benzylpenicillin-3577 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the benzylpenicillin-3577 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ADAMTSL4 ADAMTS-like 4
ADCK2 aarF domain containing kinase 2
ADGRF1 adhesion G protein-coupled receptor F1
ADGRF5 adhesion G protein-coupled receptor F5
AIM1L absent in melanoma 1-like
AIM2 absent in melanoma 2
ASIC3 acid sensing (proton gated) ion channel 3
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C21ORF2 chromosome 21 open reading frame 2
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACTIN cactin, spliceosome C complex subunit
CCDC87 coiled-coil domain containing 87
CD79B CD79b molecule, immunoglobulin-associated beta
CDK13 cyclin-dependent kinase 13
CLCA3P chloride channel accessory 3, pseudogene
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CPQ carboxypeptidase Q
CXORF21 chromosome X open reading frame 21
DBP D site of albumin promoter (albumin D-box) binding protein
DBT dihydrolipoamide branched chain transacylase E2
DRD2 dopamine receptor D2
EFR3B EFR3 homolog B (S. cerevisiae)
EPX eosinophil peroxidase
FADS3 fatty acid desaturase 3
FAM212B family with sequence similarity 212, member B
FGFR1 fibroblast growth factor receptor 1
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FSCN3 fascin actin-bundling protein 3, testicular
GIPR gastric inhibitory polypeptide receptor
GOLGA8A golgin A8 family, member A
GPR27 G protein-coupled receptor 27
GRM1 glutamate receptor, metabotropic 1
HDAC7 histone deacetylase 7
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXB5 homeobox B5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGLL1 immunoglobulin lambda-like polypeptide 1
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KL klotho
LHB luteinizing hormone beta polypeptide
LINC00341 long intergenic non-protein coding RNA 341
LMO1 LIM domain only 1 (rhombotin 1)
LRRN3 leucine rich repeat neuronal 3
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MATN1 matrilin 1, cartilage matrix protein
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MCAM melanoma cell adhesion molecule
MCM3AP minichromosome maintenance complex component 3 associated protein
MRC2 mannose receptor, C type 2
MTA1 metastasis associated 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYOF myoferlin
MYOZ1 myozenin 1
NAG18 NAG18 mRNA
NRG1 neuregulin 1
NTM neurotrimin
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OASL 2'-5'-oligoadenylate synthetase-like
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDLIM4 PDZ and LIM domain 4
PEX5L peroxisomal biogenesis factor 5-like
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PROX1 prospero homeobox 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
QPCT glutaminyl-peptide cyclotransferase
RAP2B RAP2B, member of RAS oncogene family
RBM5 RNA binding motif protein 5
RFXAP regulatory factor X-associated protein
RGS12 regulator of G-protein signaling 12
RND1 Rho family GTPase 1
RNF122 ring finger protein 122
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A9 S100 calcium binding protein A9
SAG S-antigen; retina and pineal gland (arrestin)
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SH3BP2 SH3-domain binding protein 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
TACR2 tachykinin receptor 2
TAS2R10 taste receptor, type 2, member 10
TCP11L1 t-complex 11, testis-specific-like 1
THY1 Thy-1 cell surface antigen
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TSHR thyroid stimulating hormone receptor
UROD uroporphyrinogen decarboxylase
VIPR2 vasoactive intestinal peptide receptor 2
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
VPS9D1 VPS9 domain containing 1
WSCD1 WSC domain containing 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACSF2 acyl-CoA synthetase family member 2
ADGRE5 adhesion G protein-coupled receptor E5
ANKRD36 ankyrin repeat domain 36
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP10D ATPase, class V, type 10D
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
C19ORF73 chromosome 19 open reading frame 73
CCNL2 cyclin L2
CCP110 centriolar coiled coil protein 110kDa
CDK3 cyclin-dependent kinase 3
CHRM3 cholinergic receptor, muscarinic 3
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIC capicua transcriptional repressor
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORO2A coronin, actin binding protein, 2A
CSTA cystatin A (stefin A)
DEAF1 DEAF1 transcription factor
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
F2R coagulation factor II (thrombin) receptor
FAM184A family with sequence similarity 184, member A
FBRS fibrosin
FKBP5 FK506 binding protein 5
FLJ11710 uncharacterized protein FLJ11710
FOSL1 FOS-like antigen 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GMIP GEM interacting protein
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR176 G protein-coupled receptor 176
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2BC histone cluster 1, H2bc
HIST1H4D histone cluster 1, H4d
HOXC10 homeobox C10
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
HYI hydroxypyruvate isomerase (putative)
IL17RA interleukin 17 receptor A
IRF6 interferon regulatory factor 6
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LAMA5 laminin, alpha 5
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAGEA6 melanoma antigen family A6
MAN2C1 mannosidase, alpha, class 2C, member 1
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEFV Mediterranean fever
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP2 matrix metallopeptidase 2
MRPS18C mitochondrial ribosomal protein S18C
MXD3 MAX dimerization protein 3
NCALD neurocalcin delta
NDE1 nudE neurodevelopment protein 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
PCDHB3 protocadherin beta 3
PER3 period circadian clock 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PNPLA6 patatin-like phospholipase domain containing 6
QTRT1 queuine tRNA-ribosyltransferase 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RNF31 ring finger protein 31
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RUNDC3B RUN domain containing 3B
SCAI suppressor of cancer cell invasion
SCARB1 scavenger receptor class B, member 1
SCRN3 secernin 3
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERGEF secretion regulating guanine nucleotide exchange factor
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLMO1 slowmo homolog 1 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX3 SRY (sex determining region Y)-box 3
STXBP2 syntaxin binding protein 2
SULT4A1 sulfotransferase family 4A, member 1
SYCP2 synaptonemal complex protein 2
TAGLN transgelin
TDRD1 tudor domain containing 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLR5 toll-like receptor 5
TMUB2 transmembrane and ubiquitin-like domain containing 2
TPCN1 two pore segment channel 1
TTC33 tetratricopeptide repeat domain 33
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
VASH1 vasohibin 1
VEZT vezatin, adherens junctions transmembrane protein
VGF VGF nerve growth factor inducible
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZNF286A zinc finger protein 286A
ZNF480 zinc finger protein 480
ZNF696 zinc finger protein 696
ZNF701 zinc finger protein 701
ZNF767P zinc finger family member 767, pseudogene