| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the benzonatate-1843 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ATG3 | autophagy related 3 |
| ATP11A | ATPase, class VI, type 11A |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| ATP9B | ATPase, class II, type 9B |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD47 | CD47 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CEP164 | centrosomal protein 164kDa |
| CES3 | carboxylesterase 3 |
| CFP | complement factor properdin |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CTRL | chymotrypsin-like |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DMTN | dematin actin binding protein |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DRD2 | dopamine receptor D2 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 |
| EXT2 | exostosin glycosyltransferase 2 |
| F12 | coagulation factor XII (Hageman factor) |
| FHIT | fragile histidine triad |
| GCFC2 | GC-rich sequence DNA-binding factor 2 |
| GHRHR | growth hormone releasing hormone receptor |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GRM8 | glutamate receptor, metabotropic 8 |
| HDAC7 | histone deacetylase 7 |
| HIST1H4C | histone cluster 1, H4c |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IFI44 | interferon-induced protein 44 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MAGED2 | melanoma antigen family D2 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MBP | myelin basic protein |
| METTL5 | methyltransferase like 5 |
| MIIP | migration and invasion inhibitory protein |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MTMR7 | myotubularin related protein 7 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NINJ2 | ninjurin 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHTF2 | putative homeodomain transcription factor 2 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PRDX2 | peroxiredoxin 2 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB33A | RAB33A, member RAS oncogene family |
| RBKS | ribokinase |
| RGS10 | regulator of G-protein signaling 10 |
| RPL14 | ribosomal protein L14 |
| RRBP1 | ribosome binding protein 1 |
| SBF1 | SET binding factor 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SFSWAP | splicing factor, suppressor of white-apricot family |
| SH3BP2 | SH3-domain binding protein 2 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIN3B | SIN3 transcription regulator family member B |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPIDR | scaffolding protein involved in DNA repair |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| SYNJ1 | synaptojanin 1 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TGFB3 | transforming growth factor, beta 3 |
| TMEM104 | transmembrane protein 104 |
| TMEM231 | transmembrane protein 231 |
| TRIM58 | tripartite motif containing 58 |
| TSC22D4 | TSC22 domain family, member 4 |
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| YIPF4 | Yip1 domain family, member 4 |
| ZNF236 | zinc finger protein 236 |
| ZNF254 | zinc finger protein 254 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| AHCTF1 | AT hook containing transcription factor 1 |
| AKTIP | AKT interacting protein |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| BBS10 | Bardet-Biedl syndrome 10 |
| BCL7A | B-cell CLL/lymphoma 7A |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C11ORF68 | chromosome 11 open reading frame 68 |
| CARD9 | caspase recruitment domain family, member 9 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CENPT | centromere protein T |
| CHD3 | chromodomain helicase DNA binding protein 3 |
| CISH | cytokine inducible SH2-containing protein |
| CLDN15 | claudin 15 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTSK | cathepsin K |
| CXORF56 | chromosome X open reading frame 56 |
| DBR1 | debranching RNA lariats 1 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DYM | dymeclin |
| EFHD2 | EF-hand domain family, member D2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| GPR63 | G protein-coupled receptor 63 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HIRA | histone cell cycle regulator |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| KAT2A | K(lysine) acetyltransferase 2A |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA0754 | KIAA0754 |
| KIF13B | kinesin family member 13B |
| KIF18A | kinesin family member 18A |
| LIN7A | lin-7 homolog A (C. elegans) |
| MAPK12 | mitogen-activated protein kinase 12 |
| MCMBP | minichromosome maintenance complex binding protein |
| MCRS1 | microspherule protein 1 |
| MDM4 | MDM4, p53 regulator |
| MED22 | mediator complex subunit 22 |
| MGC12488 | |
| MMP2 | matrix metallopeptidase 2 |
| MPI | mannose phosphate isomerase |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYO1E | myosin IE |
| NABP2 | nucleic acid binding protein 2 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDRG1 | N-myc downstream regulated 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NINJ1 | ninjurin 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POR | P450 (cytochrome) oxidoreductase |
| PPCS | phosphopantothenoylcysteine synthetase |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB5B | RAB5B, member RAS oncogene family |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RNF2 | ring finger protein 2 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| SETD6 | SET domain containing 6 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SHPK | sedoheptulokinase |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPI1 | Spi-1 proto-oncogene |
| STIM1 | stromal interaction molecule 1 |
| STK16 | serine/threonine kinase 16 |
| TMEM159 | transmembrane protein 159 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| WT1-AS | WT1 antisense RNA |
| XAF1 | XIAP associated factor 1 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF215 | zinc finger protein 215 |
| ZNF268 | zinc finger protein 268 |
| ZNF302 | zinc finger protein 302 |
| ZNF571 | zinc finger protein 571 |
| ZNF654 | zinc finger protein 654 |
| ZNF862 | zinc finger protein 862 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
