betamethasone-5328 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the betamethasone-5328 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ADRBK1 adrenergic, beta, receptor kinase 1
AMPD3 adenosine monophosphate deaminase 3
ARMC4 armadillo repeat containing 4
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
ATP9A ATPase, class II, type 9A
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BMP4 bone morphogenetic protein 4
C17ORF59 chromosome 17 open reading frame 59
CACFD1 calcium channel flower domain containing 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC9 coiled-coil domain containing 9
CDC25C cell division cycle 25C
CDK17 cyclin-dependent kinase 17
CDK3 cyclin-dependent kinase 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP164 centrosomal protein 164kDa
CLCN7 chloride channel, voltage-sensitive 7
CTNS cystinosin, lysosomal cystine transporter
CXXC1 CXXC finger protein 1
CYHR1 cysteine/histidine-rich 1
DAGLA diacylglycerol lipase, alpha
DOK4 docking protein 4
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EPOR erythropoietin receptor
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM76A family with sequence similarity 76, member A
GLI3 GLI family zinc finger 3
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR137 G protein-coupled receptor 137
HEG1 heart development protein with EGF-like domains 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
JRK Jrk homolog (mouse)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
LIN7A lin-7 homolog A (C. elegans)
LMNA lamin A/C
LPIN1 lipin 1
LRRC61 leucine rich repeat containing 61
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAX MYC associated factor X
MBD3 methyl-CpG binding domain protein 3
MET MET proto-oncogene, receptor tyrosine kinase
MST1 macrophage stimulating 1
MYO1F myosin IF
NCR2 natural cytotoxicity triggering receptor 2
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOP16 NOP16 nucleolar protein
NPTX2 neuronal pentraxin II
NPY2R neuropeptide Y receptor Y2
NR2F6 nuclear receptor subfamily 2, group F, member 6
OSMR oncostatin M receptor
PDLIM7 PDZ and LIM domain 7 (enigma)
PEX14 peroxisomal biogenesis factor 14
PLK3 polo-like kinase 3
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRAMEF11 PRAME family member 11
PRDX2 peroxiredoxin 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RNF122 ring finger protein 122
S100A4 S100 calcium binding protein A4
SCARB2 scavenger receptor class B, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SETD8 SET domain containing (lysine methyltransferase) 8
SFTPB surfactant protein B
SFXN3 sideroflexin 3
SH2D3A SH2 domain containing 3A
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLMO1 slowmo homolog 1 (Drosophila)
SOCS1 suppressor of cytokine signaling 1
SPAG4 sperm associated antigen 4
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SREBF2 sterol regulatory element binding transcription factor 2
SRSF1 serine/arginine-rich splicing factor 1
SS18 synovial sarcoma translocation, chromosome 18
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TMOD1 tropomodulin 1
TP53I11 tumor protein p53 inducible protein 11
TRIM25 tripartite motif containing 25
TTLL5 tubulin tyrosine ligase-like family member 5
VDAC3 voltage-dependent anion channel 3
WFDC2 WAP four-disulfide core domain 2
ZBTB17 zinc finger and BTB domain containing 17
ZHX3 zinc fingers and homeoboxes 3
ZNF133 zinc finger protein 133
ZNF350 zinc finger protein 350
ZNF609 zinc finger protein 609
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADRA2C adrenoceptor alpha 2C
AEN apoptosis enhancing nuclease
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANXA2P3 annexin A2 pseudogene 3
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ATAD3A ATPase family, AAA domain containing 3A
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BPHL biphenyl hydrolase-like (serine hydrolase)
C5 complement component 5
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CBR4 carbonyl reductase 4
CCDC109B coiled-coil domain containing 109B
CD3EAP CD3e molecule, epsilon associated protein
CHML choroideremia-like (Rab escort protein 2)
CLDN15 claudin 15
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRLF3 cytokine receptor-like factor 3
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DAP death-associated protein
DBR1 debranching RNA lariats 1
DCAF17 DDB1 and CUL4 associated factor 17
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNA2 DNA replication helicase/nuclease 2
DNM1 dynamin 1
DTWD1 DTW domain containing 1
E2F6 E2F transcription factor 6
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ETAA1 Ewing tumor-associated antigen 1
EVPL envoplakin
FAM155B family with sequence similarity 155, member B
FBXL15 F-box and leucine-rich repeat protein 15
FBXO5 F-box protein 5
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLCE glucuronic acid epimerase
GRWD1 glutamate-rich WD repeat containing 1
GTPBP2 GTP binding protein 2
GUSBP3 glucuronidase, beta pseudogene 3
GYS1 glycogen synthase 1 (muscle)
HILPDA hypoxia inducible lipid droplet-associated
IFI6 interferon, alpha-inducible protein 6
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
ITGAV integrin, alpha V
JADE3 jade family PHD finger 3
KLHL12 kelch-like family member 12
KLHL36 kelch-like family member 36
KRBOX4 KRAB box domain containing 4
LINC00339 long intergenic non-protein coding RNA 339
LOC100272216 uncharacterized LOC100272216
LOC100287590 uncharacterized LOC100287590
LZTFL1 leucine zipper transcription factor-like 1
MELK maternal embryonic leucine zipper kinase
MGST3 microsomal glutathione S-transferase 3
MIPEP mitochondrial intermediate peptidase
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MTERF1 mitochondrial transcription termination factor 1
NHEJ1 nonhomologous end-joining factor 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAQR6 progestin and adipoQ receptor family member VI
PILRB paired immunoglobin-like type 2 receptor beta
PTBP2 polypyrimidine tract binding protein 2
PTPRU protein tyrosine phosphatase, receptor type, U
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PYGB phosphorylase, glycogen; brain
RIBC2 RIB43A domain with coiled-coils 2
RNF130 ring finger protein 130
RNFT2 ring finger protein, transmembrane 2
RPL39L ribosomal protein L39-like
RUFY2 RUN and FYVE domain containing 2
SALL2 spalt-like transcription factor 2
SAV1 salvador family WW domain containing protein 1
SCAMP4 secretory carrier membrane protein 4
SCUBE2 signal peptide, CUB domain, EGF-like 2
SFT2D2 SFT2 domain containing 2
SH3BGR SH3 domain binding glutamate-rich protein
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC46A3 solute carrier family 46, member 3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SNX6 sorting nexin 6
SSNA1 Sjogren syndrome nuclear autoantigen 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBCC tubulin folding cofactor C
TMEM168 transmembrane protein 168
TMEM2 transmembrane protein 2
TRAPPC2 trafficking protein particle complex 2
TTF2 transcription termination factor, RNA polymerase II
UBP1 upstream binding protein 1 (LBP-1a)
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFP69B ZFP69 zinc finger protein B
ZNF140 zinc finger protein 140
ZNF668 zinc finger protein 668
ZNF721 zinc finger protein 721
ZW10 zw10 kinetochore protein