bergenin-7224 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the bergenin-7224 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ART1 ADP-ribosyltransferase 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BTF3P11 basic transcription factor 3 pseudogene 11
CA12 carbonic anhydrase XII
CAPN5 calpain 5
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD86 CD86 molecule
CHD5 chromodomain helicase DNA binding protein 5
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
COL3A1 collagen, type III, alpha 1
CORT cortistatin
CRTAC1 cartilage acidic protein 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTGF connective tissue growth factor
DCN decorin
DGCR8 DGCR8 microprocessor complex subunit
DRD1 dopamine receptor D1
ELP6 elongator acetyltransferase complex subunit 6
FAM214B family with sequence similarity 214, member B
FBXO22 F-box protein 22
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGFR3 fibroblast growth factor receptor 3
FYB FYN binding protein
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GFAP glial fibrillary acidic protein
GPR157 G protein-coupled receptor 157
GRPR gastrin-releasing peptide receptor
HMOX1 heme oxygenase 1
HR hair growth associated
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IFT122 intraflagellar transport 122
IFT27 intraflagellar transport 27
KAT8 K(lysine) acetyltransferase 8
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KRT83 keratin 83, type II
LINC00341 long intergenic non-protein coding RNA 341
LOC100286895 cell division cycle 27 homolog pseudogene
MBNL2 muscleblind-like splicing regulator 2
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCR2 natural cytotoxicity triggering receptor 2
NECAB2 N-terminal EF-hand calcium binding protein 2
NFX1 nuclear transcription factor, X-box binding 1
PAIP2B poly(A) binding protein interacting protein 2B
PAX2 paired box 2
PAX3 paired box 3
PDE10A phosphodiesterase 10A
PDLIM5 PDZ and LIM domain 5
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKD2L1 polycystic kidney disease 2-like 1
PLK4 polo-like kinase 4
POLL polymerase (DNA directed), lambda
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTPRA protein tyrosine phosphatase, receptor type, A
RECQL5 RecQ protein-like 5
RFPL1 ret finger protein-like 1
RPGR retinitis pigmentosa GTPase regulator
SCN10A sodium channel, voltage gated, type X alpha subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNX13 sorting nexin 13
SPEG SPEG complex locus
SSPN sarcospan
STOML1 stomatin (EPB72)-like 1
TBL2 transducin (beta)-like 2
TDO2 tryptophan 2,3-dioxygenase
TLR2 toll-like receptor 2
TMEM212 transmembrane protein 212
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TOP3A topoisomerase (DNA) III alpha
TOP3B topoisomerase (DNA) III beta
TOX thymocyte selection-associated high mobility group box
TRDMT1 tRNA aspartic acid methyltransferase 1
UBTD1 ubiquitin domain containing 1
UPK2 uroplakin 2
USP2 ubiquitin specific peptidase 2
VIPR1 vasoactive intestinal peptide receptor 1
YTHDC2 YTH domain containing 2
YY2 YY2 transcription factor
ZER1 zyg-11 related, cell cycle regulator
ZNF254 zinc finger protein 254
ZNF516 zinc finger protein 516
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABHD14A abhydrolase domain containing 14A
ACTN4 actinin, alpha 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAM15 ADAM metallopeptidase domain 15
ADGRE5 adhesion G protein-coupled receptor E5
ALPK1 alpha-kinase 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATG2A autophagy related 2A
AXIN1 axin 1
BBS1 Bardet-Biedl syndrome 1
C2ORF44 chromosome 2 open reading frame 44
C4ORF29 chromosome 4 open reading frame 29
C5 complement component 5
CALCOCO1 calcium binding and coiled-coil domain 1
CAMKMT calmodulin-lysine N-methyltransferase
CAMTA2 calmodulin binding transcription activator 2
CCDC91 coiled-coil domain containing 91
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGKD diacylglycerol kinase, delta 130kDa
DUSP8 dual specificity phosphatase 8
ELOVL4 ELOVL fatty acid elongase 4
EPHA2 EPH receptor A2
FAIM Fas apoptotic inhibitory molecule
FBXO46 F-box protein 46
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGGY FGGY carbohydrate kinase domain containing
FHOD1 formin homology 2 domain containing 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GID4 GID complex subunit 4
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HPS6 Hermansky-Pudlak syndrome 6
IL17RA interleukin 17 receptor A
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIF16B kinesin family member 16B
KLHL26 kelch-like family member 26
LAMA3 laminin, alpha 3
LHX6 LIM homeobox 6
LNPEP leucyl/cystinyl aminopeptidase
LOC257152 uncharacterized LOC257152
LOC730101 uncharacterized LOC730101
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC20 leucine rich repeat containing 20
MAGEH1 melanoma antigen family H1
MANBA mannosidase, beta A, lysosomal
MANEA mannosidase, endo-alpha
MAPKBP1 mitogen-activated protein kinase binding protein 1
MICALL2 MICAL-like 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MOCS2 molybdenum cofactor synthesis 2
MORC3 MORC family CW-type zinc finger 3
MXD3 MAX dimerization protein 3
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NKAIN1 Na+/K+ transporting ATPase interacting 1
NRSN2 neurensin 2
PAQR6 progestin and adipoQ receptor family member VI
PARP16 poly (ADP-ribose) polymerase family, member 16
PGP phosphoglycolate phosphatase
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PILRB paired immunoglobin-like type 2 receptor beta
PKD2 polycystic kidney disease 2 (autosomal dominant)
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
RBL1 retinoblastoma-like 1
SAV1 salvador family WW domain containing protein 1
SCAI suppressor of cancer cell invasion
SCD5 stearoyl-CoA desaturase 5
SCG2 secretogranin II
SCPEP1 serine carboxypeptidase 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIDT1 SID1 transmembrane family, member 1
SIK1 salt-inducible kinase 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMAD7 SMAD family member 7
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD3 StAR-related lipid transfer (START) domain containing 3
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TCTN2 tectonic family member 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TWF2 twinfilin actin binding protein 2
UPP1 uridine phosphorylase 1
URGCP upregulator of cell proliferation
USP18 ubiquitin specific peptidase 18
VAV1 vav 1 guanine nucleotide exchange factor
ZNF276 zinc finger protein 276
ZNF35 zinc finger protein 35
ZNF492 zinc finger protein 492
ZSCAN31 zinc finger and SCAN domain containing 31
ZW10 zw10 kinetochore protein
ZXDC ZXD family zinc finger C