| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
196 genes differentially expressed following the berberine-2770 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CAPN5 | calpain 5 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COL5A1 | collagen, type V, alpha 1 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CRMP1 | collapsin response mediator protein 1 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CXXC4 | CXXC finger protein 4 |
| DAGLA | diacylglycerol lipase, alpha |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| E2F5 | E2F transcription factor 5, p130-binding |
| ECE1 | endothelin converting enzyme 1 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EPHB6 | EPH receptor B6 |
| FBLN1 | fibulin 1 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FRAS1 | Fraser extracellular matrix complex subunit 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| HAP1 | huntingtin-associated protein 1 |
| HMGA1 | high mobility group AT-hook 1 |
| HOXA11 | homeobox A11 |
| IDS | iduronate 2-sulfatase |
| IGHM | immunoglobulin heavy constant mu |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INHBE | inhibin, beta E |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KDM5A | lysine (K)-specific demethylase 5A |
| KHSRP | KH-type splicing regulatory protein |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC729164 | hCG1732469 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LRRC23 | leucine rich repeat containing 23 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MBTD1 | mbt domain containing 1 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MYL10 | myosin, light chain 10, regulatory |
| MZF1 | myeloid zinc finger 1 |
| NF2 | neurofibromin 2 (merlin) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCDHA5 | protocadherin alpha 5 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PHF20 | PHD finger protein 20 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLK3 | polo-like kinase 3 |
| PLTP | phospholipid transfer protein |
| POU2F2 | POU class 2 homeobox 2 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRF1 | perforin 1 (pore forming protein) |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PRR4 | proline rich 4 (lacrimal) |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RFXAP | regulatory factor X-associated protein |
| RRBP1 | ribosome binding protein 1 |
| RUFY3 | RUN and FYVE domain containing 3 |
| S100A8 | S100 calcium binding protein A8 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SH2B1 | SH2B adaptor protein 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STK24 | serine/threonine kinase 24 |
| SYNJ2 | synaptojanin 2 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TAS2R1 | taste receptor, type 2, member 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TFF2 | trefoil factor 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TPMT | thiopurine S-methyltransferase |
| TRBC1 | T cell receptor beta constant 1 |
| VEGFA | vascular endothelial growth factor A |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WSB1 | WD repeat and SOCS box containing 1 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF3 | zinc finger protein 3 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADCY6 | adenylate cyclase 6 |
| ADCY7 | adenylate cyclase 7 |
| AEN | apoptosis enhancing nuclease |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| B9D2 | B9 protein domain 2 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CBX7 | chromobox homolog 7 |
| CCDC68 | coiled-coil domain containing 68 |
| CCDC92 | coiled-coil domain containing 92 |
| CCNT1 | cyclin T1 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CHM | choroideremia (Rab escort protein 1) |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CTSV | cathepsin V |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPPK1 | epiplakin 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| FAM131A | family with sequence similarity 131, member A |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM212B | family with sequence similarity 212, member B |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXN2 | forkhead box N2 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FZD4 | frizzled class receptor 4 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GAN | gigaxonin |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPX2 | glutathione peroxidase 2 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HSPA1L | heat shock 70kDa protein 1-like |
| HYI | hydroxypyruvate isomerase (putative) |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KLC2 | kinesin light chain 2 |
| KLHL25 | kelch-like family member 25 |
| KLHL26 | kelch-like family member 26 |
| LAMA3 | laminin, alpha 3 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTCL1 | microtubule crosslinking factor 1 |
| MYO1F | myosin IF |
| NOL12 | nucleolar protein 12 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OLFML3 | olfactomedin-like 3 |
| ORC1 | origin recognition complex, subunit 1 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PGP | phosphoglycolate phosphatase |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAD9A | RAD9 homolog A (S. pombe) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM38 | RNA binding motif protein 38 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF2 | ring finger protein 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SHPK | sedoheptulokinase |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| STX1A | syntaxin 1A (brain) |
| TCP10 | t-complex 10 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMC5 | transmembrane channel-like 5 |
| TMEM180 | transmembrane protein 180 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TXNIP | thioredoxin interacting protein |
| WDR76 | WD repeat domain 76 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF639 | zinc finger protein 639 |
