| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the betahistine-4956 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACO2 | aconitase 2, mitochondrial |
| AHI1 | Abelson helper integration site 1 |
| AIF1 | allograft inflammatory factor 1 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ASPN | asporin |
| BBC3 | BCL2 binding component 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CD6 | CD6 molecule |
| CD82 | CD82 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CLDN16 | claudin 16 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DFNA5 | deafness, autosomal dominant 5 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOCK1 | dedicator of cytokinesis 1 |
| EDNRB | endothelin receptor type B |
| EXOSC1 | exosome component 1 |
| FAM131A | family with sequence similarity 131, member A |
| FAM46C | family with sequence similarity 46, member C |
| FSCN1 | fascin actin-bundling protein 1 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GPR1 | G protein-coupled receptor 1 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HGD | homogentisate 1,2-dioxygenase |
| HOXB2 | homeobox B2 |
| HOXB5 | homeobox B5 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IDS | iduronate 2-sulfatase |
| IL21 | interleukin 21 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ISL1 | ISL LIM homeobox 1 |
| JPH3 | junctophilin 3 |
| JRK | Jrk homolog (mouse) |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KRT19P2 | keratin 19 pseudogene 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MX1 | MX dynamin-like GTPase 1 |
| NKTR | natural killer cell triggering receptor |
| NOP16 | NOP16 nucleolar protein |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OLFML2A | olfactomedin-like 2A |
| OVOL1 | ovo-like zinc finger 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPAG4 | sperm associated antigen 4 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STX7 | syntaxin 7 |
| TBX3 | T-box 3 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TECTA | tectorin alpha |
| THBD | thrombomodulin |
| TLR5 | toll-like receptor 5 |
| TMEM144 | transmembrane protein 144 |
| TRIM29 | tripartite motif containing 29 |
| TTC9 | tetratricopeptide repeat domain 9 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| VN1R1 | vomeronasal 1 receptor 1 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WSCD1 | WSC domain containing 1 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF223 | zinc finger protein 223 |
| ZNF44 | zinc finger protein 44 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ABHD17A | abhydrolase domain containing 17A |
| ADCY6 | adenylate cyclase 6 |
| AKIP1 | A kinase (PRKA) interacting protein 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CASD1 | CAS1 domain containing 1 |
| CBR1 | carbonyl reductase 1 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CFD | complement factor D (adipsin) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLDN15 | claudin 15 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CNPY3 | canopy FGF signaling regulator 3 |
| CORO1A | coronin, actin binding protein, 1A |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXORF40A | chromosome X open reading frame 40A |
| CYB5R1 | cytochrome b5 reductase 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| DVL1 | dishevelled segment polarity protein 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNA3 | ephrin-A3 |
| EIF6 | eukaryotic translation initiation factor 6 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM127B | family with sequence similarity 127, member B |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GOLGA8B | golgin A8 family, member B |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HAUS4 | HAUS augmin-like complex, subunit 4 |
| HOXC13 | homeobox C13 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| ICT1 | immature colon carcinoma transcript 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IL17RA | interleukin 17 receptor A |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KLHL28 | kelch-like family member 28 |
| LMNB1 | lamin B1 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MEIS1 | Meis homeobox 1 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MON1B | MON1 secretory trafficking family member B |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NABP2 | nucleic acid binding protein 2 |
| NBAS | neuroblastoma amplified sequence |
| NEK11 | NIMA-related kinase 11 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPY1R | neuropeptide Y receptor Y1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PC | pyruvate carboxylase |
| PCYOX1L | prenylcysteine oxidase 1 like |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCD1 | phospholipase C, delta 1 |
| PLD3 | phospholipase D family, member 3 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| POMZP3 | POM121 and ZP3 fusion |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RGS17 | regulator of G-protein signaling 17 |
| RNF123 | ring finger protein 123 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCPEP1 | serine carboxypeptidase 1 |
| SERTAD3 | SERTA domain containing 3 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STX1A | syntaxin 1A (brain) |
| SYNGR3 | synaptogyrin 3 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TEX264 | testis expressed 264 |
| TMEM109 | transmembrane protein 109 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM25 | tripartite motif containing 25 |
| TSPAN1 | tetraspanin 1 |
| VAX2 | ventral anterior homeobox 2 |
| XYLT2 | xylosyltransferase II |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF212 | zinc finger protein 212 |
| ZNF365 | zinc finger protein 365 |
| ZNF510 | zinc finger protein 510 |
| ZNF668 | zinc finger protein 668 |
