benzydamine-7169 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the benzydamine-7169 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK2 adenylate kinase 2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARFRP1 ADP-ribosylation factor related protein 1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BCAM basal cell adhesion molecule (Lutheran blood group)
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BTF3P11 basic transcription factor 3 pseudogene 11
CADM3 cell adhesion molecule 3
CAMKMT calmodulin-lysine N-methyltransferase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCNG2 cyclin G2
CD7 CD7 molecule
CDKL3 cyclin-dependent kinase-like 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CIDEB cell death-inducing DFFA-like effector b
COL6A1 collagen, type VI, alpha 1
CTNS cystinosin, lysosomal cystine transporter
CUL2 cullin 2
DCTN1 dynactin 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DOK4 docking protein 4
DTNA dystrobrevin, alpha
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FHL1 four and a half LIM domains 1
FILIP1L filamin A interacting protein 1-like
FLRT3 fibronectin leucine rich transmembrane protein 3
FLT4 fms-related tyrosine kinase 4
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HAPLN1 hyaluronan and proteoglycan link protein 1
ICAM1 intercellular adhesion molecule 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IFT140 intraflagellar transport 140
IFT22 intraflagellar transport 22
IGFBP3 insulin-like growth factor binding protein 3
IGLJ3 immunoglobulin lambda joining 3
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
KIAA0141 KIAA0141
KLF3 Kruppel-like factor 3 (basic)
KRIT1 KRIT1, ankyrin repeat containing
LIF leukemia inhibitory factor
LMO2 LIM domain only 2 (rhombotin-like 1)
LONP2 lon peptidase 2, peroxisomal
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBD3 methyl-CpG binding domain protein 3
MBNL2 muscleblind-like splicing regulator 2
MPPED2 metallophosphoesterase domain containing 2
MVK mevalonate kinase
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDCD2 programmed cell death 2
PDE12 phosphodiesterase 12
PDE4DIP phosphodiesterase 4D interacting protein
PIBF1 progesterone immunomodulatory binding factor 1
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRPH peripherin
RABGAP1L RAB GTPase activating protein 1-like
RCAN1 regulator of calcineurin 1
RER1 retention in endoplasmic reticulum sorting receptor 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RHOQ ras homolog family member Q
RPL10 ribosomal protein L10
RPLP2 ribosomal protein, large, P2
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SAMD9 sterile alpha motif domain containing 9
SCAI suppressor of cancer cell invasion
SCAPER S-phase cyclin A-associated protein in the ER
SGK2 serum/glucocorticoid regulated kinase 2
SH3BP2 SH3-domain binding protein 2
SKIL SKI-like proto-oncogene
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC35F5 solute carrier family 35, member F5
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMR3A submaxillary gland androgen regulated protein 3A
SOCS5 suppressor of cytokine signaling 5
SSPN sarcospan
SSX1 synovial sarcoma, X breakpoint 1
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TLE4 transducin-like enhancer of split 4
TMEM2 transmembrane protein 2
TMPRSS2 transmembrane protease, serine 2
TRAF3 TNF receptor-associated factor 3
UBXN1 UBX domain protein 1
VAMP5 vesicle-associated membrane protein 5
VARS valyl-tRNA synthetase
YY2 YY2 transcription factor
ZNF211 zinc finger protein 211
ZNF350 zinc finger protein 350
ZNF440 zinc finger protein 440
ZSCAN31 zinc finger and SCAN domain containing 31

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAM15 ADAM metallopeptidase domain 15
ALPK1 alpha-kinase 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C22ORF29 chromosome 22 open reading frame 29
CCDC85C coiled-coil domain containing 85C
CCDC88C coiled-coil domain containing 88C
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COCH cochlin
COL4A5 collagen, type IV, alpha 5
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNA2 DNA replication helicase/nuclease 2
DUSP8 dual specificity phosphatase 8
EAF2 ELL associated factor 2
EVPL envoplakin
FAM114A2 family with sequence similarity 114, member A2
FAM192A family with sequence similarity 192, member A
FAM53B family with sequence similarity 53, member B
FKBP10 FK506 binding protein 10, 65 kDa
FKBP14 FK506 binding protein 14, 22 kDa
GAN gigaxonin
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IL15RA interleukin 15 receptor, alpha
IRF2BP1 interferon regulatory factor 2 binding protein 1
JUNB jun B proto-oncogene
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0319L KIAA0319-like
KREMEN2 kringle containing transmembrane protein 2
LOXL1 lysyl oxidase-like 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAPKBP1 mitogen-activated protein kinase binding protein 1
MOCS3 molybdenum cofactor synthesis 3
MT1HL1 metallothionein 1H-like 1
MUM1 melanoma associated antigen (mutated) 1
NBEAL2 neurobeachin-like 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
OLFML3 olfactomedin-like 3
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PCSK7 proprotein convertase subtilisin/kexin type 7
PELI1 pellino E3 ubiquitin protein ligase 1
PEX26 peroxisomal biogenesis factor 26
PHACTR4 phosphatase and actin regulator 4
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLA2G15 phospholipase A2, group XV
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMM2 phosphomannomutase 2
PODXL podocalyxin-like
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PYGB phosphorylase, glycogen; brain
RAD54L RAD54-like (S. cerevisiae)
RBL1 retinoblastoma-like 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF123 ring finger protein 123
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SCN1B sodium channel, voltage gated, type I beta subunit
SH2D4A SH2 domain containing 4A
SIK1 salt-inducible kinase 1
SLC12A8 solute carrier family 12, member 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMYD5 SMYD family member 5
SOBP sine oculis binding protein homolog (Drosophila)
SPAG7 sperm associated antigen 7
STARD13 StAR-related lipid transfer (START) domain containing 13
SUSD4 sushi domain containing 4
TBX19 T-box 19
THBS3 thrombospondin 3
THRAP3 thyroid hormone receptor associated protein 3
TLR5 toll-like receptor 5
TMEM104 transmembrane protein 104
TRABD TraB domain containing
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSKU tsukushi, small leucine rich proteoglycan
TTC23 tetratricopeptide repeat domain 23
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
URGCP upregulator of cell proliferation
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZBTB6 zinc finger and BTB domain containing 6
ZC3H3 zinc finger CCCH-type containing 3
ZNF552 zinc finger protein 552
ZNF701 zinc finger protein 701