| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the betahistine-2833 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK2 | aarF domain containing kinase 2 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATP10B | ATPase, class V, type 10B |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BAIAP2 | BAI1-associated protein 2 |
| BAIAP3 | BAI1-associated protein 3 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CDC25C | cell division cycle 25C |
| CFAP45 | cilia and flagella associated protein 45 |
| COL6A1 | collagen, type VI, alpha 1 |
| CRMP1 | collapsin response mediator protein 1 |
| CUL3 | cullin 3 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DIO2 | deiodinase, iodothyronine, type II |
| EPHB2 | EPH receptor B2 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLOT1 | flotillin 1 |
| FN1 | fibronectin 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| IFNA4 | interferon, alpha 4 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL11 | interleukin 11 |
| IL1B | interleukin 1, beta |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IQCA1 | IQ motif containing with AAA domain 1 |
| ITGB5 | integrin, beta 5 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNE1 | potassium channel, voltage gated subfamily E regulatory beta subunit 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KEL | Kell blood group, metallo-endopeptidase |
| LAMB3 | laminin, beta 3 |
| LIF | leukemia inhibitory factor |
| LRRC48 | leucine rich repeat containing 48 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MLXIP | MLX interacting protein |
| MXD4 | MAX dimerization protein 4 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NCOA2 | nuclear receptor coactivator 2 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PCDH1 | protocadherin 1 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PHF20 | PHD finger protein 20 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRF1 | perforin 1 (pore forming protein) |
| RAMP3 | receptor (G protein-coupled) activity modifying protein 3 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SOAT2 | sterol O-acyltransferase 2 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STAB1 | stabilin 1 |
| STAB2 | stabilin 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| TBX5 | T-box 5 |
| TDRKH | tudor and KH domain containing |
| TLE2 | transducin-like enhancer of split 2 |
| TLR2 | toll-like receptor 2 |
| TONSL | tonsoku-like, DNA repair protein |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TUBA3C | tubulin, alpha 3c |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZNF614 | zinc finger protein 614 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCL9 | B-cell CLL/lymphoma 9 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C11ORF80 | chromosome 11 open reading frame 80 |
| CAPN15 | calpain 15 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CUEDC1 | CUE domain containing 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNA2 | DNA replication helicase/nuclease 2 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| DSCAM | Down syndrome cell adhesion molecule |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| EPPK1 | epiplakin 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| F2R | coagulation factor II (thrombin) receptor |
| FBRS | fibrosin |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GK3P | glycerol kinase 3 pseudogene |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HOXC13 | homeobox C13 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HYI | hydroxypyruvate isomerase (putative) |
| ICK | intestinal cell (MAK-like) kinase |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IREB2 | iron-responsive element binding protein 2 |
| KIAA0319L | KIAA0319-like |
| KLHL25 | kelch-like family member 25 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LMNB1 | lamin B1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MED18 | mediator complex subunit 18 |
| MIS18BP1 | MIS18 binding protein 1 |
| MYO1E | myosin IE |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPY1R | neuropeptide Y receptor Y1 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PITX2 | paired-like homeodomain 2 |
| POLH | polymerase (DNA directed), eta |
| POLL | polymerase (DNA directed), lambda |
| PRPH | peripherin |
| RAB27B | RAB27B, member RAS oncogene family |
| RBBP5 | retinoblastoma binding protein 5 |
| RFX7 | regulatory factor X, 7 |
| RLN2 | relaxin 2 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SIRT2 | sirtuin 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SNX16 | sorting nexin 16 |
| SPIDR | scaffolding protein involved in DNA repair |
| SRPX | sushi-repeat containing protein, X-linked |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBX19 | T-box 19 |
| TMEM120B | transmembrane protein 120B |
| TMEM159 | transmembrane protein 159 |
| TOLLIP | toll interacting protein |
| TPCN1 | two pore segment channel 1 |
| TRAIP | TRAF interacting protein |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| VASH2 | vasohibin 2 |
| VGF | VGF nerve growth factor inducible |
| WDR25 | WD repeat domain 25 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF250 | zinc finger protein 250 |
| ZNF324 | zinc finger protein 324 |
| ZNF492 | zinc finger protein 492 |
| ZNF669 | zinc finger protein 669 |
| ZNF721 | zinc finger protein 721 |
| ZNF787 | zinc finger protein 787 |
| ZNF816 | zinc finger protein 816 |
