benzthiazide-3329 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the benzthiazide-3329 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AMH anti-Mullerian hormone
AMPD3 adenosine monophosphate deaminase 3
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARID1A AT rich interactive domain 1A (SWI-like)
ARR3 arrestin 3, retinal (X-arrestin)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
AUTS2 autism susceptibility candidate 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C21ORF2 chromosome 21 open reading frame 2
C3ORF18 chromosome 3 open reading frame 18
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CD1A CD1a molecule
CD47 CD47 molecule
CDC14B cell division cycle 14B
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDK6 cyclin-dependent kinase 6
CDRT1 CMT1A duplicated region transcript 1
CFHR4 complement factor H-related 4
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CNTN5 contactin 5
COL11A2 collagen, type XI, alpha 2
CTIF CBP80/20-dependent translation initiation factor
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DKFZP434L187 uncharacterized LOC26082
DNASE1 deoxyribonuclease I
DOK4 docking protein 4
DUSP10 dual specificity phosphatase 10
ELP6 elongator acetyltransferase complex subunit 6
ERCC2 excision repair cross-complementation group 2
FKRP fukutin related protein
FLT3LG fms-related tyrosine kinase 3 ligand
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GIF gastric intrinsic factor (vitamin B synthesis)
GJA4 gap junction protein, alpha 4, 37kDa
GPR161 G protein-coupled receptor 161
GPR3 G protein-coupled receptor 3
GRPR gastrin-releasing peptide receptor
HEG1 heart development protein with EGF-like domains 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HLA-DOA major histocompatibility complex, class II, DO alpha
HLF hepatic leukemia factor
ICOSLG inducible T-cell co-stimulator ligand
IDI2-AS1 IDI2 antisense RNA 1
IGFBP3 insulin-like growth factor binding protein 3
IL2RG interleukin 2 receptor, gamma
IL6R interleukin 6 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM4B lysine (K)-specific demethylase 4B
KDM8 lysine (K)-specific demethylase 8
LAG3 lymphocyte-activation gene 3
LEPR leptin receptor
LOC644450 uncharacterized LOC644450
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MBD2 methyl-CpG binding domain protein 2
MED16 mediator complex subunit 16
MEF2C myocyte enhancer factor 2C
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MNMIP1 manchette microtubule inner protein 1
MPL MPL proto-oncogene, thrombopoietin receptor
N4BP2L1 NEDD4 binding protein 2-like 1
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NEUROD4 neuronal differentiation 4
NME5 NME/NM23 family member 5
NPHP1 nephronophthisis 1 (juvenile)
NPR3 natriuretic peptide receptor 3
OLFML2A olfactomedin-like 2A
ONECUT2 one cut homeobox 2
PAX2 paired box 2
PCDHGA8 protocadherin gamma subfamily A, 8
PDE4D phosphodiesterase 4D, cAMP-specific
PIPOX pipecolic acid oxidase
PML promyelocytic leukemia
PODNL1 podocan-like 1
POMT2 protein-O-mannosyltransferase 2
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
RIMS2 regulating synaptic membrane exocytosis 2
RUNX1 runt-related transcription factor 1
SAFB2 scaffold attachment factor B2
SH3BP2 SH3-domain binding protein 2
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC43A3 solute carrier family 43, member 3
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SUGP1 SURP and G patch domain containing 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIMP3 TIMP metallopeptidase inhibitor 3
TMPRSS15 transmembrane protease, serine 15
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
ZNF280A zinc finger protein 280A
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABLIM3 actin binding LIM protein family, member 3
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTN4 actinin, alpha 4
ADAM15 ADAM metallopeptidase domain 15
ADAP2 ArfGAP with dual PH domains 2
AFAP1 actin filament associated protein 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B9D2 B9 protein domain 2
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCNK cyclin K
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDK20 cyclin-dependent kinase 20
CGA glycoprotein hormones, alpha polypeptide
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CRELD1 cysteine-rich with EGF-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCLRE1A DNA cross-link repair 1A
DDA1 DET1 and DDB1 associated 1
DDIT3 DNA-damage-inducible transcript 3
DIXDC1 DIX domain containing 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
ENO3 enolase 3 (beta, muscle)
EVA1B eva-1 homolog B (C. elegans)
EXOC5 exocyst complex component 5
FBRS fibrosin
FER fer (fps/fes related) tyrosine kinase
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP5 FK506 binding protein 5
GBP2 guanylate binding protein 2, interferon-inducible
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HDAC7 histone deacetylase 7
HIST1H2AL histone cluster 1, H2al
HLA-J major histocompatibility complex, class I, J (pseudogene)
HPN hepsin
IRF1 interferon regulatory factor 1
KIAA0319L KIAA0319-like
LHX1 LIM homeobox 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MMP2 matrix metallopeptidase 2
MTRF1 mitochondrial translational release factor 1
MVP major vault protein
MYOZ3 myozenin 3
NIPAL2 NIPA-like domain containing 2
NPIPB3 nuclear pore complex interacting protein family, member B3
NPM3 nucleophosmin/nucleoplasmin 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSGIN1 oxidative stress induced growth inhibitor 1
OSMR oncostatin M receptor
PC pyruvate carboxylase
PCDHA6 protocadherin alpha 6
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POM121 POM121 transmembrane nucleoporin
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3D RAB3D, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REPS2 RALBP1 associated Eps domain containing 2
RNF123 ring finger protein 123
RNF126P1 ring finger protein 126 pseudogene 1
S100A9 S100 calcium binding protein A9
SDC3 syndecan 3
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC16A6 solute carrier family 16, member 6
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC41A3 solute carrier family 41, member 3
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD3 StAR-related lipid transfer (START) domain containing 3
SYBU syntabulin (syntaxin-interacting)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D17 TBC1 domain family, member 17
TCTN1 tectonic family member 1
THRB thyroid hormone receptor, beta
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN1 tetraspanin 1
UBE2L6 ubiquitin-conjugating enzyme E2L 6
USP27X ubiquitin specific peptidase 27, X-linked
WDR25 WD repeat domain 25
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene
ZNF37BP zinc finger protein 37B, pseudogene
ZNF480 zinc finger protein 480
ZNF747 zinc finger protein 747