukemia (translocation) 1
MST1 macrophage stimulating 1
MYO1F myosin IF
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NKX3-2 NK3 homeobox 2
OSBPL1A oxysterol binding protein-like 1A
PARD6B par-6 family cell polarity regulator beta
PCGF2 polycomb group ring finger 2
PHTF2 putative homeodomain transcription factor 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLK4 polo-like kinase 4
PML promyelocytic leukemia
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRR4 proline rich 4 (lacrimal)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PSD4 pleckstrin and Sec7 domain containing 4
PVT1 Pvt1 oncogene (non-protein coding)
RAB11B RAB11B, member RAS oncogene family
RAB28 RAB28, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RAD52 RAD52 homolog (S. cerevisiae)
RANBP3 RAN binding protein 3
RASAL2 RAS protein activator like 2
RBM19 RNA binding motif protein 19
RBMS2 RNA binding motif, single stranded interacting protein 2
RPL7 ribosomal protein L7
RRAGD Ras-related GTP binding D
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
SAYSD1 SAYSVFN motif domain containing 1
SCHIP1 schwannomin interacting protein 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERHL2 serine hydrolase-like 2
SETDB1 SET domain, bifurcated 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRD5A3 steroid 5 alpha-reductase 3
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STAT5B signal transducer and activator of transcription 5B
STYK1 serine/threonine/tyrosine kinase 1
SUGP1 SURP and G patch domain containing 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TMEM209 transmembrane protein 209
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM2 tripartite motif containing 2
TSPAN9 tetraspanin 9
UBOX5 U-box domain containing 5
VIPR2 vasoactive intestinal peptide receptor 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS9D1 VPS9 domain containing 1
WDFY3 WD repeat and FYVE domain containing 3
WFDC2 WAP four-disulfide core domain 2
ZBTB43 zinc finger and BTB domain containing 43
ZNF324 zinc finger protein 324
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ARRB2 arrestin, beta 2
ATG9A autophagy related 9A
BCL9 B-cell CLL/lymphoma 9
BRPF1 bromodomain and PHD finger containing, 1
C14ORF132 chromosome 14 open reading frame 132
C22ORF29 chromosome 22 open reading frame 29
CCDC9 coiled-coil domain containing 9
CDK20 cyclin-dependent kinase 20
CDT1 chromatin licensing and DNA replication factor 1
CEP97 centrosomal protein 97kDa
CHKB choline kinase beta
CIC capicua transcriptional repressor
CNN2 calponin 2
CSTA cystatin A (stefin A)
CTDNEP1 CTD nuclear envelope phosphatase 1
CXORF56 chromosome X open reading frame 56
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DCP1A decapping mRNA 1A
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EFNA3 ephrin-A3
EHD4 EH-domain containing 4
ERCC4 excision repair cross-complementation group 4
FHOD1 formin homology 2 domain containing 1
FLJ22184
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GBP2 guanylate binding protein 2, interferon-inducible
GNA12 guanine nucleotide binding protein (G protein) alpha 12
HPSE heparanase
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HYAL2 hyaluronoglucosaminidase 2
IDI2-AS1 IDI2 antisense RNA 1
IFI35 interferon-induced protein 35
IL4R interleukin 4 receptor
INPP5K inositol polyphosphate-5-phosphatase K
IP6K1 inositol hexakisphosphate kinase 1
JUNB jun B proto-oncogene
KIAA0894 KIAA0894 protein
KLHL36 kelch-like family member 36
LAMB3 laminin, beta 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRRC20 leucine rich repeat containing 20
LYPD3 LY6/PLAUR domain containing 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP1S microtubule-associated protein 1S
MAST3 microtubule associated serine/threonine kinase 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
METTL2B methyltransferase like 2B
MFAP2 microfibrillar-associated protein 2
MITF microphthalmia-associated transcription factor
MTMR12 myotubularin related protein 12
NDE1 nudE neurodevelopment protein 1
NEK11 NIMA-related kinase 11
NIPAL2 NIPA-like domain containing 2
NOD1 nucleotide-binding oligomerization domain containing 1
NPFFR1 neuropeptide FF receptor 1
NVL nuclear VCP-like
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKN1 protein kinase N1
PMCH pro-melanin-concentrating hormone
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POTEKP POTE ankyrin domain family, member K, pseudogene
PSKH1 protein serine kinase H1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTPRU protein tyrosine phosphatase, receptor type, U
QSER1 glutamine and serine rich 1
RAB33B RAB33B, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
RGS19 regulator of G-protein signaling 19
RPAP1 RNA polymerase II associated protein 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TGFB3 transforming growth factor, beta 3
THRAP3 thyroid hormone receptor associated protein 3
TMEM62 transmembrane protein 62
TPCN1 two pore segment channel 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM62 tripartite motif containing 62
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBTF upstream binding transcription factor, RNA polymerase I
UBXN6 UBX domain protein 6
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR4 WD repeat domain 4
WDR91 WD repeat domain 91
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF205 zinc finger protein 205
ZNF696 zinc finger protein 696
ZNF787 zinc finger protein 787