best Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

188 genes co-occuring with the biological term best in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD12 abhydrolase domain containing 12
ABHD6 abhydrolase domain containing 6
ACE angiotensin I converting enzyme
AFP alpha-fetoprotein
AGO1 argonaute RISC catalytic component 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHSG alpha-2-HS-glycoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
AMH anti-Mullerian hormone
AMPD1 adenosine monophosphate deaminase 1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOE apolipoprotein E
AR androgen receptor
ARRB2 arrestin, beta 2
ATF2 activating transcription factor 2
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BEST1 bestrophin 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C1QB complement component 1, q subcomponent, B chain
CACNG3 calcium channel, voltage-dependent, gamma subunit 3
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD24 CD24 molecule
CD38 CD38 molecule
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC73 cell division cycle 73
CDKN2A cyclin-dependent kinase inhibitor 2A
CGB chorionic gonadotropin, beta polypeptide
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CMA1 chymase 1, mast cell
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COL1A1 collagen, type I, alpha 1
COL25A1 collagen, type XXV, alpha 1
COMT catechol-O-methyltransferase
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CST3 cystatin C
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DHFR dihydrofolate reductase
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DRD4 dopamine receptor D4
DROSHA drosha, ribonuclease type III
EGFR epidermal growth factor receptor
EP300 E1A binding protein p300
ERAP2 endoplasmic reticulum aminopeptidase 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC1 excision repair cross-complementation group 1
FBN1 fibrillin 1
FGF2 fibroblast growth factor 2 (basic)
FGF21 fibroblast growth factor 21
FLT3 fms-related tyrosine kinase 3
GAB2 GRB2-associated binding protein 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GANAB glucosidase, alpha; neutral AB
GATA3 GATA binding protein 3
GFAP glial fibrillary acidic protein
GHRL ghrelin/obestatin prepropeptide
GLP1R glucagon-like peptide 1 receptor
GM2AP1 GM2 ganglioside activator pseudogene 1
HAVCR1 hepatitis A virus cellular receptor 1
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBE1 hemoglobin, epsilon 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-C major histocompatibility complex, class I, C
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HRAS Harvey rat sarcoma viral oncogene homolog
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL10 interleukin 10
IL18 interleukin 18
IL23A interleukin 23, alpha subunit p19
IL2RA interleukin 2 receptor, alpha
IL5 interleukin 5
IL6 interleukin 6
INHBB inhibin, beta B
INS insulin
ITGA6 integrin, alpha 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
L1CAM L1 cell adhesion molecule
LGALS13 lectin, galactoside-binding, soluble, 13
LGSN lengsin, lens protein with glutamine synthetase domain
LIPC lipase, hepatic
LMNA lamin A/C
LTA4H leukotriene A4 hydrolase
MAML1 mastermind-like 1 (Drosophila)
MAPT microtubule-associated protein tau
MB myoglobin
MBL2 mannose-binding lectin (protein C) 2, soluble
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCM2 minichromosome maintenance complex component 2
MKI67 marker of proliferation Ki-67
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MSX2 msh homeobox 2
MUC1 mucin 1, cell surface associated
MYP1 myopia 1 (X-linked)
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NLRP1 NLR family, pyrin domain containing 1
NPAS2 neuronal PAS domain protein 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPB natriuretic peptide B
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PAX2 paired box 2
PAX8 paired box 8
PCA3 prostate cancer associated 3 (non-protein coding)
PCLO piccolo presynaptic cytomatrix protein
PDCD10 programmed cell death 10
PEX19 peroxisomal biogenesis factor 19
PEX3 peroxisomal biogenesis factor 3
PEX5 peroxisomal biogenesis factor 5
PINK1 PTEN induced putative kinase 1
PM20D2 peptidase M20 domain containing 2
PON2 paraoxonase 2
PORCN porcupine homolog (Drosophila)
PPARA peroxisome proliferator-activated receptor alpha
PSEN2 presenilin 2
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RET ret proto-oncogene
RNASET2 ribonuclease T2
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RTN4 reticulon 4
SAA1 serum amyloid A1
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMG8 SMG8 nonsense mediated mRNA decay factor
SST somatostatin
SSTR1 somatostatin receptor 1
SSTR2 somatostatin receptor 2
SSTR5 somatostatin receptor 5
TAGLN transgelin
TES testin LIM domain protein
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TIGAR TP53 induced glycolysis regulatory phosphatase
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TPM1 tropomyosin 1 (alpha)
TPSAB1 tryptase alpha/beta 1
TREM2 triggering receptor expressed on myeloid cells 2
TRPM8 transient receptor potential cation channel, subfamily M, member 8
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VCAM1 vascular cell adhesion molecule 1
WFDC2 WAP four-disulfide core domain 2
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZNF516 zinc finger protein 516