benzylpenicillin-4501 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the benzylpenicillin-4501 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
AMPD3 adenosine monophosphate deaminase 3
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARSD arylsulfatase D
ATF7IP activating transcription factor 7 interacting protein
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BMP10 bone morphogenetic protein 10
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA5B carbonic anhydrase VB, mitochondrial
CALHM2 calcium homeostasis modulator 2
CARF calcium responsive transcription factor
CNR2 cannabinoid receptor 2 (macrophage)
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL16A1 collagen, type XVI, alpha 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSF1 colony stimulating factor 1 (macrophage)
CSHL1 chorionic somatomammotropin hormone-like 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCTN1 dynactin 1
DIO2 deiodinase, iodothyronine, type II
DLX4 distal-less homeobox 4
DSTYK dual serine/threonine and tyrosine protein kinase
ECE1 endothelin converting enzyme 1
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EPHA4 EPH receptor A4
ERC1 ELKS/RAB6-interacting/CAST family member 1
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FHIT fragile histidine triad
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GADD45B growth arrest and DNA-damage-inducible, beta
GAP43 growth associated protein 43
GGT1 gamma-glutamyltransferase 1
GLE1 GLE1 RNA export mediator
GPATCH4 G patch domain containing 4
GZMK granzyme K (granzyme 3; tryptase II)
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AK histone cluster 1, H2ak
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD14 potassium channel tetramerization domain containing 14
KIAA1467 KIAA1467
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KITLG KIT ligand
KLHL4 kelch-like family member 4
KRTAP1-1 keratin associated protein 1-1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LY9 lymphocyte antigen 9
MAN2A2 mannosidase, alpha, class 2A, member 2
MIER2 mesoderm induction early response 1, family member 2
MMP3 matrix metallopeptidase 3
MORC1 MORC family CW-type zinc finger 1
MR1 major histocompatibility complex, class I-related
MYOZ1 myozenin 1
NCALD neurocalcin delta
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAOX polyamine oxidase (exo-N4-amino)
PAPPA2 pappalysin 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PKNOX2 PBX/knotted 1 homeobox 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB6A RAB6A, member RAS oncogene family
RANBP3 RAN binding protein 3
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RECQL5 RecQ protein-like 5
RHO rhodopsin
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC39A9 solute carrier family 39, member 9
SOCS1 suppressor of cytokine signaling 1
SPRR1A small proline-rich protein 1A
SRRT serrate, RNA effector molecule
TBR1 T-box, brain, 1
TBX5 T-box 5
TCP10 t-complex 10
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNS1 tensin 1
TONSL tonsoku-like, DNA repair protein
TP53TG5 TP53 target 5
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TTN titin
UHRF1BP1L UHRF1 binding protein 1-like
VAV2 vav 2 guanine nucleotide exchange factor
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
ZBED4 zinc finger, BED-type containing 4
ZNF219 zinc finger protein 219
ZNF268 zinc finger protein 268
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
AMT aminomethyltransferase
ARMCX4 armadillo repeat containing, X-linked 4
AURKC aurora kinase C
AXIN1 axin 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BBC3 BCL2 binding component 3
C17ORF53 chromosome 17 open reading frame 53
C1ORF112 chromosome 1 open reading frame 112
C7ORF43 chromosome 7 open reading frame 43
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCL27 chemokine (C-C motif) ligand 27
CCNO cyclin O
CD101 CD101 molecule
CD82 CD82 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP170B centrosomal protein 170B
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COBL cordon-bleu WH2 repeat protein
CORT cortistatin
CSF1R colony stimulating factor 1 receptor
DEAF1 DEAF1 transcription factor
EFNB1 ephrin-B1
EGF epidermal growth factor
FAM53B family with sequence similarity 53, member B
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGF23 fibroblast growth factor 23
GEMIN8 gem (nuclear organelle) associated protein 8
GSTCD glutathione S-transferase, C-terminal domain containing
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H3C histone cluster 1, H3c
HIST1H4E histone cluster 1, H4e
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IMPACT impact RWD domain protein
INPPL1 inositol polyphosphate phosphatase-like 1
JUNB jun B proto-oncogene
KCTD7 potassium channel tetramerization domain containing 7
LIMD2 LIM domain containing 2
LOC100287590 uncharacterized LOC100287590
LRP3 low density lipoprotein receptor-related protein 3
LTC4S leukotriene C4 synthase
LY86 lymphocyte antigen 86
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MN1 meningioma (disrupted in balanced translocation) 1
MOCS3 molybdenum cofactor synthesis 3
MOXD1 monooxygenase, DBH-like 1
MRPL44 mitochondrial ribosomal protein L44
MYO1F myosin IF
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5M 5',3'-nucleotidase, mitochondrial
NTSR1 neurotensin receptor 1 (high affinity)
PCDHA9 protocadherin alpha 9
PICK1 protein interacting with PRKCA 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLD3 phospholipase D family, member 3
PRR7 proline rich 7 (synaptic)
PRSS22 protease, serine, 22
PUS1 pseudouridylate synthase 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAA4 serum amyloid A4, constitutive
SLC12A8 solute carrier family 12, member 8
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMR3A submaxillary gland androgen regulated protein 3A
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNORA21 small nucleolar RNA, H/ACA box 21
SPRYD7 SPRY domain containing 7
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SUN2 Sad1 and UNC84 domain containing 2
TMEM132A transmembrane protein 132A
TMEM180 transmembrane protein 180
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VWA1 von Willebrand factor A domain containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZFHX3 zinc finger homeobox 3
ZNF222 zinc finger protein 222
ZNF253 zinc finger protein 253
ZNF282 zinc finger protein 282
ZNF667 zinc finger protein 667
ZNF668 zinc finger protein 668
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862