beta-escin-6050 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the beta-escin-6050 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACO2 aconitase 2, mitochondrial
ACRV1 acrosomal vesicle protein 1
ADCK4 aarF domain containing kinase 4
ADGRE2 adhesion G protein-coupled receptor E2
AFF2 AF4/FMR2 family, member 2
ARSD arylsulfatase D
ATF3 activating transcription factor 3
ATF7 activating transcription factor 7
ATN1 atrophin 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BIRC3 baculoviral IAP repeat containing 3
BST2 bone marrow stromal cell antigen 2
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF21 chromosome 11 open reading frame 21
CD177 CD177 molecule
CD200 CD200 molecule
CDK14 cyclin-dependent kinase 14
CDK6 cyclin-dependent kinase 6
CEMIP cell migration inducing protein, hyaluronan binding
CEND1 cell cycle exit and neuronal differentiation 1
CGA glycoprotein hormones, alpha polypeptide
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLCN7 chloride channel, voltage-sensitive 7
CNOT2 CCR4-NOT transcription complex, subunit 2
COL17A1 collagen, type XVII, alpha 1
CREBBP CREB binding protein
CROCC ciliary rootlet coiled-coil, rootletin
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DLK2 delta-like 2 homolog (Drosophila)
DOK4 docking protein 4
EDA ectodysplasin A
EHD1 EH-domain containing 1
FAM124B family with sequence similarity 124B
FGB fibrinogen beta chain
FGF16 fibroblast growth factor 16
FLOT1 flotillin 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GEM GTP binding protein overexpressed in skeletal muscle
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GIMAP6 GTPase, IMAP family member 6
GPR162 G protein-coupled receptor 162
GRM8 glutamate receptor, metabotropic 8
GSTTP1 glutathione S-transferase theta pseudogene 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JADE2 jade family PHD finger 2
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KLF12 Kruppel-like factor 12
KLF13 Kruppel-like factor 13
KRT75 keratin 75, type II
KRT83 keratin 83, type II
LOC284244 uncharacterized LOC284244
LRRN2 leucine rich repeat neuronal 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA4 melanoma antigen family A4
MAU2 MAU2 sister chromatid cohesion factor
MR1 major histocompatibility complex, class I-related
MTSS1L metastasis suppressor 1-like
PCBP3 poly(rC) binding protein 3
PCDHGA11 protocadherin gamma subfamily A, 11
PDE10A phosphodiesterase 10A
PDGFB platelet-derived growth factor beta polypeptide
PEG10 paternally expressed 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIPOX pipecolic acid oxidase
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PRB1 proline-rich protein BstNI subfamily 1
PRDM9 PR domain containing 9
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RCAN1 regulator of calcineurin 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNDC3A RUN domain containing 3A
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC43A3 solute carrier family 43, member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SNAP25 synaptosomal-associated protein, 25kDa
SOCS1 suppressor of cytokine signaling 1
SPEG SPEG complex locus
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
STK24 serine/threonine kinase 24
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TIMP3 TIMP metallopeptidase inhibitor 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIM2 tripartite motif containing 2
TTLL7 tubulin tyrosine ligase-like family member 7
VILL villin-like
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
ZNF137P zinc finger protein 137, pseudogene
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ACTL8 actin-like 8
ALS2CL ALS2 C-terminal like
ANXA2P3 annexin A2 pseudogene 3
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ASIC1 acid sensing (proton gated) ion channel 1
AUH AU RNA binding protein/enoyl-CoA hydratase
AUTS2 autism susceptibility candidate 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BPHL biphenyl hydrolase-like (serine hydrolase)
C17ORF80 chromosome 17 open reading frame 80
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC132 coiled-coil domain containing 132
CCDC91 coiled-coil domain containing 91
CD82 CD82 molecule
CD8A CD8a molecule
CHML choroideremia-like (Rab escort protein 2)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CNR2 cannabinoid receptor 2 (macrophage)
CNTFR ciliary neurotrophic factor receptor
CPB1 carboxypeptidase B1 (tissue)
CRELD1 cysteine-rich with EGF-like domains 1
DBF4B DBF4 zinc finger B
DES desmin
DGAT1 diacylglycerol O-acyltransferase 1
DNM3 dynamin 3
EFNA3 ephrin-A3
ELSPBP1 epididymal sperm binding protein 1
EN2 engrailed homeobox 2
EPHX2 epoxide hydrolase 2, cytoplasmic
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EVA1B eva-1 homolog B (C. elegans)
FAM76A family with sequence similarity 76, member A
FMOD fibromodulin
GATA4 GATA binding protein 4
GPR21 G protein-coupled receptor 21
HIST1H1E histone cluster 1, H1e
HIST1H2BJ histone cluster 1, H2bj
HOXA4 homeobox A4
IFI35 interferon-induced protein 35
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
ITGA10 integrin, alpha 10
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KREMEN2 kringle containing transmembrane protein 2
LINC00597 long intergenic non-protein coding RNA 597
LMX1B LIM homeobox transcription factor 1, beta
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC20 leucine rich repeat containing 20
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MRPL52 mitochondrial ribosomal protein L52
MTA2 metastasis associated 1 family, member 2
N4BP3 NEDD4 binding protein 3
NOL10 nucleolar protein 10
NOL12 nucleolar protein 12
NRSN2 neurensin 2
OGFRL1 opioid growth factor receptor-like 1
OVGP1 oviductal glycoprotein 1, 120kDa
OVOL1 ovo-like zinc finger 1
PACS1 phosphofurin acidic cluster sorting protein 1
PAOX polyamine oxidase (exo-N4-amino)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PQLC2 PQ loop repeat containing 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF208 ring finger protein 208
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SIPA1 signal-induced proliferation-associated 1
SLC22A14 solute carrier family 22, member 14
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPAG4 sperm associated antigen 4
SPIDR scaffolding protein involved in DNA repair
SPTBN2 spectrin, beta, non-erythrocytic 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STIM1 stromal interaction molecule 1
STK16 serine/threonine kinase 16
TEX40 testis expressed 40
TFF2 trefoil factor 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPYL2 TSPY-like 2
VIPR1 vasoactive intestinal peptide receptor 1
XK X-linked Kx blood group
ZBTB48 zinc finger and BTB domain containing 48
ZFHX4 zinc finger homeobox 4
ZNF41 zinc finger protein 41
ZNF480 zinc finger protein 480
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2