Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the beta-escin-4364 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACOX2 | acyl-CoA oxidase 2, branched chain |
ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
ADCK4 | aarF domain containing kinase 4 |
AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
ATF7IP | activating transcription factor 7 interacting protein |
ATP10B | ATPase, class V, type 10B |
BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
BDKRB2 | bradykinin receptor B2 |
BIRC3 | baculoviral IAP repeat containing 3 |
C11ORF30 | chromosome 11 open reading frame 30 |
C17ORF53 | chromosome 17 open reading frame 53 |
C1RL | complement component 1, r subcomponent-like |
CCKBR | cholecystokinin B receptor |
CD2 | CD2 molecule |
CD79A | CD79a molecule, immunoglobulin-associated alpha |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
CEMIP | cell migration inducing protein, hyaluronan binding |
CGA | glycoprotein hormones, alpha polypeptide |
CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
CHRNB3 | cholinergic receptor, nicotinic, beta 3 (neuronal) |
CLCA1 | chloride channel accessory 1 |
CLTA | clathrin, light chain A |
CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
CORO2B | coronin, actin binding protein, 2B |
CPA4 | carboxypeptidase A4 |
CRMP1 | collapsin response mediator protein 1 |
CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
EHF | ets homologous factor |
ELN | elastin |
ELOVL5 | ELOVL fatty acid elongase 5 |
EPS8L3 | EPS8-like 3 |
FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
GEM | GTP binding protein overexpressed in skeletal muscle |
GRIK2 | glutamate receptor, ionotropic, kainate 2 |
HIST1H2AB | histone cluster 1, H2ab |
ICOS | inducible T-cell co-stimulator |
IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
IL10 | interleukin 10 |
IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 |
INSR | insulin receptor |
ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
IZUMO4 | IZUMO family member 4 |
KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
KLF12 | Kruppel-like factor 12 |
KLF13 | Kruppel-like factor 13 |
LIF | leukemia inhibitory factor |
LOC51145 | uncharacterized LOC51145 |
LTB4R | leukotriene B4 receptor |
MATN1 | matrilin 1, cartilage matrix protein |
MAU2 | MAU2 sister chromatid cohesion factor |
MOBP | myelin-associated oligodendrocyte basic protein |
MORN1 | MORN repeat containing 1 |
MTNR1A | melatonin receptor 1A |
MXD4 | MAX dimerization protein 4 |
NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
PBX2 | pre-B-cell leukemia homeobox 2 |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
PLK3 | polo-like kinase 3 |
PLTP | phospholipid transfer protein |
POLDIP3 | polymerase (DNA-directed), delta interacting protein 3 |
PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
RAP1GAP | RAP1 GTPase activating protein |
RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
RCAN1 | regulator of calcineurin 1 |
RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
RGCC | regulator of cell cycle |
RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
SERHL2 | serine hydrolase-like 2 |
SHOX2 | short stature homeobox 2 |
SLC43A3 | solute carrier family 43, member 3 |
SOX9 | SRY (sex determining region Y)-box 9 |
SPATS2L | spermatogenesis associated, serine-rich 2-like |
SPON1 | spondin 1, extracellular matrix protein |
SPRR1A | small proline-rich protein 1A |
SVIL | supervillin |
TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
VCAN | versican |
WSCD1 | WSC domain containing 1 |
XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
ZG16 | zymogen granule protein 16 |
ZNF222 | zinc finger protein 222 |
Symbol | Name |
---|---|
ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
ALS2CL | ALS2 C-terminal like |
ARC | activity-regulated cytoskeleton-associated protein |
ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
ASAP1-IT1 | ASAP1 intronic transcript 1 |
BLNK | B-cell linker |
C14ORF79 | chromosome 14 open reading frame 79 |
C1ORF54 | chromosome 1 open reading frame 54 |
C1QB | complement component 1, q subcomponent, B chain |
C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
CA5BP1 | carbonic anhydrase VB pseudogene 1 |
CD83 | CD83 molecule |
CDADC1 | cytidine and dCMP deaminase domain containing 1 |
CDH18 | cadherin 18, type 2 |
CFHR4 | complement factor H-related 4 |
CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
CLCN6 | chloride channel, voltage-sensitive 6 |
CNTFR | ciliary neurotrophic factor receptor |
CORT | cortistatin |
CPNE7 | copine VII |
DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
DBF4B | DBF4 zinc finger B |
DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
DEPDC5 | DEP domain containing 5 |
DMTN | dematin actin binding protein |
DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
DTX2 | deltex 2, E3 ubiquitin ligase |
ELSPBP1 | epididymal sperm binding protein 1 |
EPHX2 | epoxide hydrolase 2, cytoplasmic |
ERO1LB | ERO1-like beta (S. cerevisiae) |
ETV6 | ets variant 6 |
FAM120C | family with sequence similarity 120C |
FBXO2 | F-box protein 2 |
FLRT3 | fibronectin leucine rich transmembrane protein 3 |
GFI1 | growth factor independent 1 transcription repressor |
GMPR | guanosine monophosphate reductase |
GPRC5D | G protein-coupled receptor, class C, group 5, member D |
GRAMD1C | GRAM domain containing 1C |
HDAC7 | histone deacetylase 7 |
HIST1H2AK | histone cluster 1, H2ak |
HOXA4 | homeobox A4 |
ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
IDI2-AS1 | IDI2 antisense RNA 1 |
IFT81 | intraflagellar transport 81 |
IPO8 | importin 8 |
KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
KLF2 | Kruppel-like factor 2 |
LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
LOC390998 | ribosomal protein L10 pseudogene |
LOC730101 | uncharacterized LOC730101 |
MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
MAST3 | microtubule associated serine/threonine kinase 3 |
MTCP1 | mature T-cell proliferation 1 |
NAT6 | N-acetyltransferase 6 (GCN5-related) |
NDE1 | nudE neurodevelopment protein 1 |
NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
OLFML2A | olfactomedin-like 2A |
OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
PAIP2B | poly(A) binding protein interacting protein 2B |
PARP16 | poly (ADP-ribose) polymerase family, member 16 |
PCDHB13 | protocadherin beta 13 |
PCDHB3 | protocadherin beta 3 |
PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
PLD3 | phospholipase D family, member 3 |
POU3F2 | POU class 3 homeobox 2 |
PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
PSCA | prostate stem cell antigen |
QPCT | glutaminyl-peptide cyclotransferase |
RAB36 | RAB36, member RAS oncogene family |
RNF126P1 | ring finger protein 126 pseudogene 1 |
RNF208 | ring finger protein 208 |
RPGR | retinitis pigmentosa GTPase regulator |
RPL10L | ribosomal protein L10-like |
SAYSD1 | SAYSVFN motif domain containing 1 |
SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
SETD8 | SET domain containing (lysine methyltransferase) 8 |
SGCE | sarcoglycan, epsilon |
SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
SLMO1 | slowmo homolog 1 (Drosophila) |
SOAT2 | sterol O-acyltransferase 2 |
SYNC | syncoilin, intermediate filament protein |
TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
TET3 | tet methylcytosine dioxygenase 3 |
TEX14 | testis expressed 14 |
TLR5 | toll-like receptor 5 |
TPSG1 | tryptase gamma 1 |
TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
TUBA4B | tubulin, alpha 4b |
ZFP37 | ZFP37 zinc finger protein |
ZNF134 | zinc finger protein 134 |
ZNF37BP | zinc finger protein 37B, pseudogene |
ZNF862 | zinc finger protein 862 |
ZSWIM1 | zinc finger, SWIM-type containing 1 |