| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the betahistine-6611 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BMP8B | bone morphogenetic protein 8b |
| BTG2 | BTG family, member 2 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CD300A | CD300a molecule |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| DENND2A | DENN/MADD domain containing 2A |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DLG3 | discs, large homolog 3 (Drosophila) |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOCK6 | dedicator of cytokinesis 6 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EGR1 | early growth response 1 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FLT1 | fms-related tyrosine kinase 1 |
| FOLR2 | folate receptor 2 (fetal) |
| FUS | FUS RNA binding protein |
| GLB1L | galactosidase, beta 1-like |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR182 | G protein-coupled receptor 182 |
| GRM6 | glutamate receptor, metabotropic 6 |
| HEMK1 | HemK methyltransferase family member 1 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HOXC10 | homeobox C10 |
| HOXC5 | homeobox C5 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGFBP1 | insulin-like growth factor binding protein 1 |
| IL13 | interleukin 13 |
| KALRN | kalirin, RhoGEF kinase |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCTD14 | potassium channel tetramerization domain containing 14 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KIFC3 | kinesin family member C3 |
| KLK7 | kallikrein-related peptidase 7 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT7 | keratin 7, type II |
| LOC57399 | uncharacterized gastric protein ZA52P |
| LOX | lysyl oxidase |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MTMR7 | myotubularin related protein 7 |
| NOL10 | nucleolar protein 10 |
| NPAS3 | neuronal PAS domain protein 3 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PAPPA2 | pappalysin 2 |
| PAX2 | paired box 2 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PLK4 | polo-like kinase 4 |
| PODXL2 | podocalyxin-like 2 |
| POU6F1 | POU class 6 homeobox 1 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PVR | poliovirus receptor |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RUNDC3B | RUN domain containing 3B |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SAMD4A | sterile alpha motif domain containing 4A |
| SELL | selectin L |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SETD1A | SET domain containing 1A |
| SIRT4 | sirtuin 4 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPATA6 | spermatogenesis associated 6 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SSTR4 | somatostatin receptor 4 |
| TEX13A | testis expressed 13A |
| TLK1 | tousled-like kinase 1 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TSC22D2 | TSC22 domain family, member 2 |
| UPK2 | uroplakin 2 |
| WDR25 | WD repeat domain 25 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF215 | zinc finger protein 215 |
| ZNF235 | zinc finger protein 235 |
| ZNF254 | zinc finger protein 254 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| AGO4 | argonaute RISC catalytic component 4 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CAPN15 | calpain 15 |
| CAPN5 | calpain 5 |
| CARD8 | caspase recruitment domain family, member 8 |
| CBX4 | chromobox homolog 4 |
| CCDC94 | coiled-coil domain containing 94 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDH7 | cadherin 7, type 2 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CST1 | cystatin SN |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYBRD1 | cytochrome b reductase 1 |
| DBF4B | DBF4 zinc finger B |
| DEAF1 | DEAF1 transcription factor |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DSPP | dentin sialophosphoprotein |
| DUSP8 | dual specificity phosphatase 8 |
| ERCC4 | excision repair cross-complementation group 4 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FLT4 | fms-related tyrosine kinase 4 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HAMP | hepcidin antimicrobial peptide |
| HDAC7 | histone deacetylase 7 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFT54 | intraflagellar transport 54 |
| IL7R | interleukin 7 receptor |
| KIAA1456 | KIAA1456 |
| KIF13B | kinesin family member 13B |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LAMC3 | laminin, gamma 3 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LYRM9 | LYR motif containing 9 |
| MAGEF1 | melanoma antigen family F1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MGP | matrix Gla protein |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| NBEAL2 | neurobeachin-like 2 |
| NDP | Norrie disease (pseudoglioma) |
| NKX3-2 | NK3 homeobox 2 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLXNB3 | plexin B3 |
| POLL | polymerase (DNA directed), lambda |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB3B | RAB3B, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAI2 | retinoic acid induced 2 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SIX3 | SIX homeobox 3 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPAG7 | sperm associated antigen 7 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STX1A | syntaxin 1A (brain) |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SYNPO | synaptopodin |
| TBC1D17 | TBC1 domain family, member 17 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRAIP | TRAF interacting protein |
| TRIM66 | tripartite motif containing 66 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VARS | valyl-tRNA synthetase |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF385D | zinc finger protein 385D |
| ZNF428 | zinc finger protein 428 |
| ZNF510 | zinc finger protein 510 |
| ZNF574 | zinc finger protein 574 |
