bepridil-1274 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bepridil-1274 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKTIP AKT interacting protein
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ATAT1 alpha tubulin acetyltransferase 1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BAD BCL2-associated agonist of cell death
BMPR1A bone morphogenetic protein receptor, type IA
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCNT2 cyclin T2
CDC14A cell division cycle 14A
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH8 cadherin 8, type 2
CDK3 cyclin-dependent kinase 3
CDYL chromodomain protein, Y-like
CENPO centromere protein O
CSNK1G1 casein kinase 1, gamma 1
CYHR1 cysteine/histidine-rich 1
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
ELL2 elongation factor, RNA polymerase II, 2
ELSPBP1 epididymal sperm binding protein 1
EVA1B eva-1 homolog B (C. elegans)
FAM114A1 family with sequence similarity 114, member A1
FAM188A family with sequence similarity 188, member A
FKBP8 FK506 binding protein 8, 38kDa
FLNB filamin B, beta
FZD7 frizzled class receptor 7
GK glycerol kinase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNS glucosamine (N-acetyl)-6-sulfatase
GRSF1 G-rich RNA sequence binding factor 1
HABP4 hyaluronan binding protein 4
HDAC7 histone deacetylase 7
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
IFT74 intraflagellar transport 74
IGFBP5 insulin-like growth factor binding protein 5
INF2 inverted formin, FH2 and WH2 domain containing
IQSEC2 IQ motif and Sec7 domain 2
KLHL28 kelch-like family member 28
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LAMA2 laminin, alpha 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP2K7 mitogen-activated protein kinase kinase 7
MCTP2 multiple C2 domains, transmembrane 2
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MTRF1L mitochondrial translational release factor 1-like
MVD mevalonate (diphospho) decarboxylase
MYO1B myosin IB
NARFL nuclear prelamin A recognition factor-like
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRP1 neuropilin 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAPPA2 pappalysin 2
PCDHGA8 protocadherin gamma subfamily A, 8
PCGF2 polycomb group ring finger 2
PDE4DIP phosphodiesterase 4D interacting protein
PDE8A phosphodiesterase 8A
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PML promyelocytic leukemia
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB3D RAB3D, member RAS oncogene family
RANBP1 RAN binding protein 1
RBPMS RNA binding protein with multiple splicing
RGS10 regulator of G-protein signaling 10
RHOD ras homolog family member D
RIMS2 regulating synaptic membrane exocytosis 2
RIN3 Ras and Rab interactor 3
RUFY3 RUN and FYVE domain containing 3
SCAMP1 secretory carrier membrane protein 1
SCAMP5 secretory carrier membrane protein 5
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SUGP1 SURP and G patch domain containing 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBXAS1 thromboxane A synthase 1 (platelet)
TET3 tet methylcytosine dioxygenase 3
TGFBR3 transforming growth factor, beta receptor III
TLK1 tousled-like kinase 1
TMEM63A transmembrane protein 63A
TSC22D3 TSC22 domain family, member 3
TSC22D4 TSC22 domain family, member 4
TSPAN13 tetraspanin 13
UTRN utrophin
VDAC3 voltage-dependent anion channel 3
VSIG10 V-set and immunoglobulin domain containing 10
WDR91 WD repeat domain 91
WDTC1 WD and tetratricopeptide repeats 1
ZNF133 zinc finger protein 133
ZNF197 zinc finger protein 197
ZNF45 zinc finger protein 45

decreased expression

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
AIM2 absent in melanoma 2
AMPD2 adenosine monophosphate deaminase 2
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASAP1-IT1 ASAP1 intronic transcript 1
ASTE1 asteroid homolog 1 (Drosophila)
ATAD3A ATPase family, AAA domain containing 3A
ATAD5 ATPase family, AAA domain containing 5
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BRIX1 BRX1, biogenesis of ribosomes
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAPN15 calpain 15
CBR1 carbonyl reductase 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC86 coiled-coil domain containing 86
CCDC88C coiled-coil domain containing 88C
CD3EAP CD3e molecule, epsilon associated protein
CDC37L1 cell division cycle 37-like 1
CECR1 cat eye syndrome chromosome region, candidate 1
CHKB choline kinase beta
CHST10 carbohydrate sulfotransferase 10
DEPDC1 DEP domain containing 1
DOK2 docking protein 2, 56kDa
DPY19L2P2 DPY19L2 pseudogene 2
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAM53B family with sequence similarity 53, member B
FAM57A family with sequence similarity 57, member A
FBXL15 F-box and leucine-rich repeat protein 15
FHL3 four and a half LIM domains 3
FLCN folliculin
FYCO1 FYVE and coiled-coil domain containing 1
GSTZ1 glutathione S-transferase zeta 1
HCAR3 hydroxycarboxylic acid receptor 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HP haptoglobin
IFT81 intraflagellar transport 81
IGFLR1 IGF-like family receptor 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IP6K1 inositol hexakisphosphate kinase 1
LLGL2 lethal giant larvae homolog 2 (Drosophila)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK12 mitogen-activated protein kinase 12
MCOLN1 mucolipin 1
METTL8 methyltransferase like 8
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MTCH2 mitochondrial carrier 2
MTG1 mitochondrial ribosome-associated GTPase 1
MYO19 myosin XIX
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NABP2 nucleic acid binding protein 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOD1 nucleotide-binding oligomerization domain containing 1
OR7E37P olfactory receptor, family 7, subfamily E, member 37 pseudogene
PAGR1 PAXIP1 associated glutamate-rich protein 1
PARG poly (ADP-ribose) glycohydrolase
PCID2 PCI domain containing 2
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PEX26 peroxisomal biogenesis factor 26
POR P450 (cytochrome) oxidoreductase
PTGES2 prostaglandin E synthase 2
REEP4 receptor accessory protein 4
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIOK2 RIO kinase 2
RNF123 ring finger protein 123
RPAP1 RNA polymerase II associated protein 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRAS related RAS viral (r-ras) oncogene homolog
SCAMP3 secretory carrier membrane protein 3
SDAD1 SDA1 domain containing 1
SDF2L1 stromal cell-derived factor 2-like 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SNIP1 Smad nuclear interacting protein 1
SPA17 sperm autoantigenic protein 17
SREK1IP1 SREK1-interacting protein 1
STBD1 starch binding domain 1
STRN4 striatin, calmodulin binding protein 4
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TERT telomerase reverse transcriptase
TESC tescalcin
THEM6 thioesterase superfamily member 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRIM26 tripartite motif containing 26
TRIM66 tripartite motif containing 66
USP36 ubiquitin specific peptidase 36
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF354A zinc finger protein 354A
ZNF37BP zinc finger protein 37B, pseudogene
ZNF536 zinc finger protein 536
ZNF862 zinc finger protein 862