bergenin-2726 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bergenin-2726 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGMAT agmatine ureohydrolase (agmatinase)
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ANO2 anoctamin 2, calcium activated chloride channel
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BCL2L2 BCL2-like 2
BDNF brain-derived neurotrophic factor
C10ORF95 chromosome 10 open reading frame 95
CCDC121 coiled-coil domain containing 121
CCL22 chemokine (C-C motif) ligand 22
CD36 CD36 molecule (thrombospondin receptor)
CD84 CD84 molecule
CEP41 centrosomal protein 41kDa
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNOT4 CCR4-NOT transcription complex, subunit 4
COPZ2 coatomer protein complex, subunit zeta 2
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTGF connective tissue growth factor
DLK2 delta-like 2 homolog (Drosophila)
DMP1 dentin matrix acidic phosphoprotein 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPYSL3 dihydropyrimidinase-like 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELL2 elongation factor, RNA polymerase II, 2
EPS8L1 EPS8-like 1
ERAP1 endoplasmic reticulum aminopeptidase 1
EVA1B eva-1 homolog B (C. elegans)
FAM212B family with sequence similarity 212, member B
FERMT1 fermitin family member 1
FGFR1 fibroblast growth factor receptor 1
FLRT1 fibronectin leucine rich transmembrane protein 1
FOSL2 FOS-like antigen 2
G0S2 G0/G1 switch 2
GATA3 GATA binding protein 3
GHRHR growth hormone releasing hormone receptor
GJD2 gap junction protein, delta 2, 36kDa
HLA-F major histocompatibility complex, class I, F
HYAL1 hyaluronoglucosaminidase 1
ICA1 islet cell autoantigen 1, 69kDa
ICOS inducible T-cell co-stimulator
IFNA17 interferon, alpha 17
IGL immunoglobulin lambda locus
INPP5K inositol polyphosphate-5-phosphatase K
KLF6 Kruppel-like factor 6
LENEP lens epithelial protein
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LINC00652 long intergenic non-protein coding RNA 652
LMTK1 lemur tail kinase 1
LPPR3 lipid phosphate phosphatase-related protein type 3
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MDM4 MDM4, p53 regulator
MXD4 MAX dimerization protein 4
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOD2 nucleotide-binding oligomerization domain containing 2
NPPA natriuretic peptide A
PBRM1 polybromo 1
PKD2L1 polycystic kidney disease 2-like 1
PLCD1 phospholipase C, delta 1
PLCG1 phospholipase C, gamma 1
PLK4 polo-like kinase 4
PRLH prolactin releasing hormone
PTPRF protein tyrosine phosphatase, receptor type, F
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PYHIN1 pyrin and HIN domain family, member 1
RAD51B RAD51 paralog B
SCGN secretagogin, EF-hand calcium binding protein
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SIRT4 sirtuin 4
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SOX15 SRY (sex determining region Y)-box 15
SPON1 spondin 1, extracellular matrix protein
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRSF5 serine/arginine-rich splicing factor 5
SSTR2 somatostatin receptor 2
ST7L suppression of tumorigenicity 7 like
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBKBP1 TBK1 binding protein 1
TEX40 testis expressed 40
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TRIM62 tripartite motif containing 62
TTC38 tetratricopeptide repeat domain 38
UGCG UDP-glucose ceramide glucosyltransferase
WDR25 WD repeat domain 25
WDR55 WD repeat domain 55
YTHDC2 YTH domain containing 2
ZNF137P zinc finger protein 137, pseudogene
ZNF614 zinc finger protein 614

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
APOC4 apolipoprotein C-IV
AQP9 aquaporin 9
ARID5A AT rich interactive domain 5A (MRF1-like)
ARL15 ADP-ribosylation factor-like 15
ARMCX4 armadillo repeat containing, X-linked 4
ARSB arylsulfatase B
BMP15 bone morphogenetic protein 15
BNC2 basonuclin 2
C16ORF45 chromosome 16 open reading frame 45
C22ORF46 chromosome 22 open reading frame 46
CASS4 Cas scaffolding protein family member 4
CBX4 chromobox homolog 4
CCDC57 coiled-coil domain containing 57
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CFAP45 cilia and flagella associated protein 45
CLDN7 claudin 7
CLIP2 CAP-GLY domain containing linker protein 2
COQ6 coenzyme Q6 monooxygenase
CORT cortistatin
CRYGC crystallin, gamma C
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DPYS dihydropyrimidinase
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EYA3 EYA transcriptional coactivator and phosphatase 3
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
FLT4 fms-related tyrosine kinase 4
FOXD1 forkhead box D1
FOXO4 forkhead box O4
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC3 glypican 3
GPR75 G protein-coupled receptor 75
GRIP2 glutamate receptor interacting protein 2
GRPR gastrin-releasing peptide receptor
GSTT1 glutathione S-transferase theta 1
HIST1H2AI histone cluster 1, H2ai
HIST1H3B histone cluster 1, H3b
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
ICAM5 intercellular adhesion molecule 5, telencephalin
IDI2-AS1 IDI2 antisense RNA 1
IFNA14 interferon, alpha 14
IL2 interleukin 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLHL36 kelch-like family member 36
KPNA5 karyopherin alpha 5 (importin alpha 6)
LOC257152 uncharacterized LOC257152
LTBP3 latent transforming growth factor beta binding protein 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAB21L1 mab-21-like 1 (C. elegans)
MAGEF1 melanoma antigen family F1
MAGEH1 melanoma antigen family H1
MAPK8 mitogen-activated protein kinase 8
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MEP1B meprin A, beta
METTL21B methyltransferase like 21B
MRPL44 mitochondrial ribosomal protein L44
MTSS1L metastasis suppressor 1-like
MYH15 myosin, heavy chain 15
MYOZ3 myozenin 3
NAG18 NAG18 mRNA
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NEUROD4 neuronal differentiation 4
NIPAL2 NIPA-like domain containing 2
NNAT neuronatin
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PIPOX pipecolic acid oxidase
PKD2L2 polycystic kidney disease 2-like 2
POLH polymerase (DNA directed), eta
POM121 POM121 transmembrane nucleoporin
PRKCZ protein kinase C, zeta
RAP1GAP2 RAP1 GTPase activating protein 2
RCAN3 RCAN family member 3
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHBDD3 rhomboid domain containing 3
RIBC2 RIB43A domain with coiled-coils 2
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCN10A sodium channel, voltage gated, type X alpha subunit
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMR3A submaxillary gland androgen regulated protein 3A
SPATA1 spermatogenesis associated 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STARD13 StAR-related lipid transfer (START) domain containing 13
SUSD5 sushi domain containing 5
TAS2R10 taste receptor, type 2, member 10
TBL1Y transducin (beta)-like 1, Y-linked
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEAD3 TEA domain family member 3
TIGD6 tigger transposable element derived 6
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBB2A tubulin, beta 2A class IIa
WDR33 WD repeat domain 33