| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
196 genes differentially expressed following the beta-escin-4544 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADM | adrenomedullin |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATF3 | activating transcription factor 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BMP2 | bone morphogenetic protein 2 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CACFD1 | calcium channel flower domain containing 1 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD83 | CD83 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CISH | cytokine inducible SH2-containing protein |
| CLDN1 | claudin 1 |
| CTH | cystathionine gamma-lyase |
| CTNS | cystinosin, lysosomal cystine transporter |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| CYTH1 | cytohesin 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| EGR1 | early growth response 1 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FERMT2 | fermitin family member 2 |
| FGF5 | fibroblast growth factor 5 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GK | glycerol kinase |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GRAMD1C | GRAM domain containing 1C |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GTPBP1 | GTP binding protein 1 |
| HBB | hemoglobin, beta |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H4H | histone cluster 1, H4h |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICAM1 | intercellular adhesion molecule 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL11 | interleukin 11 |
| IL1RL1 | interleukin 1 receptor-like 1 |
| IL24 | interleukin 24 |
| IL6 | interleukin 6 |
| INHBA | inhibin, beta A |
| JUN | jun proto-oncogene |
| KHSRP | KH-type splicing regulatory protein |
| KLF6 | Kruppel-like factor 6 |
| KRT17 | keratin 17, type I |
| KRT34 | keratin 34, type I |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MEGF9 | multiple EGF-like-domains 9 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NGF | nerve growth factor (beta polypeptide) |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PCDHB3 | protocadherin beta 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RGS3 | regulator of G-protein signaling 3 |
| RGS4 | regulator of G-protein signaling 4 |
| RHOB | ras homolog family member B |
| RND1 | Rho family GTPase 1 |
| RND3 | Rho family GTPase 3 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPL35A | ribosomal protein L35a |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| STC2 | stanniocalcin 2 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TGFB2 | transforming growth factor, beta 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TOP3B | topoisomerase (DNA) III beta |
| XDH | xanthine dehydrogenase |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AKIP1 | A kinase (PRKA) interacting protein 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF112 | chromosome 1 open reading frame 112 |
| C1S | complement component 1, s subcomponent |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CBX7 | chromobox homolog 7 |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCNA1 | cyclin A1 |
| CCNJ | cyclin J |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNN2 | calponin 2 |
| CNTNAP3B | contactin associated protein-like 3B |
| CORO1A | coronin, actin binding protein, 1A |
| CPNE7 | copine VII |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CTSO | cathepsin O |
| CYBRD1 | cytochrome b reductase 1 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| EFNB1 | ephrin-B1 |
| EHD3 | EH-domain containing 3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM127B | family with sequence similarity 127, member B |
| FOXN2 | forkhead box N2 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GLI3 | GLI family zinc finger 3 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GPATCH3 | G patch domain containing 3 |
| GPX2 | glutathione peroxidase 2 |
| GRPR | gastrin-releasing peptide receptor |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2AK | histone cluster 1, H2ak |
| HOXA1 | homeobox A1 |
| HOXB13 | homeobox B13 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| ICK | intestinal cell (MAK-like) kinase |
| IQCG | IQ motif containing G |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KRT8P12 | keratin 8 pseudogene 12 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAGEF1 | melanoma antigen family F1 |
| MGP | matrix Gla protein |
| MUC3B | mucin 3B, cell surface associated |
| NDP | Norrie disease (pseudoglioma) |
| NDRG4 | NDRG family member 4 |
| NME5 | NME/NM23 family member 5 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| OSMR | oncostatin M receptor |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PLCD1 | phospholipase C, delta 1 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRSS53 | protease, serine, 53 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SHROOM2 | shroom family member 2 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STAG3 | stromal antigen 3 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TBX19 | T-box 19 |
| TENM4 | teneurin transmembrane protein 4 |
| TRAF3IP1 | TNF receptor-associated factor 3 interacting protein 1 |
| UGT8 | UDP glycosyltransferase 8 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF324 | zinc finger protein 324 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF446 | zinc finger protein 446 |
| ZNF747 | zinc finger protein 747 |
| ZNF768 | zinc finger protein 768 |
| ZNF816 | zinc finger protein 816 |
