bepridil-2629 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the bepridil-2629 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADAMTSL2 ADAMTS-like 2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ARC activity-regulated cytoskeleton-associated protein
ATF3 activating transcription factor 3
BCL2L1 BCL2-like 1
BHLHE40 basic helix-loop-helix family, member e40
C17ORF59 chromosome 17 open reading frame 59
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACYBP calcyclin binding protein
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CUL7 cullin 7
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
EGR1 early growth response 1
ELAVL2 ELAV like neuron-specific RNA binding protein 2
FBLN1 fibulin 1
FGF18 fibroblast growth factor 18
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL2 FOS-like antigen 2
FXR2 fragile X mental retardation, autosomal homolog 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GADD45A growth arrest and DNA-damage-inducible, alpha
GEM GTP binding protein overexpressed in skeletal muscle
GFER growth factor, augmenter of liver regeneration
HDAC11 histone deacetylase 11
HOXA10 homeobox A10
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
ICAM1 intercellular adhesion molecule 1
IER2 immediate early response 2
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
LAMC2 laminin, gamma 2
LPIN1 lipin 1
LRP12 low density lipoprotein receptor-related protein 12
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK8 mitogen-activated protein kinase 8
MBD2 methyl-CpG binding domain protein 2
MMP12 matrix metallopeptidase 12
MOCS1 molybdenum cofactor synthesis 1
MYL10 myosin, light chain 10, regulatory
NBL1 neuroblastoma 1, DAN family BMP antagonist
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLE1 notchless homolog 1 (Drosophila)
NOS1 nitric oxide synthase 1 (neuronal)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OASL 2'-5'-oligoadenylate synthetase-like
PARVB parvin, beta
PDE4DIP phosphodiesterase 4D interacting protein
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP5C protein phosphatase 5, catalytic subunit
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRUNE2 prune homolog 2 (Drosophila)
RBM5 RNA binding motif protein 5
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SASH1 SAM and SH3 domain containing 1
SAV1 salvador family WW domain containing protein 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SLMO1 slowmo homolog 1 (Drosophila)
SOCS3 suppressor of cytokine signaling 3
SPAG8 sperm associated antigen 8
SPATA1 spermatogenesis associated 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
TAZ tafazzin
TIGD6 tigger transposable element derived 6
TMEM53 transmembrane protein 53
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP34 ubiquitin specific peptidase 34
VEGFA vascular endothelial growth factor A
WDR59 WD repeat domain 59
ZER1 zyg-11 related, cell cycle regulator
ZFP36 ZFP36 ring finger protein
ZNF696 zinc finger protein 696
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ALS2CL ALS2 C-terminal like
ARID4A AT rich interactive domain 4A (RBP1-like)
BMP4 bone morphogenetic protein 4
C11ORF30 chromosome 11 open reading frame 30
C19ORF40 chromosome 19 open reading frame 40
C22ORF46 chromosome 22 open reading frame 46
C7ORF43 chromosome 7 open reading frame 43
CAPN5 calpain 5
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNJ cyclin J
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CERK ceramide kinase
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CST6 cystatin E/M
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DCAF17 DDB1 and CUL4 associated factor 17
DCK deoxycytidine kinase
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EXOC5 exocyst complex component 5
FAM155B family with sequence similarity 155, member B
FBXO22 F-box protein 22
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FMO4 flavin containing monooxygenase 4
GEMIN8 gem (nuclear organelle) associated protein 8
GLI3 GLI family zinc finger 3
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GTF2I general transcription factor IIi
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HOMER2 homer scaffolding protein 2
HOXC10 homeobox C10
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI35 interferon-induced protein 35
IFT22 intraflagellar transport 22
INO80D INO80 complex subunit D
IRAK4 interleukin-1 receptor-associated kinase 4
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHX1 LIM homeobox 1
LIN7A lin-7 homolog A (C. elegans)
LINS lines homolog (Drosophila)
LOC390998 ribosomal protein L10 pseudogene
LRRC61 leucine rich repeat containing 61
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAMLD1 mastermind-like domain containing 1
MAPK12 mitogen-activated protein kinase 12
MBTPS2 membrane-bound transcription factor peptidase, site 2
MED9 mediator complex subunit 9
MFAP2 microfibrillar-associated protein 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NEK11 NIMA-related kinase 11
NKX3-2 NK3 homeobox 2
NME6 NME/NM23 nucleoside diphosphate kinase 6
NPFFR1 neuropeptide FF receptor 1
ODF2 outer dense fiber of sperm tails 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDIA3 protein disulfide isomerase family A, member 3
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRICKLE3 prickle homolog 3 (Drosophila)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PYCRL pyrroline-5-carboxylate reductase-like
RIBC2 RIB43A domain with coiled-coils 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF123 ring finger protein 123
RNF170 ring finger protein 170
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFT2D2 SFT2 domain containing 2
SIRT6 sirtuin 6
SLC16A6 solute carrier family 16, member 6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAI2 snail family zinc finger 2
SOWAHC sosondowah ankyrin repeat domain family member C
THRAP3 thyroid hormone receptor associated protein 3
TICAM1 toll-like receptor adaptor molecule 1
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMEM180 transmembrane protein 180
TPST2 tyrosylprotein sulfotransferase 2
TTC23 tetratricopeptide repeat domain 23
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
VGF VGF nerve growth factor inducible
ZMYM1 zinc finger, MYM-type 1
ZMYM3 zinc finger, MYM-type 3
ZNF205 zinc finger protein 205
ZNF324 zinc finger protein 324
ZNF43 zinc finger protein 43
ZNF574 zinc finger protein 574
ZNF675 zinc finger protein 675
ZSCAN31 zinc finger and SCAN domain containing 31