beta-catenin destruction complex Gene Set

Dataset	GO Cellular Component Annotations 2015
Category	structural or functional annotations
Type	cellular component
Description	A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome. (Gene Ontology, GO_0030877)
External Link	http://amigo.geneontology.org/amigo/term/GO:0030877
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Genes

10 proteins localized to the beta-catenin destruction complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol	Name
APC	adenomatous polyposis coli
AXIN1	axin 1
AXIN2	axin 2
CACYBP	calcyclin binding protein
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1	catenin, beta interacting protein 1
DACT1	dishevelled-binding antagonist of beta-catenin 1
GSK3A	glycogen synthase kinase 3 alpha
GSK3B	glycogen synthase kinase 3 beta
SIAH1	siah E3 ubiquitin protein ligase 1