benzydamine-1552 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the benzydamine-1552 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACAA2 acetyl-CoA acyltransferase 2
ACAN aggrecan
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADM2 adrenomedullin 2
AFF2 AF4/FMR2 family, member 2
ANKRD55 ankyrin repeat domain 55
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ASMTL acetylserotonin O-methyltransferase-like
ATP5SL ATP5S-like
BRIX1 BRX1, biogenesis of ribosomes
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCDC85B coiled-coil domain containing 85B
CCNT1 cyclin T1
CCPG1 cell cycle progression 1
CLEC4E C-type lectin domain family 4, member E
CPOX coproporphyrinogen oxidase
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTBP2 C-terminal binding protein 2
DBF4 DBF4 zinc finger
DEAF1 DEAF1 transcription factor
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DPF3 D4, zinc and double PHD fingers, family 3
DUSP13 dual specificity phosphatase 13
EFCAB14 EF-hand calcium binding domain 14
EIF3M eukaryotic translation initiation factor 3, subunit M
ELK1 ELK1, member of ETS oncogene family
EPOR erythropoietin receptor
FANCF Fanconi anemia, complementation group F
FAXDC2 fatty acid hydroxylase domain containing 2
FH fumarate hydratase
FKBP9 FK506 binding protein 9, 63 kDa
GEMIN6 gem (nuclear organelle) associated protein 6
GJD2 gap junction protein, delta 2, 36kDa
GLT8D1 glycosyltransferase 8 domain containing 1
GMEB1 glucocorticoid modulatory element binding protein 1
GRK5 G protein-coupled receptor kinase 5
GSS glutathione synthetase
HDAC5 histone deacetylase 5
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HRH1 histamine receptor H1
IGF1R insulin-like growth factor 1 receptor
IL13 interleukin 13
IL1RN interleukin 1 receptor antagonist
ITGA10 integrin, alpha 10
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KTN1 kinectin 1 (kinesin receptor)
LAD1 ladinin 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
METTL8 methyltransferase like 8
MIEF1 mitochondrial elongation factor 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP19 matrix metallopeptidase 19
MRPS12 mitochondrial ribosomal protein S12
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
N4BP1 NEDD4 binding protein 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDRG2 NDRG family member 2
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NPTXR neuronal pentraxin receptor
NRGN neurogranin (protein kinase C substrate, RC3)
OR10H3 olfactory receptor, family 10, subfamily H, member 3
PCIF1 PDX1 C-terminal inhibiting factor 1
PDS5A PDS5 cohesin associated factor A
PLCB4 phospholipase C, beta 4
PLCD1 phospholipase C, delta 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPT2 palmitoyl-protein thioesterase 2
RAB20 RAB20, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RANBP3 RAN binding protein 3
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL10 ribosomal protein L10
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RRP1B ribosomal RNA processing 1B
SAMM50 SAMM50 sorting and assembly machinery component
SCARB2 scavenger receptor class B, member 2
SDHAF3 succinate dehydrogenase complex assembly factor 3
SEC23B Sec23 homolog B (S. cerevisiae)
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SFSWAP splicing factor, suppressor of white-apricot family
SH3BP2 SH3-domain binding protein 2
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC17A4 solute carrier family 17, member 4
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTB spectrin, beta, erythrocytic
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
TERF2 telomeric repeat binding factor 2
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TM2D1 TM2 domain containing 1
TMEM164 transmembrane protein 164
USF2 upstream transcription factor 2, c-fos interacting
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WIZ widely interspaced zinc finger motifs
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOBR apolipoprotein B receptor
ARL4A ADP-ribosylation factor-like 4A
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD2B ATPase family, AAA domain containing 2B
ATG2A autophagy related 2A
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
C11ORF68 chromosome 11 open reading frame 68
C11ORF95 chromosome 11 open reading frame 95
C17ORF70 chromosome 17 open reading frame 70
C4ORF29 chromosome 4 open reading frame 29
C9ORF114 chromosome 9 open reading frame 114
CAPG capping protein (actin filament), gelsolin-like
CCDC176 coiled-coil domain containing 176
CEP170B centrosomal protein 170B
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLDN15 claudin 15
CLTCL1 clathrin, heavy chain-like 1
CMTR1 cap methyltransferase 1
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COG7 component of oligomeric golgi complex 7
DCAF16 DDB1 and CUL4 associated factor 16
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DOK2 docking protein 2, 56kDa
EFTUD1 elongation factor Tu GTP binding domain containing 1
EMD emerin
EXOSC10 exosome component 10
FAM50A family with sequence similarity 50, member A
FBXL6 F-box and leucine-rich repeat protein 6
FBXO46 F-box protein 46
GBP2 guanylate binding protein 2, interferon-inducible
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
HAUS2 HAUS augmin-like complex, subunit 2
HLTF helicase-like transcription factor
HRAS Harvey rat sarcoma viral oncogene homolog
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFITM3 interferon induced transmembrane protein 3
IGKV1D-13 immunoglobulin kappa variable 1D-13
IRAK4 interleukin-1 receptor-associated kinase 4
KIF3B kinesin family member 3B
LIAS lipoic acid synthetase
LIMA1 LIM domain and actin binding 1
LIN37 lin-37 DREAM MuvB core complex component
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MGA MGA, MAX dimerization protein
MYBBP1A MYB binding protein (P160) 1a
MYO19 myosin XIX
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NEFH neurofilament, heavy polypeptide
NHEJ1 nonhomologous end-joining factor 1
NSD1 nuclear receptor binding SET domain protein 1
NUP93 nucleoporin 93kDa
NXF1 nuclear RNA export factor 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PCTP phosphatidylcholine transfer protein
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
POLE polymerase (DNA directed), epsilon, catalytic subunit
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRPF3 pre-mRNA processing factor 3
PSKH1 protein serine kinase H1
QRICH1 glutamine-rich 1
RAD9A RAD9 homolog A (S. pombe)
RBM4B RNA binding motif protein 4B
RBMS3 RNA binding motif, single stranded interacting protein 3
RNF146 ring finger protein 146
RPP38 ribonuclease P/MRP 38kDa subunit
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RWDD2B RWD domain containing 2B
SF3B2 splicing factor 3b, subunit 2, 145kDa
SLC22A18 solute carrier family 22, member 18
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAC3 tachykinin 3
TIPIN TIMELESS interacting protein
TJP2 tight junction protein 2
TMEM11 transmembrane protein 11
TMEM53 transmembrane protein 53
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TSPAN32 tetraspanin 32
TUBA4B tubulin, alpha 4b
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
URGCP upregulator of cell proliferation
URM1 ubiquitin related modifier 1
VWA9 von Willebrand factor A domain containing 9
ZNF175 zinc finger protein 175
ZNF212 zinc finger protein 212
ZNF264 zinc finger protein 264
ZNF33B zinc finger protein 33B
ZNF394 zinc finger protein 394
ZNF426 zinc finger protein 426
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF839 zinc finger protein 839