| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the benzonatate-1801 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACTR1B | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| ANKRD12 | ankyrin repeat domain 12 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| B9D1 | B9 protein domain 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| C6ORF120 | chromosome 6 open reading frame 120 |
| CAPN10 | calpain 10 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCNT2 | cyclin T2 |
| CES3 | carboxylesterase 3 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CREM | cAMP responsive element modulator |
| CTTN | cortactin |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ELF1 | E74-like factor 1 (ets domain transcription factor) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAS | Fas cell surface death receptor |
| FCF1 | FCF1 rRNA-processing protein |
| FH | fumarate hydratase |
| FSCN1 | fascin actin-bundling protein 1 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GLE1 | GLE1 RNA export mediator |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL22 | interleukin 22 |
| ING4 | inhibitor of growth family, member 4 |
| ITM2B | integral membrane protein 2B |
| LOC644450 | uncharacterized LOC644450 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MAX | MYC associated factor X |
| MBTD1 | mbt domain containing 1 |
| MED28 | mediator complex subunit 28 |
| MEX3D | mex-3 RNA binding family member D |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NEBL | nebulette |
| NLK | nemo-like kinase |
| NOV | nephroblastoma overexpressed |
| NPEPL1 | aminopeptidase-like 1 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
| NUP98 | nucleoporin 98kDa |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PGAP1 | post-GPI attachment to proteins 1 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PLIN2 | perilipin 2 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRKCH | protein kinase C, eta |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RBL2 | retinoblastoma-like 2 |
| RDX | radixin |
| RNF39 | ring finger protein 39 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| RSRP1 | arginine/serine-rich protein 1 |
| RUNX1 | runt-related transcription factor 1 |
| SH2B1 | SH2B adaptor protein 1 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STOM | stomatin |
| STX16 | syntaxin 16 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TBL1X | transducin (beta)-like 1X-linked |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TCF3 | transcription factor 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOR1AIP1 | torsin A interacting protein 1 |
| TSC2 | tuberous sclerosis 2 |
| WAPAL | wings apart-like homolog (Drosophila) |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZNF253 | zinc finger protein 253 |
| ZNF358 | zinc finger protein 358 |
| ZNF592 | zinc finger protein 592 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ALPK1 | alpha-kinase 1 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ATXN2 | ataxin 2 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CASZ1 | castor zinc finger 1 |
| CBX7 | chromobox homolog 7 |
| CCDC94 | coiled-coil domain containing 94 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHD3 | chromodomain helicase DNA binding protein 3 |
| CHKB | choline kinase beta |
| CHMP6 | charged multivesicular body protein 6 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNTNAP1 | contactin associated protein 1 |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| CXORF56 | chromosome X open reading frame 56 |
| DCLRE1A | DNA cross-link repair 1A |
| DMTN | dematin actin binding protein |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FAM53B | family with sequence similarity 53, member B |
| FBRS | fibrosin |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPR1 | G protein-coupled receptor 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HOMER2 | homer scaffolding protein 2 |
| HOXA1 | homeobox A1 |
| HOXC10 | homeobox C10 |
| IRF9 | interferon regulatory factor 9 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| LRRC61 | leucine rich repeat containing 61 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAGEF1 | melanoma antigen family F1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MED15 | mediator complex subunit 15 |
| METTL2B | methyltransferase like 2B |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MTMR12 | myotubularin related protein 12 |
| MXD3 | MAX dimerization protein 3 |
| NCS1 | neuronal calcium sensor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| OLFML2A | olfactomedin-like 2A |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PLD2 | phospholipase D2 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLH | polymerase (DNA directed), eta |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| POMT1 | protein-O-mannosyltransferase 1 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PUS1 | pseudouridylate synthase 1 |
| RIN1 | Ras and Rab interactor 1 |
| RNF31 | ring finger protein 31 |
| RPGR | retinitis pigmentosa GTPase regulator |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SIX1 | SIX homeobox 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SMA4 | glucuronidase, beta pseudogene |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| SNAP29 | synaptosomal-associated protein, 29kDa |
| SNX15 | sorting nexin 15 |
| SPATA2L | spermatogenesis associated 2-like |
| STX17 | syntaxin 17 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBP | TATA box binding protein |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM132A | transmembrane protein 132A |
| TMEM242 | transmembrane protein 242 |
| TOLLIP | toll interacting protein |
| TOM1 | target of myb1 (chicken) |
| TPCN1 | two pore segment channel 1 |
| TRABD | TraB domain containing |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| UBQLN4 | ubiquilin 4 |
| UBTD1 | ubiquitin domain containing 1 |
| USP19 | ubiquitin specific peptidase 19 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF32 | zinc finger protein 32 |
| ZNF574 | zinc finger protein 574 |