betamethasone-1590 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the betamethasone-1590 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ADD2 adducin 2 (beta)
ADORA3 adenosine A3 receptor
AHNAK AHNAK nucleoprotein
AIF1 allograft inflammatory factor 1
AKAP7 A kinase (PRKA) anchor protein 7
AMT aminomethyltransferase
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AREG amphiregulin
ARG1 arginase 1
ATXN7 ataxin 7
AZI2 5-azacytidine induced 2
BCAP29 B-cell receptor-associated protein 29
CA12 carbonic anhydrase XII
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL20 chemokine (C-C motif) ligand 20
CCPG1 cell cycle progression 1
CIZ1 CDKN1A interacting zinc finger protein 1
CPD carboxypeptidase D
CRCP CGRP receptor component
CXCR4 chemokine (C-X-C motif) receptor 4
DSN1 DSN1, MIS12 kinetochore complex component
DUSP1 dual specificity phosphatase 1
EIF1 eukaryotic translation initiation factor 1
ELMO2 engulfment and cell motility 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM134A family with sequence similarity 134, member A
FEM1B fem-1 homolog b (C. elegans)
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT3 fms-related tyrosine kinase 3
FN1 fibronectin 1
FPR1 formyl peptide receptor 1
GHRHR growth hormone releasing hormone receptor
GPR65 G protein-coupled receptor 65
HIST1H2BE histone cluster 1, H2be
HLA-DOA major histocompatibility complex, class II, DO alpha
IFNGR1 interferon gamma receptor 1
IGFBP7 insulin-like growth factor binding protein 7
IL1R2 interleukin 1 receptor, type II
IRAK3 interleukin-1 receptor-associated kinase 3
ITGA7 integrin, alpha 7
KANK1 KN motif and ankyrin repeat domains 1
KAT2B K(lysine) acetyltransferase 2B
KLF13 Kruppel-like factor 13
KLF9 Kruppel-like factor 9
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LPIN2 lipin 2
MACF1 microtubule-actin crosslinking factor 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAML3 mastermind-like 3 (Drosophila)
MAP2K1 mitogen-activated protein kinase kinase 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCAM melanoma cell adhesion molecule
METTL7A methyltransferase like 7A
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MT1HL1 metallothionein 1H-like 1
MVK mevalonate kinase
MYL10 myosin, light chain 10, regulatory
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NCF1C neutrophil cytosolic factor 1C pseudogene
NET1 neuroepithelial cell transforming 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFX1 nuclear transcription factor, X-box binding 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OGFR opioid growth factor receptor
PER1 period circadian clock 1
PLCD1 phospholipase C, delta 1
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTMA prothymosin, alpha
RAB17 RAB17, member RAS oncogene family
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RECQL4 RecQ protein-like 4
RHEB Ras homolog enriched in brain
RHOH ras homolog family member H
RIOK3 RIO kinase 3
RNF144A ring finger protein 144A
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL7 ribosomal protein L7
RPS2 ribosomal protein S2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SAP30 Sin3A-associated protein, 30kDa
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC2 syndecan 2
SLA Src-like-adaptor
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SOAT1 sterol O-acyltransferase 1
TPST1 tyrosylprotein sulfotransferase 1
TSC22D3 TSC22 domain family, member 3
TUBA4B tubulin, alpha 4b
UBQLN4 ubiquilin 4
USF2 upstream transcription factor 2, c-fos interacting
VIPR2 vasoactive intestinal peptide receptor 2
ZBTB16 zinc finger and BTB domain containing 16
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF280D zinc finger protein 280D
ZNF3 zinc finger protein 3

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AGO1 argonaute RISC catalytic component 1
ANAPC2 anaphase promoting complex subunit 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARMC7 armadillo repeat containing 7
ARMCX5 armadillo repeat containing, X-linked 5
ASRGL1 asparaginase like 1
BABAM1 BRISC and BRCA1 A complex member 1
BATF basic leucine zipper transcription factor, ATF-like
BCL7C B-cell CLL/lymphoma 7C
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1ORF54 chromosome 1 open reading frame 54
C8ORF44 chromosome 8 open reading frame 44
CCL2 chemokine (C-C motif) ligand 2
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP170B centrosomal protein 170B
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COMMD9 COMM domain containing 9
EAF2 ELL associated factor 2
EGR2 early growth response 2
ERCC2 excision repair cross-complementation group 2
ERCC8 excision repair cross-complementation group 8
ERF Ets2 repressor factor
ERO1L ERO1-like (S. cerevisiae)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCHO1 FCH domain only 1
FURIN furin (paired basic amino acid cleaving enzyme)
GID8 GID complex subunit 8
GMPPB GDP-mannose pyrophosphorylase B
GPATCH3 G patch domain containing 3
GPR18 G protein-coupled receptor 18
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IER3 immediate early response 3
IFITM3 interferon induced transmembrane protein 3
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JRKL JRK-like
KIFC1 kinesin family member C1
LAMP5 lysosomal-associated membrane protein family, member 5
LGALS9 lectin, galactoside-binding, soluble, 9
LIAS lipoic acid synthetase
LPXN leupaxin
LZTFL1 leucine zipper transcription factor-like 1
MACROD1 MACRO domain containing 1
MAGEF1 melanoma antigen family F1
MATK megakaryocyte-associated tyrosine kinase
MCM3AP-AS1 MCM3AP antisense RNA 1
MFSD11 major facilitator superfamily domain containing 11
MITF microphthalmia-associated transcription factor
MMP2 matrix metallopeptidase 2
MPDU1 mannose-P-dolichol utilization defect 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO9A myosin IXA
NABP2 nucleic acid binding protein 2
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NRIP3 nuclear receptor interacting protein 3
NUP93 nucleoporin 93kDa
OR2C1 olfactory receptor, family 2, subfamily C, member 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARP16 poly (ADP-ribose) polymerase family, member 16
PELI1 pellino E3 ubiquitin protein ligase 1
PELP1 proline, glutamate and leucine rich protein 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PNOC prepronociceptin
PNRC1 proline-rich nuclear receptor coactivator 1
POLE polymerase (DNA directed), epsilon, catalytic subunit
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PTOV1 prostate tumor overexpressed 1
RAB4B RAB4B, member RAS oncogene family
RBM47 RNA binding motif protein 47
RGS2 regulator of G-protein signaling 2
RNF220 ring finger protein 220
RPL39L ribosomal protein L39-like
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPUSD2 RNA pseudouridylate synthase domain containing 2
RWDD2B RWD domain containing 2B
SASH3 SAM and SH3 domain containing 3
SCYL2 SCY1-like 2 (S. cerevisiae)
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SNRPC small nuclear ribonucleoprotein polypeptide C
SRRD SRR1 domain containing
STAC SH3 and cysteine rich domain
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAC3 tachykinin 3
TBL3 transducin (beta)-like 3
TEX30 testis expressed 30
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
USB1 U6 snRNA biogenesis 1
ZNF189 zinc finger protein 189
ZNF529 zinc finger protein 529
ZNF654 zinc finger protein 654
ZSCAN5A zinc finger and SCAN domain containing 5A