| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the betahistine-2472 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABLIM1 | actin binding LIM protein 1 |
| ACVR1B | activin A receptor, type IB |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| AIM1L | absent in melanoma 1-like |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ANGPTL2 | angiopoietin-like 2 |
| APOE | apolipoprotein E |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ATF7 | activating transcription factor 7 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CDC42 | cell division cycle 42 |
| CHI3L2 | chitinase 3-like 2 |
| CLEC4E | C-type lectin domain family 4, member E |
| CLMN | calmin (calponin-like, transmembrane) |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CPLX2 | complexin 2 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CUL2 | cullin 2 |
| CUL7 | cullin 7 |
| DACH1 | dachshund family transcription factor 1 |
| DCLK2 | doublecortin-like kinase 2 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DUSP4 | dual specificity phosphatase 4 |
| EFNA4 | ephrin-A4 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| FAM162A | family with sequence similarity 162, member A |
| FBXO4 | F-box protein 4 |
| FLOT1 | flotillin 1 |
| FRZB | frizzled-related protein |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GAN | gigaxonin |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPR35 | G protein-coupled receptor 35 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HOXC11 | homeobox C11 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL6ST | interleukin 6 signal transducer |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| JAK3 | Janus kinase 3 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| LOC647070 | uncharacterized LOC647070 |
| MAP7 | microtubule-associated protein 7 |
| MAX | MYC associated factor X |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MYT1 | myelin transcription factor 1 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDLIM4 | PDZ and LIM domain 4 |
| PDLIM5 | PDZ and LIM domain 5 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLK3 | polo-like kinase 3 |
| PLSCR3 | phospholipid scramblase 3 |
| RAB11B | RAB11B, member RAS oncogene family |
| RB1 | retinoblastoma 1 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SMAD5 | SMAD family member 5 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SNW1 | SNW domain containing 1 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPPL2B | signal peptide peptidase like 2B |
| SSTR5 | somatostatin receptor 5 |
| STS | steroid sulfatase (microsomal), isozyme S |
| TAS2R1 | taste receptor, type 2, member 1 |
| THBS1 | thrombospondin 1 |
| THBS2 | thrombospondin 2 |
| TMEM180 | transmembrane protein 180 |
| TMEM2 | transmembrane protein 2 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TTC38 | tetratricopeptide repeat domain 38 |
| ULBP2 | UL16 binding protein 2 |
| ZFP64 | ZFP64 zinc finger protein |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF702P | zinc finger protein 702, pseudogene |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACO1 | aconitase 1, soluble |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| ADGRL3 | adhesion G protein-coupled receptor L3 |
| AGO4 | argonaute RISC catalytic component 4 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALS2CL | ALS2 C-terminal like |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CBX4 | chromobox homolog 4 |
| CDC37L1 | cell division cycle 37-like 1 |
| CENPT | centromere protein T |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CPTP | ceramide-1-phosphate transfer protein |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DOK3 | docking protein 3 |
| DPEP2 | dipeptidase 2 |
| DSPP | dentin sialophosphoprotein |
| DUSP8 | dual specificity phosphatase 8 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EML4 | echinoderm microtubule associated protein like 4 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM188A | family with sequence similarity 188, member A |
| FBRS | fibrosin |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO31 | F-box protein 31 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FLT4 | fms-related tyrosine kinase 4 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GALK1 | galactokinase 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GRIP2 | glutamate receptor interacting protein 2 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HPSE | heparanase |
| HRH2 | histamine receptor H2 |
| IL3RA | interleukin 3 receptor, alpha (low affinity) |
| INO80D | INO80 complex subunit D |
| IQCG | IQ motif containing G |
| IRS1 | insulin receptor substrate 1 |
| KIAA1107 | KIAA1107 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRRK1 | leucine-rich repeat kinase 1 |
| LTC4S | leukotriene C4 synthase |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAGEF1 | melanoma antigen family F1 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MRAS | muscle RAS oncogene homolog |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PDE6H | phosphodiesterase 6H, cGMP-specific, cone, gamma |
| PGM3 | phosphoglucomutase 3 |
| PIPOX | pipecolic acid oxidase |
| PIR | pirin (iron-binding nuclear protein) |
| PITX2 | paired-like homeodomain 2 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCD1 | phospholipase C, delta 1 |
| POLL | polymerase (DNA directed), lambda |
| POMT1 | protein-O-mannosyltransferase 1 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB17 | RAB17, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| REC8 | REC8 meiotic recombination protein |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SIL1 | SIL1 nucleotide exchange factor |
| SIRT6 | sirtuin 6 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| TBC1D19 | TBC1 domain family, member 19 |
| TBCCD1 | TBCC domain containing 1 |
| THEM6 | thioesterase superfamily member 6 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM209 | transmembrane protein 209 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| UPK3A | uroplakin 3A |
| XAB2 | XPA binding protein 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF345 | zinc finger protein 345 |
| ZNF76 | zinc finger protein 76 |
