| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the beta-escin-3807 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| AJAP1 | adherens junctions associated protein 1 |
| APOL2 | apolipoprotein L, 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| ATF5 | activating transcription factor 5 |
| ATP10A | ATPase, class V, type 10A |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BMP2 | bone morphogenetic protein 2 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CADM1 | cell adhesion molecule 1 |
| CADM3 | cell adhesion molecule 3 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CCDC181 | coiled-coil domain containing 181 |
| CD200 | CD200 molecule |
| CD52 | CD52 molecule |
| CD6 | CD6 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| COPE | coatomer protein complex, subunit epsilon |
| CPLX2 | complexin 2 |
| CSPG4 | chondroitin sulfate proteoglycan 4 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DIO2 | deiodinase, iodothyronine, type II |
| DUSP1 | dual specificity phosphatase 1 |
| EGR1 | early growth response 1 |
| EXPH5 | exophilin 5 |
| FGF4 | fibroblast growth factor 4 |
| FLOT1 | flotillin 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GPR85 | G protein-coupled receptor 85 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3I | histone cluster 1, H3i |
| HLF | hepatic leukemia factor |
| HMOX1 | heme oxygenase 1 |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IL1RN | interleukin 1 receptor antagonist |
| IL24 | interleukin 24 |
| IL5RA | interleukin 5 receptor, alpha |
| IL6 | interleukin 6 |
| JUN | jun proto-oncogene |
| JUND | jun D proto-oncogene |
| KITLG | KIT ligand |
| LAMB4 | laminin, beta 4 |
| LPL | lipoprotein lipase |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MEGF6 | multiple EGF-like-domains 6 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NUP50 | nucleoporin 50kDa |
| OR1F2P | olfactory receptor, family 1, subfamily F, member 2, pseudogene |
| OR7A10 | olfactory receptor, family 7, subfamily A, member 10 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PGM5 | phosphoglucomutase 5 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PRKCB | protein kinase C, beta |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RAB26 | RAB26, member RAS oncogene family |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RND1 | Rho family GTPase 1 |
| RRAD | Ras-related associated with diabetes |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| STC2 | stanniocalcin 2 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TGFB1 | transforming growth factor, beta 1 |
| TLX2 | T-cell leukemia homeobox 2 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TSPAN8 | tetraspanin 8 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| UNC13A | unc-13 homolog A (C. elegans) |
| ZFPM2 | zinc finger protein, FOG family member 2 |
| ZNF235 | zinc finger protein 235 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AGO4 | argonaute RISC catalytic component 4 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AIM1 | absent in melanoma 1 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| AMT | aminomethyltransferase |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ATXN2 | ataxin 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C1R | complement component 1, r subcomponent |
| C1RL | complement component 1, r subcomponent-like |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CBX8 | chromobox homolog 8 |
| CEP83 | centrosomal protein 83kDa |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| DBF4B | DBF4 zinc finger B |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| ECM1 | extracellular matrix protein 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM184A | family with sequence similarity 184, member A |
| FAT4 | FAT atypical cadherin 4 |
| FBXO46 | F-box protein 46 |
| FMO4 | flavin containing monooxygenase 4 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GPR21 | G protein-coupled receptor 21 |
| GPR4 | G protein-coupled receptor 4 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GSDMD | gasdermin D |
| HCFC1 | host cell factor C1 |
| HDAC11 | histone deacetylase 11 |
| HOXA7 | homeobox A7 |
| HOXC10 | homeobox C10 |
| HOXC4 | homeobox C4 |
| HOXC5 | homeobox C5 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL33 | interleukin 33 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIAA0513 | KIAA0513 |
| KIAA0556 | KIAA0556 |
| KIFC3 | kinesin family member C3 |
| KLHL25 | kelch-like family member 25 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC157562 | uncharacterized LOC157562 |
| MEFV | Mediterranean fever |
| NDP | Norrie disease (pseudoglioma) |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PER3 | period circadian clock 3 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PODNL1 | podocan-like 1 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB36 | RAB36, member RAS oncogene family |
| RARS | arginyl-tRNA synthetase |
| REEP1 | receptor accessory protein 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF2 | ring finger protein 2 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPH3A | rabphilin 3A |
| SALL2 | spalt-like transcription factor 2 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SIRT6 | sirtuin 6 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SOX30 | SRY (sex determining region Y)-box 30 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TENM4 | teneurin transmembrane protein 4 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFCP2L1 | transcription factor CP2-like 1 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| THRB | thyroid hormone receptor, beta |
| TRIB2 | tribbles pseudokinase 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF219 | zinc finger protein 219 |
| ZNF334 | zinc finger protein 334 |
| ZNF552 | zinc finger protein 552 |
| ZNF573 | zinc finger protein 573 |