bergenin-5870 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bergenin-5870 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ADGRL1 adhesion G protein-coupled receptor L1
AKAP5 A kinase (PRKA) anchor protein 5
ARMC4 armadillo repeat containing 4
ASIC3 acid sensing (proton gated) ion channel 3
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BMP7 bone morphogenetic protein 7
BTG2 BTG family, member 2
C17ORF53 chromosome 17 open reading frame 53
CAMK1 calcium/calmodulin-dependent protein kinase I
CD58 CD58 molecule
CD68 CD68 molecule
CD70 CD70 molecule
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CEP295 centrosomal protein 295kDa
CEP68 centrosomal protein 68kDa
CLCA2 chloride channel accessory 2
CLDN17 claudin 17
CNTLN centlein, centrosomal protein
COL11A2 collagen, type XI, alpha 2
COMT catechol-O-methyltransferase
CUZD1 CUB and zona pellucida-like domains 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
GPC4 glypican 4
HIRA histone cell cycle regulator
HIST1H4D histone cluster 1, H4d
HIST1H4E histone cluster 1, H4e
HOXB2 homeobox B2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KIAA0922 KIAA0922
KIAA1107 KIAA1107
LDB3 LIM domain binding 3
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LMAN1 lectin, mannose-binding, 1
LMF1 lipase maturation factor 1
LMF2 lipase maturation factor 2
LMO7 LIM domain 7
LRRK1 leucine-rich repeat kinase 1
MANBA mannosidase, beta A, lysosomal
MAP2K2 mitogen-activated protein kinase kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MST1 macrophage stimulating 1
MYLK myosin light chain kinase
N4BP2L1 NEDD4 binding protein 2-like 1
NCKIPSD NCK interacting protein with SH3 domain
NCOR1 nuclear receptor corepressor 1
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEK11 NIMA-related kinase 11
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL2 NIPA-like domain containing 2
NUDCD3 NudC domain containing 3
PAOX polyamine oxidase (exo-N4-amino)
PARM1 prostate androgen-regulated mucin-like protein 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE4DIP phosphodiesterase 4D interacting protein
PMS2P4 postmeiotic segregation increased 2 pseudogene 4
PRTN3 proteinase 3
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRE protein tyrosine phosphatase, receptor type, E
QKI QKI, KH domain containing, RNA binding
RAD23B RAD23 homolog B (S. cerevisiae)
RANGAP1 Ran GTPase activating protein 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
ROM1 retinal outer segment membrane protein 1
RPS3A ribosomal protein S3A
RTEL1 regulator of telomere elongation helicase 1
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERHL2 serine hydrolase-like 2
SLC35F6 solute carrier family 35, member F6
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SNW1 SNW domain containing 1
SOSTDC1 sclerostin domain containing 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SSTR2 somatostatin receptor 2
STK24 serine/threonine kinase 24
STX3 syntaxin 3
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBC1D2B TBC1 domain family, member 2B
TLE4 transducin-like enhancer of split 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN8 tetraspanin 8
TTF1 transcription termination factor, RNA polymerase I
TUBA4B tubulin, alpha 4b
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
UTRN utrophin
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WDR62 WD repeat domain 62
ZFHX2 zinc finger homeobox 2
ZFP36L2 ZFP36 ring finger protein-like 2
ZHX3 zinc fingers and homeoboxes 3
ZNF287 zinc finger protein 287
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMDHD2 amidohydrolase domain containing 2
APLP1 amyloid beta (A4) precursor-like protein 1
APOLD1 apolipoprotein L domain containing 1
ASB7 ankyrin repeat and SOCS box containing 7
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
C17ORF70 chromosome 17 open reading frame 70
C1ORF112 chromosome 1 open reading frame 112
C1ORF115 chromosome 1 open reading frame 115
C5 complement component 5
C6ORF47 chromosome 6 open reading frame 47
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDON cell adhesion associated, oncogene regulated
CHMP6 charged multivesicular body protein 6
CHST10 carbohydrate sulfotransferase 10
CLSPN claspin
CTSD cathepsin D
DCAF13 DDB1 and CUL4 associated factor 13
DCAF17 DDB1 and CUL4 associated factor 17
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
ECM1 extracellular matrix protein 1
EFNA3 ephrin-A3
FAM120C family with sequence similarity 120C
FANCF Fanconi anemia, complementation group F
FBXL15 F-box and leucine-rich repeat protein 15
FEM1C fem-1 homolog c (C. elegans)
FKBPL FK506 binding protein like
FRS3 fibroblast growth factor receptor substrate 3
GCHFR GTP cyclohydrolase I feedback regulator
GLCE glucuronic acid epimerase
GPATCH3 G patch domain containing 3
GPR137B G protein-coupled receptor 137B
GTPBP2 GTP binding protein 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1E histone cluster 1, H1e
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HOXA1 homeobox A1
ITPKB inositol-trisphosphate 3-kinase B
KCTD15 potassium channel tetramerization domain containing 15
KIAA0196 KIAA0196
KIAA0894 KIAA0894 protein
KRT4 keratin 4, type II
L2HGDH L-2-hydroxyglutarate dehydrogenase
LIMS2 LIM and senescent cell antigen-like domains 2
LOC100286895 cell division cycle 27 homolog pseudogene
LRP3 low density lipoprotein receptor-related protein 3
LRRC15 leucine rich repeat containing 15
LYPD3 LY6/PLAUR domain containing 3
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP6D1 MAP6 domain containing 1
MED15 mediator complex subunit 15
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
NSD1 nuclear receptor binding SET domain protein 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OCEL1 occludin/ELL domain containing 1
PDE12 phosphodiesterase 12
PHGDH phosphoglycerate dehydrogenase
PRPH peripherin
PRSS16 protease, serine, 16 (thymus)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTTG3P pituitary tumor-transforming 3, pseudogene
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB27B RAB27B, member RAS oncogene family
RASA2 RAS p21 protein activator 2
REPS2 RALBP1 associated Eps domain containing 2
RIBC2 RIB43A domain with coiled-coils 2
RIN1 Ras and Rab interactor 1
RNF122 ring finger protein 122
RPL10L ribosomal protein L10-like
SETD8 SET domain containing (lysine methyltransferase) 8
SH3BGR SH3 domain binding glutamate-rich protein
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SND1-IT1 SND1 intronic transcript 1
SNORA21 small nucleolar RNA, H/ACA box 21
TBC1D19 TBC1 domain family, member 19
TDRD7 tudor domain containing 7
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM183A transmembrane protein 183A
TPCN1 two pore segment channel 1
TRAIP TRAF interacting protein
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTBK2 tau tubulin kinase 2
TTC23 tetratricopeptide repeat domain 23
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
VEZT vezatin, adherens junctions transmembrane protein
WNT10B wingless-type MMTV integration site family, member 10B
ZFAND3 zinc finger, AN1-type domain 3
ZNF408 zinc finger protein 408
ZNF552 zinc finger protein 552