| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the benzonatate-6334 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ATN1 | atrophin 1 |
| BAIAP3 | BAI1-associated protein 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTG2 | BTG family, member 2 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCPG1 | cell cycle progression 1 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFAP69 | cilia and flagella associated protein 69 |
| COL11A2 | collagen, type XI, alpha 2 |
| CPNE7 | copine VII |
| DMBT1 | deleted in malignant brain tumors 1 |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| DST | dystonin |
| EMP1 | epithelial membrane protein 1 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| FLJ10038 | uncharacterized protein FLJ10038 |
| FN1 | fibronectin 1 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GPR27 | G protein-coupled receptor 27 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HNMT | histamine N-methyltransferase |
| HOXA1 | homeobox A1 |
| HOXC10 | homeobox C10 |
| IFI44L | interferon-induced protein 44-like |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNA14 | interferon, alpha 14 |
| IL6 | interleukin 6 |
| KIF1A | kinesin family member 1A |
| KLF6 | Kruppel-like factor 6 |
| KNG1 | kininogen 1 |
| LOX | lysyl oxidase |
| LY96 | lymphocyte antigen 96 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| LYRM9 | LYR motif containing 9 |
| MAK | male germ cell-associated kinase |
| MAP7 | microtubule-associated protein 7 |
| MED18 | mediator complex subunit 18 |
| MINK1 | misshapen-like kinase 1 |
| MVK | mevalonate kinase |
| NEBL | nebulette |
| NPAS2 | neuronal PAS domain protein 2 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NUP214 | nucleoporin 214kDa |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PENK | proenkephalin |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLK3 | polo-like kinase 3 |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRF1 | perforin 1 (pore forming protein) |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RIF1 | replication timing regulatory factor 1 |
| RPS3A | ribosomal protein S3A |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SRRT | serrate, RNA effector molecule |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYMPK | symplekin |
| SYNGR3 | synaptogyrin 3 |
| SYNJ2 | synaptojanin 2 |
| TGFB2 | transforming growth factor, beta 2 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THBD | thrombomodulin |
| TMEM63A | transmembrane protein 63A |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRAF2 | TNF receptor-associated factor 2 |
| UBXN1 | UBX domain protein 1 |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| UTS2 | urotensin 2 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| WDR1 | WD repeat domain 1 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF140 | zinc finger protein 140 |
| ZNF446 | zinc finger protein 446 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ALS2CL | ALS2 C-terminal like |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASL | argininosuccinate lyase |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C16ORF62 | chromosome 16 open reading frame 62 |
| C1R | complement component 1, r subcomponent |
| CCDC106 | coiled-coil domain containing 106 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDKN2AIP | CDKN2A interacting protein |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHMP1A | charged multivesicular body protein 1A |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CNTNAP1 | contactin associated protein 1 |
| COG4 | component of oligomeric golgi complex 4 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CRYL1 | crystallin, lambda 1 |
| CTAGE9 | CTAGE family, member 9 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| EPPK1 | epiplakin 1 |
| ERF | Ets2 repressor factor |
| FAIM | Fas apoptotic inhibitory molecule |
| FEM1C | fem-1 homolog c (C. elegans) |
| FOXC1 | forkhead box C1 |
| FUZ | fuzzy planar cell polarity protein |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPS1 | G protein pathway suppressor 1 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIRA | histone cell cycle regulator |
| HLX | H2.0-like homeobox |
| HMOX1 | heme oxygenase 1 |
| HOXB9 | homeobox B9 |
| IL17RA | interleukin 17 receptor A |
| IL4R | interleukin 4 receptor |
| IREB2 | iron-responsive element binding protein 2 |
| IRF9 | interferon regulatory factor 9 |
| KIF13B | kinesin family member 13B |
| LMNB1 | lamin B1 |
| LOC730101 | uncharacterized LOC730101 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MCRS1 | microspherule protein 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MOB3B | MOB kinase activator 3B |
| MOSPD3 | motile sperm domain containing 3 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MPST | mercaptopyruvate sulfurtransferase |
| NECAP2 | NECAP endocytosis associated 2 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NID2 | nidogen 2 (osteonidogen) |
| NPR3 | natriuretic peptide receptor 3 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLSCR4 | phospholipid scramblase 4 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB5B | RAB5B, member RAS oncogene family |
| REEP4 | receptor accessory protein 4 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SALL2 | spalt-like transcription factor 2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SPEG | SPEG complex locus |
| ST5 | suppression of tumorigenicity 5 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TAGLN3 | transgelin 3 |
| TESK2 | testis-specific kinase 2 |
| THBS3 | thrombospondin 3 |
| TMC5 | transmembrane channel-like 5 |
| TMEM134 | transmembrane protein 134 |
| TMEM209 | transmembrane protein 209 |
| TMEM8B | transmembrane protein 8B |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TSPAN15 | tetraspanin 15 |
| TUBA3C | tubulin, alpha 3c |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| YIPF1 | Yip1 domain family, member 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF112 | zinc finger protein 112 |
| ZNF134 | zinc finger protein 134 |
| ZNF253 | zinc finger protein 253 |
| ZNF254 | zinc finger protein 254 |
| ZNF408 | zinc finger protein 408 |
| ZNF574 | zinc finger protein 574 |
| ZNF862 | zinc finger protein 862 |
| ZXDC | ZXD family zinc finger C |