benzydamine-3169 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the benzydamine-3169 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ACVR1B activin A receptor, type IB
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARPIN actin-related protein 2/3 complex inhibitor
ATN1 atrophin 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BEGAIN brain-enriched guanylate kinase-associated
CALCR calcitonin receptor
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CARD9 caspase recruitment domain family, member 9
CD40 CD40 molecule, TNF receptor superfamily member 5
CD47 CD47 molecule
CDC14A cell division cycle 14A
CDK18 cyclin-dependent kinase 18
CEP164 centrosomal protein 164kDa
CFAP70 cilia and flagella associated protein 70
CHN2 chimerin 2
COL10A1 collagen, type X, alpha 1
COL6A2 collagen, type VI, alpha 2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CXCR3 chemokine (C-X-C motif) receptor 3
DOCK4 dedicator of cytokinesis 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNB3 ephrin-B3
EXOC7 exocyst complex component 7
FAM110D family with sequence similarity 110, member D
FOXN3 forkhead box N3
FSCN3 fascin actin-bundling protein 3, testicular
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GDF10 growth differentiation factor 10
HFE hemochromatosis
HIST1H4H histone cluster 1, H4h
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNF4A hepatocyte nuclear factor 4, alpha
JAK2 Janus kinase 2
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIF17 kinesin family member 17
KMT2A lysine (K)-specific methyltransferase 2A
LEFTY1 left-right determination factor 1
LIF leukemia inhibitory factor
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK10 mitogen-activated protein kinase 10
MMP3 matrix metallopeptidase 3
MUC3B mucin 3B, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NOL10 nucleolar protein 10
NR0B2 nuclear receptor subfamily 0, group B, member 2
OR7A17 olfactory receptor, family 7, subfamily A, member 17
OSBPL3 oxysterol binding protein-like 3
PCDHB12 protocadherin beta 12
PCOLCE procollagen C-endopeptidase enhancer
PCSK6 proprotein convertase subtilisin/kexin type 6
PECAM1 platelet/endothelial cell adhesion molecule 1
PLXNB2 plexin B2
PLXNC1 plexin C1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PQLC3 PQ loop repeat containing 3
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
RBBP9 retinoblastoma binding protein 9
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGCC regulator of cell cycle
RND1 Rho family GTPase 1
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPL10 ribosomal protein L10
SELL selectin L
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMR3A submaxillary gland androgen regulated protein 3A
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPAG8 sperm associated antigen 8
SPRED2 sprouty-related, EVH1 domain containing 2
STOML1 stomatin (EPB72)-like 1
SYNC syncoilin, intermediate filament protein
TAS2R10 taste receptor, type 2, member 10
TAT tyrosine aminotransferase
TBL1Y transducin (beta)-like 1, Y-linked
TBX21 T-box 21
TDRKH tudor and KH domain containing
TEK TEK tyrosine kinase, endothelial
TEP1 telomerase-associated protein 1
TGFB2 transforming growth factor, beta 2
THAP9 THAP domain containing 9
TMCC2 transmembrane and coiled-coil domain family 2
TNK2 tyrosine kinase, non-receptor, 2
TPP1 tripeptidyl peptidase I
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TWISTNB TWIST neighbor
UGT8 UDP glycosyltransferase 8
VDAC3 voltage-dependent anion channel 3
WDR4 WD repeat domain 4
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF197 zinc finger protein 197
ZNF345 zinc finger protein 345
ZNF45 zinc finger protein 45
ZNF506 zinc finger protein 506
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADAM15 ADAM metallopeptidase domain 15
ADGRE5 adhesion G protein-coupled receptor E5
AFAP1 actin filament associated protein 1
AFF4 AF4/FMR2 family, member 4
AKAP12 A kinase (PRKA) anchor protein 12
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMC7 armadillo repeat containing 7
ASAP1-IT1 ASAP1 intronic transcript 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C11ORF30 chromosome 11 open reading frame 30
C11ORF80 chromosome 11 open reading frame 80
C14ORF93 chromosome 14 open reading frame 93
C2ORF27A chromosome 2 open reading frame 27A
CAMKV CaM kinase-like vesicle-associated
CAPN15 calpain 15
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD53 CD53 molecule
CD82 CD82 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRY2 cryptochrome circadian clock 2
DCAF13 DDB1 and CUL4 associated factor 13
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DEAF1 DEAF1 transcription factor
DSCAM Down syndrome cell adhesion molecule
EAF2 ELL associated factor 2
FANCE Fanconi anemia, complementation group E
FLJ11710 uncharacterized protein FLJ11710
FRS2 fibroblast growth factor receptor substrate 2
GMPR guanosine monophosphate reductase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRB7 growth factor receptor-bound protein 7
HIST1H2AE histone cluster 1, H2ae
HLA-J major histocompatibility complex, class I, J (pseudogene)
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC5 homeobox C5
IFT22 intraflagellar transport 22
IL15RA interleukin 15 receptor, alpha
IL17RA interleukin 17 receptor A
JUNB jun B proto-oncogene
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD20 potassium channel tetramerization domain containing 20
KREMEN2 kringle containing transmembrane protein 2
KRT83 keratin 83, type II
LDHB lactate dehydrogenase B
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMO2 LIM domain only 2 (rhombotin-like 1)
LRRC37A3 leucine rich repeat containing 37, member A3
LYZ lysozyme
MFAP2 microfibrillar-associated protein 2
MPO myeloperoxidase
MXD3 MAX dimerization protein 3
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NHEJ1 nonhomologous end-joining factor 1
NPM3 nucleophosmin/nucleoplasmin 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PC pyruvate carboxylase
PCBP4 poly(rC) binding protein 4
PCSK7 proprotein convertase subtilisin/kexin type 7
PGPEP1 pyroglutamyl-peptidase I
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNA3 plexin A3
PMP22 peripheral myelin protein 22
PRR4 proline rich 4 (lacrimal)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFTN1 raftlin, lipid raft linker 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH2D4A SH2 domain containing 4A
SIRT6 sirtuin 6
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SOX12 SRY (sex determining region Y)-box 12
SPINK4 serine peptidase inhibitor, Kazal type 4
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SRD5A3 steroid 5 alpha-reductase 3
SRGN serglycin
STK16 serine/threonine kinase 16
STON1 stonin 1
STX1A syntaxin 1A (brain)
TCP10 t-complex 10
TIGD6 tigger transposable element derived 6
TMEM180 transmembrane protein 180
TOLLIP toll interacting protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR25 WD repeat domain 25
ZMAT5 zinc finger, matrin-type 5
ZNF227 zinc finger protein 227
ZNF324 zinc finger protein 324
ZNF442 zinc finger protein 442
ZNF446 zinc finger protein 446
ZNF701 zinc finger protein 701
ZNF816 zinc finger protein 816